Petri Dish

Petri Dish

By Petri DishScienceLife Sciences
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Petri Dish episodes

  • Ep. 119 HIV/AIDS Pt 4: Bone Marrow and Genetic Engineering

    In our final episode in our series on HIV/AIDS, we discuss the cutting edge treatments and vaccines that are currently being tested! One of the treatments discussed even aims to be about as close to a 'cure' as is possible for HIV infection -- learn how they plan to do it!

    References:

    • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4287108/
    • https://www.nytimes.com/2019/03/04/health/aids-cure-london-patient.html
    • https://www.statnews.com/2021/08/31/first-efficacy-trial-of-johnson-johnsons-hiv-vaccine-fails/
    • https://clinicaltrials.gov/ct2/show/NCT05001373
    • https://www.hiv.gov/blog/niaid-and-partners-develop-antibody-based-products-hiv-prevention-and-treatment
    • https://www.hiv.gov/blog/niaid-launches-first-clinical-trial-test-antibody-drug-combination-long-acting-hiv-treatment
    • https://www.nejm.org/doi/full/10.1056/NEJMoa1817426
    • https://www.fiercebiotech.com/biotech/excision-hiv-crispr-gene-editing-therapy-cleared-for-human-studies-by-fda
    • 41 min
    • Ep. 118 HIV/AIDS Pt 3: Current Treatments

      Welcome to part 3 of our series on HIV/AIDS! In the previous two episodes we covered the history of HIV/AIDS and how HIV/AIDS works on the cellular level. In this episode we use that information to understand how our current arsenal of anti-retroviral drugs work! Next week we'll be discussing the treatments on the horizon that may help us reach an end of the HIV/AIDS global epidemic!

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      References:

      https://hivinfo.nih.gov/understanding-hiv/fact-sheets/hiv-treatment-basics

      https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6463712/

      https://www.cdc.gov/hiv/basics/prep.html

      https://www.accessdata.fda.gov/drugsatfda_docs/label/2005/021356s011lbl.pdf

      https://www.aidsmap.com/about-hiv/whats-difference-between-prep-and-pep-hiv-prevention

      https://www.hiv.gov/hiv-basics/hiv-prevention/using-hiv-medication-to-reduce-risk/post-exposure-prophylaxis

      https://i-base.info/guides/starting/can-i-stop-art

      41 min
    • Ep. 117 HIV/AIDS Pt 2: Acute and Chronic

      This week on Petri Dish we dive deeper into HIV/AIDS pathophysiology -- how does HIV do what it does to your body? How does the virus target specific cells? What does it do once it gets into your cells? Definitely an important episode to listen to in order to prep for our next two episodes on current and future treatments!

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      References:

      • https://www.hiv.gov/hiv-basics/hiv-prevention/reducing-mother-to-child-risk/preventing-mother-to-child-transmission-of-hiv
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3543106/
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5526341/
      • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4924471/
      • 33 min
      • Ep. 116 HIV/AIDS: The Present and the Past

        Recent news has led to a lot of excitement with relation to HIV/AIDS -- approval for clinical trials using a new vaccine and a new treatment/potential cure has led to a lot of buzz! But what is the current state of the HIV/AIDS global epidemic? When did HIV first evolve into being? What even is HIV?

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        References:

        https://ourworldindata.org/hiv-aids

        https://www.unaids.org/en/resources/fact-sheet

        https://www.pnas.org/content/117/22/12222

        http://perspectivesinmedicine.cshlp.org/content/1/1/a006841.full

        https://www.who.int/news-room/fact-sheets/detail/hiv-aids

        34 min
      • Ep. 115 COVID Vaccine Booster Shots!

        This week we have a short episode, a Q&A on COVID vaccine booster shots based on the latest info from 09/17/2021! Who can currently get a COVID booster shot? What happened with the FDA recently relating to booster shots? What even is a booster shot? Find out this week!

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        27 min
      • Ep. 114 Strange Medieval Treatments Feat. The Microbe Moment Pt. 2

        It's part 2 of our collaboration with The Microbe Moment (a podcast from The Microbigals! https://www.microbigals.com/the-microbe-moment-science-podcast)!

        We return to our discussion of some of the more ridiculous Medieval treatments for diseases that we could find in our research! Listen in for some of the odder things humans have done to other humans to try to treat a disease!

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        57 min
      • Ep. 113 Strange Medieval Treatments Feat. The Microbe Moment Pt. 1

        In the first episode of our collaboration with The Microbe Moment (a podcast from The Microbigals! https://www.microbigals.com/the-microbe-moment-science-podcast), we discuss some of the more ridiculous Medieval treatments for diseases that we could find in our research! Listen in for some of the odder things humans have done to other humans to try to treat a disease!

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        54 min
      • Ep. 112 Multiple Sclerosis Pt 3: Current and Future Treatments

        In this final episode of our series on Multiple Sclerosis, we discuss the current treatments available for the disease, mainly for the relapsing/remitting form. We then discuss what some of the future treatments look like, including those currently in clinical trials, that may be able to help treat the progressive form of MS!

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        References:

        • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7446632/
        • https://mymsaa.org/ms-information/treatments/long-term/
        • https://pubmed.ncbi.nlm.nih.gov/15089110/
        • https://pubmed.ncbi.nlm.nih.gov/23728638/
        • https://www.nejm.org/doi/full/10.1056/NEJMoa1917246
        • https://onlinelibrary.wiley.com/doi/full/10.1111/ene.13819
        • https://www.sciencedirect.com/science/article/pii/S1474442217302818
        • https://www.nature.com/articles/s41582-018-0082-z
        • https://www.nature.com/articles/nrneurol.2017.81
        • https://www.tandfonline.com/doi/full/10.1080/13543784.2020.1762567
        • https://www.frontiersin.org/articles/10.3389/fmedt.2021.640569/full
        • https://europepmc.org/article/med/33557738
        • https://www.mdpi.com/2227-9059/7/2/26/htm
        • https://academic.oup.com/brain/article/143/12/3574/6012789
        • 56 min
        • Ep. 111 Multiple Sclerosis Pt 2: Missing Myelin

          Last week we started our series on multiple sclerosis by discussing the history of the disease, the symptoms, and the various forms of the disease. This week we dive into the biological cause of the disease. What makes multiple sclerosis pop up? What sorts of genetic or environmental factors seem to play a role?

          We also recommend you check out Eps 63/64 on the blood brain barrier, Eps 56/57 on autoimmune disorders, and Ep 38 on the adaptive immune system for more background information!

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          References:

          • https://www.acpjournals.org/doi/full/10.7326/AITC202106150
          • https://www.sciencedirect.com/science/article/pii/S0896627318300461
          • https://www.nature.com/articles/s41586-018-0842-3
          • 36 min
          • Ep. 110 Multiple Sclerosis Pt 1: Not Scoliosis

            In this week's episode, Nathan and Sean start their discussion of multiple sclerosis, a progressive autoimmune neurodegenerative disorder with a ton of symptoms and freaky way of popping up and disappearing willy-nilly! Learn about Saint Ludwina, the patron saint of ice skaters! Find out what myelin is! Hear acronyms like RRMS! All on this week's episode of Petri Dish!

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            References:

            https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1032909/

            https://www.sciencedirect.com/science/article/abs/pii/S156899721400024X?via%3Dihub

            https://www.newadvent.org/cathen/09233a.htm

            https://onlinelibrary.wiley.com/doi/epdf/10.1111/j.1600-0404.1979.tb02968.x

            https://mymsaa.org/ms-information/overview/history/

            https://journals.lww.com/co-neurology/Fulltext/2018/12000/Multiple_sclerosis__clinical_aspects.15.aspx

            https://www.nationalmssociety.org/What-is-MS/Types-of-MS

            39 min

          About Petri Dish

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          Profane, insane, and 100% primo science, Petri Dish is a no-BS podcast that explores the wildest subjects in modern science with clarity and evil joy.