Petri Dish

Petri Dish

By Petri DishScienceLife Sciences
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Petri Dish episodes

  • Ep. 33.5 Bonus Minisode: CoronaTreatments

    For the 16 people out there that aren't sick of COVID-19/SARS-CoV-2 information already, here is another BONUS MINISODE on just that topic! This time around we're covering treatments that scientists and doctors around the world are trying to use to fight COVID-19. We discuss the WHO's new clinical trial to gather some data on these treatments, talk about 5 of the treatments more specifically, and then go into debunking mode!

    Useful links on the latest number of infected:

    https://covidtracking.com/us-daily/

    https://coronavirus.jhu.edu/map.html

    References:

    • https://www.sciencemag.org/news/2020/03/who-launches-global-megatrial-four-most-promising-coronavirus-treatments
    • https://www.nytimes.com/2020/03/23/health/coronavirus-drugs-remdesivir.html
    • https://www.reuters.com/article/us-health-coronavirus-gilead-sciences/gileads-potential-coronavirus-treatment-gets-fdas-orphan-drug-label-idUSKBN21A3PR
    • https://www.jbc.org/content/early/2020/02/24/jbc.AC120.013056.full.pdf
    • https://www.nature.com/articles/s41584-020-0372-x
    • https://www.sciencedirect.com/science/article/pii/S0166354220301145?via%3Dihub
    • http://www.mediterranee-infection.com/wp-content/uploads/2020/03/Hydroxychloroquine_final_DOI_IJAA.pdf
    • https://www.jstage.jst.go.jp/article/bst/14/1/14_2020.01047/_pdf/-char/en
    • http://www.zjujournals.com/med/CN/10.3785/j.issn.1008-9292.2020.03.03
    • https://www.ncbi.nlm.nih.gov/pubmed/12662125
    • https://www.nejm.org/doi/10.1056/NEJMoa2001282
    • https://www.fda.gov/vaccines-blood-biologics/investigational-new-drug-ind-or-device-exemption-ide-process-cber/investigational-covid-19-convalescent-plasma-emergency-inds
    • https://www.jci.org/articles/view/138003
    • https://www.latimes.com/science/story/2020-03-20/how-blood-from-people-who-survived-covid-19
    • https://www.thelancet.com/action/showPdf?pii=S2213-2600%2820%2930116-8
    • 34 min
    • Ep. 33 Pandemic: PLAGUE

      The second episode in our pandemic series is about one of the OGs, plague! This sucker has killed hundreds of millions of people in the past couple millennia, but has been brought low by antibiotics (yay SCIENCE!). But is it gone forever? Nah. Also, bubonic plague as a bioweapon?! It isn't a new idea...

      Promo this week is for Controller Disconnected Podcast! Check them out at  https://www.condisconnected.com/  and on twitter @condisconnected

      We are also on twitter @dishpodcast and on instagram @petridishpodcast AND have an email address [email protected]. Hit us up!

      References:

      • https://www.nationalgeographic.com/news/2014/1/140129-justinian-plague-black-death-bacteria-bubonic-pandemic/
      • https://www.cdc.gov/plague/maps/index.html
      • https://www.sciencedirect.com/science/article/abs/pii/S1286457999002051
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200711/
      • http://www.centerforhealthsecurity.org/our-work/publications/plague-fact-sheet
      • https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(14)60858-2/fulltext
      • https://www.usgs.gov/centers/nwhc/science/sylvatic-plague?qt-science_center_objects=0#qt-science_center_objects
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3256048/
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1200711/
      • https://emergency.cdc.gov/agent/agentlist-category.asp
      • http://www.bordeninstitute.army.mil/cwbw/default_index.htm
      • https://www.sciencedirect.com/science/article/pii/S2590053619300230
      • 1 hr
      • Ep. 32 Pandemic: Tuberculosis

        This new series of episodes we're doing is on different pandemic diseases throughout history, with our first disease being tuberculosis! The series won't be a bunch of episodes in a row, but as we do more and more diseases we will begin comparing different pandemics. This episode covers the modern tuberculosis situation (2 billion people infected!) and our long history with the disease. We'll talk about treatments, drug resistance, disease characteristics, and the vaccine.

        Featuring a promo for the great podcast Just the Zoo of Us, check them out! https://www.justthezooofus.com/ @JusttheZooofUs on twitter

        Become a patron at patreon.com/petridish!

        References:

        • https://www.who.int/tb/publications/factsheet_global.pdf
        • https://www.bcm.edu/departments/molecular-virology-and-microbiology/emerging-infections-and-biodefense/introduction-to-infectious-diseases
        • https://www.atsjournals.org/doi/full/10.1164/rccm.200402-140OE
        • https://www.cdc.gov/nchs/fastats/deaths.htm
        • https://www.nature.com/articles/nrmicro.2018.8
        • https://www.smithsonianmag.com/science-nature/how-tuberculosis-shaped-victorian-fashion-180959029/
        • https://www.cdc.gov/tb/publications/factsheets/general/mbovis.htm
        • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2946903/
        • https://www.aafp.org/afp/2005/1101/p1761.html
        • https://www.sciencedirect.com/science/article/pii/S0022534707022884
        • https://www.who.int/vaccine_safety/initiative/tools/BCG_Vaccine_rates_information_sheet.pdf
        • https://link.springer.com/chapter/10.1007/978-1-4939-6667-7_20
        • https://www.sciencedirect.com/science/article/pii/S0264410X14007099
        • https://www.ijidonline.com/article/S1201-9712(19)30100-6/pdf
        • https://www.nature.com/articles/nrurol.2014.15
        • https://www.canjurol.com/html/free-articles/V15I02-2-Legends_DrMorales.pdf
        • https://www.sciencedirect.com/science/article/pii/S1078143900000995?via%3Dihub
        • 49 min
        • Ep. 31 Dogs! Pupperinos Part 2
          This is the second half of our two-parter on mankind's best friend! Last week's episode covered domestication and breeds. This week is about dog behavior, dog jobs, and dog fritos feet.
          Featuring a promo for the podcast Snark Tank -- check them out on twitter @SnarkTankPod and at http://SnarkTankPod.com
          References:
          https://www.sciencedirect.com/science/article/pii/S0376635714000473
          https://www.tandfonline.com/doi/full/10.1080/14616734.2018.1517812
          https://www.nature.com/articles/s41598-017-12781-x
          https://www.pnas.org/content/116/29/14677?fbclid=IwAR3lu8dKSqFFvcuWQIK5KEzgiwQvH-ZfzvV4aIsCE_yIUSMqya5BiNFxxj0
          https://www.fasebj.org/doi/abs/10.1096/fasebj.31.1_supplement.577.3
          https://www.sciencedirect.com/science/article/pii/S2405844020301560?via%3Dihub
          https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2839826/
          https://www.thesprucepets.com/dog-paws-smell-like-corn-chips-3385624
          https://pdfs.semanticscholar.org/ae70/f4c8e88b76e6ac12de2c10b66ee8fb935cdc.pdf
          https://www.sciencedirect.com/science/article/abs/pii/S0039914018303552
          https://www.sciencedirect.com/science/article/abs/pii/S0376635717300104
          https://bmcurol.biomedcentral.com/articles/10.1186/1471-2490-14-22
          https://iopscience.iop.org/article/10.1088/1752-7163/ab716e/meta
          https://www.sciencedirect.com/science/article/abs/pii/S1558787817300539
          https://link.springer.com/article/10.1007/s10071-018-01234-1/tables/1?shared-article-renderer
          https://www.jneurosci.org/content/jneuro/39/39/7748.full.pdf
          https://royalsocietypublishing.org/doi/full/10.1098/rspb.2019.0716
          https://www.frontiersin.org/articles/10.3389/fpsyg.2017.01520/full#h5
          There are actually ~10 more references
          1 hr 4 min
        • Ep. 30.5 Bonus Minisode: Corona-USA
          SARS-CoV-2, HCOV-19, nCoV-19... Whatever you want to call this coronavirus, it is making a splash in countries all over the globe: big outbreaks in Italy, South Korea, and Iran, along with growing numbers of infected people (largely untested) in the USA. In this episode, Sean and Nathan discuss the US CDC's response to the coronavirus and dive a little into a paper about there being two potential 'strains' of this virus already.
          References:
          https://www.medrxiv.org/content/10.1101/2020.02.25.20027953v2
          https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30419-0/fulltext
          https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30462-1/fulltext
          https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30557-2/fulltext
          https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30551-1/fulltext
          https://www.nejm.org/doi/full/10.1056/NEJMoa2002032
          https://www.theatlantic.com/health/archive/2020/03/how-many-americans-have-been-tested-coronavirus/607597/
          22 min
        • Ep. 30 Dogs! (Because We Did One On Cats) Part 1

          Humankind's best friend! Pupperinos! In this week's episode of Petri Dish Nathan and Sean talk about dogs! This is part 1, where we talk about the domestication of dogs and some biological information about dog breeds! In part 2 we'll go into of the science of dog behavior and biology. 

          Featuring a promo for the podcast Controller Disconnected! Follow them @condisconnected on Twitter!

          Follow us too @dishpodcast and email us petridishpod -at- gmail.com. If you like what we do, consider giving us a buck a month at patreon.com/petridish

          References:

          • https://www.sciencedirect.com/science/article/pii/027841659190021O
          • https://royalsocietypublishing.org/doi/full/10.1098/rsos.160107
          • https://www.nature.com/articles/s41598-019-40468-y
          • https://www.frontiersin.org/articles/10.3389/fpsyg.2014.01582/full
          • https://www.tandfonline.com/doi/full/10.1080/08912963.2016.1262854
          • https://onlinelibrary.wiley.com/doi/full/10.1111/ede.12319
          • https://bmcbiol.biomedcentral.com/articles/10.1186/s12915-018-0535-2
          • https://www.sciencedirect.com/science/article/pii/S0169534719303027
          • https://www.biorxiv.org/content/10.1101/660829v2.full
          • https://royalsocietypublishing.org/doi/full/10.1098/rspb.2019.1929
          • https://www.mdpi.com/2073-4425/10/10/757/htm
          • https://www.sciencedirect.com/science/article/pii/S0305440316301789
          • https://academic.oup.com/mbe/article/30/5/1103/997804
          • https://science.sciencemag.org/content/352/6290/1228
          • https://www.mdpi.com/2073-4425/10/10/757/htm
          • https://link.springer.com/chapter/10.1007%2F13836_2018_27
          • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3384140/
          • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5705110/
          • https://academic.oup.com/dnaresearch/article/19/3/275/475438
          • 52 min
          • Ep. 29 Vaccines! Part 2

            Hi Folks! If you're just stopping by, consider listening to Vaccines Part 1 to get info on the types of vaccines and what ingredients go into making them -- we use some of those terms here! In this ep we talk about how vaccines work on a cell level, how long and how well different vaccines work, and wrap it up with next-generation vaccines!

            Featuring a promo for Dad and Daughter Movies Podcast -- follow them on twitter @DDMovies2!

            If you like what we do, consider tossing $1 a month our way at patreon.com/petridish. Follow us on twitter @dishpodcast! Email us at petridishpod -at- gmail.com

            References: 

            • https://www.npr.org/sections/goatsandsoda/2019/12/05/785177595/measles-numbers-were-bad-in-2018-this-year-theyre-even-worse
            • https://www.sciencemag.org/news/2019/04/how-long-do-vaccines-last-surprising-answers-may-help-protect-people-longer
            • https://www.who.int/biologicals/areas/vaccines/bcg/en/
            • https://www.nature.com/articles/s41586-019-1817-8
            • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274812/
            • https://stm.sciencemag.org/content/11/522/eaax7888.abstract
            • 44 min
            • Ep. 28.5 Bonus Minisode: Still Coronavirus!

              Hey! The novel coronavirus (now SARS-CoV-2, which causes COVID-19) is still out and about, doing naughty stuff! But what do we know about this sucker now, a couple of months in to this not-quite-pandemic-yet? What are the latest stats on the number of cases, what countries should we be looking at, what do we know now about the biology of COVID-19, and also conspiracy theories are dumb. Get some info on this latest outbreak here on Petri Dish!

              If you like what we're doing here at Petri Dish, consider chipping in $1 a month at our patreon: patreon.com/petridish

              Questions or concerns? Email us at petridishpod -at- gmail.com or tweet at us @dishpodcast!

              References:

              • https://www.biorxiv.org/content/10.1101/2020.01.30.927871v1
              • https://www.biorxiv.org/content/10.1101/2020.02.04.933135v1
              • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5457962/
              • https://www.nejm.org/doi/full/10.1056/NEJMoa2001191?query=recirc_mostViewed_railB_article
              • https://www.nejm.org/doi/full/10.1056/NEJMoa2001316?query=recirc_mostViewed_railB_article
              • https://www.biorxiv.org/content/10.1101/2020.01.23.916395v2
              • https://www.sciencemag.org/news/2020/02/paper-non-symptomatic-patient-transmitting-coronavirus-wrong
              • https://www.sciencedirect.com/science/article/pii/S0140673620302609
              • https://www.sciencedirect.com/science/article/abs/pii/S1567134820300447
              • https://www.sciencemag.org/news/2020/01/mining-coronavirus-genomes-clues-outbreak-s-origins
              • https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30251-8/fulltext
              • https://www.nature.com/articles/s41586-020-2012-7_reference.pdf
              • https://www.biorxiv.org/content/10.1101/2020.02.04.933135v1
              • https://www.biorxiv.org/content/10.1101/2020.02.19.950253v1
              • https://www.thelancet.com/pb-assets/Lancet/pdfs/S2213260020300795.pdf
              • https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)30411-6/fulltext
              • 19 min
              • Ep. 28 Vaccines! Part 1

                If you're a listener to this podcast, it is probably safe to assume that you have heard of vaccines and likely are pro-vaccine. But there is a lot of cool science going on under the hood of vaccines! This week on Petri Dish Sean, Nathan, and guest Andrei dig in to the stuff that make up vaccines, the different kinds of vaccines, and whether vaccines are dangerous or not (they aren't, really). This is part 1! In part 2 we talk about how they work on a cell biology level and what next-gen vaccines might look like.

                Featuring a promo for Round & Round The Podcast -- two old Navy buddies shoot the shit on all kinds of topics -- check them out! https://www.rnrthepodcast.com/

                Follow us on twitter @dishpodcast! Email us: petridishpod -at- gmail.com! Check out our patreon page and sign up for as little as $1 a month to help fund us say all these words n stuff www.patreon.com/petridish!

                References:

                • https://www.sciencedirect.com/science/article/pii/S0264410X07002770
                • https://link.springer.com/chapter/10.1007/978-1-4419-1339-5_2
                • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151719/
                • https://www.jstor.org/stable/218112?seq=14
                • https://www.vaccines.gov/basics/types
                • 40 min
                • Ep. 27 Intermittent Fasting: How, What, and Why?
                  Heya folks, today's episode is about intermittent fasting, a new(ish) and increasingly popular way of trying to lose weight. Is it just a fad diet, or something more complicated? How does someone go about doing intermittent fasting and what does it do on a biological level (as far as we know)?As a note: Intermittent fasting involves changing how and when you eat, and therefore is a topic that can be sensitive for those who have eating disorders. If you are concerned about the topic, please feel free to skip the episode and/or contact help, like the free helpline of the National Eating Disorders Association: https://www.nationaleatingdisorders.org/help-support/contact-helpline.Also! Because this topic involves a diet that can impact your health, we want to again mention that this does not constitute medical advice and you should discuss the topic with your doctor first.This week's promo is for the Not Suitable for Adults podcast! Check them out on twitter: @Not4AdultsCast http://not4adultscast.podbean.com/References:https://www.nejm.org/doi/full/10.1056/NEJMra1905136https://www.mdpi.com/2072-6643/11/10/2442/htm https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-071816-064634https://www.annualreviews.org/doi/full/10.1146/annurev-nutr-071816-064916https://www.ncbi.nlm.nih.gov/pubmed/18641044 https://www.ncbi.nlm.nih.gov/pubmed/16647374https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058473/https://www.annualreviews.org/doi/full/10.1146/annurev-pharmtox-010814-12434https://www.cell.com/trends/endocrinology-metabolism/fulltext/S1043-2760(18)30001-8https://link.springer.com/article/10.1007/s13105-018-0658-5https://www.sciencedirect.com/science/article/pii/S1550413117305041https://www.sciencedirect.com/science/article/pii/S089158490600801X?via%3Dihubhttps://www.sciencedirect.com/science/article/pii/S2211124716305769https://www.sciencedirect.com/science/article/abs/pii/S2211034818301421https://www.tandfonline.com/doi/abs/10.1080/030097401750065256https://www.nature.com/articles/cddis201414https://www.cell.com/fulltext/S0092-8674(11)01276-1https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3106288/https://onlinelibrary.wiley.com/doi/full/10.1002/brb3.1444https://www.nature.com/articles/s41467-019-09897-1https://www.frontiersin.org/articles/10.3389/fimmu.2019.01402/fullhttps://pubs.acs.org/doi/abs/10.1021/acs.jproteome.9b00090https://academic.oup.com/ajcn/article/102/2/464/4564588https://www.sciencedirect.com/science/article/pii/S0960982218304433
                  56 min

                About Petri Dish

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                Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy.