Pediatrics

Host: Adam Ehrlich, MD, MPH

Guest: Philip Stein, MD

The majority of adolescents with inflammatory bowel disease (IBD) will transition from a pediatric to an adult specialist. This process can be daunting, especially if patients are not ready to take control of their health care. However, with the right communication and preparation, the transition can be smooth for the patient, parent, and physician. Host Dr. Adam Ehrlich joins Dr. Philip Stein, a pediatric gastroenterologist at St. Christopher’s Hospital for Children, to discuss how physicians can best prepare patients to transition and overcome potential difficulties.

Host: Brian P. McDonough, MD, FAAFP

Guest: Howard Spiva

Wearing a helmet is an overlooked but critical safety precaution, particularly among children. Attorney Howard Spiva knows the lifelong struggle of individuals recovering from traumatic brain injuries, having devoting much of his career to providing helmet safety education for children. Joined by host Brian McDonough, Mr. Spiva discusses important details about helmet safety, the current status of helmet laws, and continuing efforts to reduce traumatic brain injuries nationwide.

Host: Maurice Pickard, MD

Guest: Elijah Nealy, PhD

These days, it is practically impossible not to hear about some aspect of transgender life, and kids are coming out as trans at younger and younger ages. But what resources are available to parents, teachers, and mental health professionals who need to support these children?

Host Dr. Maurice Pickard chats with Elijah C. Nealy, therapist and former deputy executive director of New York City’s LGBT Community Center. Mr. Nealy is the author of Transgender Children and Youth: Cultivating Pride and Joy with Families in Transition, which provides insights about the physical, social, and emotional aspects of transition and the best practices to support trans kids.

Vedolizumab as Induction and Maintenance Therapy for Crohn's Disease in Patients Naïve to or Who Have Failed Tumor Necrosis Factor Antagonist Therapy.

Sands BE1, Sandborn WJ, Van Assche G, Lukas M, Xu J, James A, Abhyankar B, Lasch K.

BACKGROUND:

Vedolizumab is a gut-selective α4β7 integrin antagonist for the treatment of moderately to severely active Crohn's disease (CD). Aims of this study were to characterize the efficacy and safety of vedolizumab induction and maintenance therapy in patients who were naïve to tumor necrosis factor-alpha (TNF-α) antagonist therapy (TNF-naïve) or who had discontinued TNF-α antagonist therapy because of inadequate response (i.e., primary nonresponse), loss of response, or intolerance (collectively classified as the TNF-failure population).

METHODS:

Post hoc analyses of the efficacy data for 516 TNF-naïve and 960 TNF-failure patients from the GEMINI 2 and GEMINI 3 trials were evaluated at weeks 6, 10, and 52 and included clinical remission (CD Activity Index [CDAI] score ≤150), enhanced clinical response (≥100-point decrease from baseline in CDAI score), durable clinical remission (remission at ≥80% of visits), and corticosteroid-free remission. Adverse events were summarized for the TNF-naïve and TNF-failure subgroups by treatment received.

RESULTS:

Among patients who responded to vedolizumab induction at week 6, 48.9% …

The Food and Drug Administration (FDA) is restricting the use of codeine and tramadol medicines in children. Codeine is approved to treat pain and cough, and tramadol is approved to treat pain. These medicines carry serious risks, including slowed or difficult breathing and death, which appear to be a greater risk in children younger than 12 years, and should not be used in these children. These medicines should also be limited in some older children. Single-ingredient codeine and all tramadol-containing products are FDA-approved only for use in adults. The FDA is also recommending against the use of codeine and tramadol medicines in breastfeeding mothers due to possible harm to their infants.

As a result, the FDA is requiring several changes to the labels of all prescription medicines containing these drugs. These new actions further limit the use of these medicines beyond the 2013 restriction of codeine use in children younger than 18 years to treat pain after surgery to remove the tonsils and/or adenoids. The FDA is now adding:

• FDA’s strongest warning, called a Contraindication, to the drug labels of codeine and tramadol alerting that codeine should not be used to treat pain or cough and tramadol …

Guest: KT Park, MD

Recorded on location at the Crohn’s & Colitis Foundation's Annual Meeting in Orlando, host Dr. Sophie Balzora, Crohn's & Colitis Foundation Reach-IBD member and faculty advisor of the Greater New York Chapter Fellows' Education Committee, discusses general strategies for clinicians and families to optimize growth in pediatric IBD with Dr. K.T. Park, Assistant Professor of Pediatric Gastroenterology at Stanford University School of Medicine & Co-Director of Stanford Children’s Inflammatory Bowel Disease Center.

Host: Prathima Setty, MD

A couple of extra minutes attached to the umbilical cord at birth may translate into a significant boost in neurodevelopment several years later, research suggests.

Dr. Prathima Setty is joined by Dr. Kecia Gaither, a perinatal consultant at St. Lukes Hospital in Kansas City, MO as they talk about how delaying cutting the umbilical cord can be beneficial.

Host: Jennifer Caudle, DO

Sleep apnea in children can lead to many behavioral, school and social problems. Recent research has even suggested that children who snore loudly were found to be twice as likely to have learning problems as children who don’t snore. What can be done to minimize sleep apnea in children?

On this episode of Everyday Family Medicine, Dr. Jennifer Caudle speaks with Dr. Diana Batoon, dentist and founder of Bonita Dental in Scottsdale, Arizona. Dr. Batoon has devoted much of her dental practice and public education efforts around identifying and treating sleep apnea in children.

Host: David Weisman, MD

Dr. David Weisman explores a study from Wake Forest School of Medicine that examined the effects of concussions for youth football participants.

Host: Paul Rokuskie

As medical professionals gain better understandings of the etiologies, mechanisms, and progressions of autism spectrum disorder, they are looking for ways to standardize this diagnosis. This creates new needs to change the way autism is conceptualized clinically, from severity scales to behavioral impacts on quality of life.

Host Paul Rokuskie welcomes Dr. Sven Bolte, Professor of Child and Adolescent Psychiatric Science and Director of the Center of Neurodevelopmental Disorders at Karolinska Institute in Stockholm, Sweden. The two discuss the complex process for building new diagnostic criteria for autism spectrum disorder.