Philip Marlowe Presented by the Great Detectives of Old Time Radio

Introducing How to lower cholesterol in 10 days | Prof. Sarah Berry from ZOE Science & Nutrition.

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Forty percent of people in the UK and US have high cholesterol. Knowing how to lower it can be confusing. In today’s episode, we simplify the science of cholesterol, drawing from ZOE’s 2021 PREDICT study, which explored its link to the gut microbiome.

Dr. Sarah Berry explains the differences between ‘good’ and ‘bad’ cholesterol, discusses how cholesterol can impact your health, and shares tips on maintaining healthy cholesterol levels.

Sarah is a professor in the Department of Nutritional Sciences at King's College London and Chief Scientist at ZOE. She is also the lead nutritional scientist on the PREDICT program.

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🌱 Try our new plant based wholefood supplement - Daily 30

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

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Timecodes

00:00 Introduction

01:40 Quickfire questions

04:01 What is cholesterol?

05:50 LDL vs HDL cholesterol

11:35 How diet affects cholesterol

13:55 Which fats should you increase?

16:00 Why do some people have high LDL levels?

18:40 The gut microbiome and cholesterol

20:37 What is ApoB?

24:00 Why don’t all doctors measure ApoB?

25:50 Why triglycerides matter to your health

29:30 Triglycerides and post-meal responses

30:45 Which foods can help lower cholesterol?

33:20 Saturated fat explained

35:30 How refined carbs affect cholesterol

39:50 Can you trust ‘low fat’ food labels?

41:15 The benefits of whole grain carbohydrates and fibre

45:03 Sarah’s personal view on statins

48:13 Cholesterol levels in postmenopausal women

Books by our ZOE Scientists:

Free resources from ZOE:

Mentioned in today's episode

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Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing How to Trust and Be Trusted with Rachel Botsman from Revisionist History.

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Rachel Botsman, Oxford University Lecturer and author of the new Pushkin audiobook How to Trust and Be Trusted, joins Malcolm to talk about how to make smart decisions about trust. Then, a preview of How to Trust and Be Trusted, which is available on Spotify, Audible or wherever you get your audiobooks.

See omnystudio.com/listener for privacy information.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing The SB Starter Kit - Everything You Need or Need to Know to Get Your Business Off the Ground (Part 1) - Trademarks, Patents, LLCs and SCorps from Mind The Business: Small Business Success Stories.

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Step one for starting a small business is often coming up with an exciting idea. But what is step two? Step three? Steps four through launch and beyond? On our second episode, and first iteration of our Small Business Starter Kit Series, Austin and Jannese visit The Candle Pour to chat with founders Misty and Dennis Akers. They’ll tell our hosts about how they got their business off the ground and about all the things that go with it: from incorporation to trademarks. Join us as they detail how they went from Grand Idea to Grand Opening. 

Learn more about how QuickBooks can help you grow your business:

Quickbooks.com

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DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing Why 90% of Alzheimer's cases are preventable | Drs. Ayesha and Dean Sherzai from ZOE Science & Nutrition.

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Dementia is one of the fastest-growing health crises in the developed world, with cases expected to double in the coming decades. But despite common misconceptions, cognitive decline isn’t inevitable. The latest research shows that lifestyle choices play a far greater role in brain health than genetics alone.

In this episode, neurologists Drs. Ayesha and Dean Sherzai share practical, science-backed strategies to help you protect your brain and reduce your risk of dementia.

As co-directors of the Alzheimer’s Prevention Program at Loma Linda University, they’ve spent their careers studying how habits like diet, exercise, sleep, and stress management influence long-term cognitive health.

🥑 Make smarter food choices. Become a member at zoe.com - 10% off with code PODCAST

🌱 Try our new plant based wholefood supplement - Daily 30+

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Follow ZOE on Instagram.

Timecodes

00:00 Meet the brain doctors fighting dementia

01:04 Parents have dementia – are you doomed?

02:00 Can dementia be reversed?

02:25 Five lifestyle changes to prevent Alzheimer’s

06:07 What is dementia vs. Alzheimer’s?

08:50 Are your genes to blame?

12:49 Dementia starts 20+ years before diagnosis

14:10 Four biggest causes of Alzheimer’s

19:04 How to build brain reserve & stay sharp

22:50 Are dementia rates rising or falling?

25:30 How the brain declines over decades

29:00 This diet cuts Alzheimer’s risk by 53%

32:40 Three nutrients your brain can’t live without

38:15 The surprising link between LDL cholesterol & dementia

44:10 Leg workouts slash dementia risk by 35%

46:20 Why strength training is critical for brain health

50:36 How stress shrinks your brain

54:00 Sleep: The brain’s natural detox

📚Books by our ZOE Scientists

The Food For Life Cookbook

Every Body Should Know This by Dr Federica Amati

Food For Life by Prof. Tim Spector

Free resources from ZOE

Live Healthier: Top 10 Tips From ZOE Science & Nutrition

Gut Guide - For a Healthier Microbiome in Weeks 

Mentioned in today's episode

Association of Lifestyle and Genetic Risk With Incidence of Dementia, 2019, published in JAMA

Dementia statistics, published by Alzheimer's Disease International (ADI) 

World Alzheimer Report 2015 - The Global Impact of Dementia, published by Alzheimer's Disease International (ADI) 

Midlife serum cholesterol and increased risk of Alzheimer's and vascular dementia three decades later, 2009, published in Dementia and Geriatric Cognitive Disorders 

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].

Introducing Stop dementia before it starts from ZOE Science & Nutrition.

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How early should you start taking dementia seriously?

Here’s 5 things you can do now to reduce dementia risk today.

Professor Claire Steves and Jonathan Wolf explore the multifaceted world of dementia. They delve into the significance of dental health, genetics, diet, and physical activity — plus, they unpack the latest research — to give you practical strategies for preventing dementia.

Claire is a consultant physician in geriatric medicine at Guy's and St Thomas' NHS Foundation Trust. She’s also a senior clinical lecturer at King's College London and deputy clinical director of the institution’s Department of Twin Research and Genetic Epidemiology where she leads research on the characterization of physical and mental aging traits and frailty.

🌱 Try our new plant based wholefood supplement - Daily 30

*Naturally high in copper which contributes to normal energy yielding metabolism and the normal function of the immune system

Learn how your body responds to food 👉 zoe.com/podcast for 10% off

Follow ZOE on Instagram.

Timecodes:

00:00 - Introduction

01:26 - Quickfire questions on dementia

02:42 - Main discussion: understanding dementia

04:18 - Control over fate with dementia

06:52 - Why older people get more fractures

08:32 - Warning signs of dementia

09:55 - Unique aspects of dementia

12:12 - Cellular level discussion on dementia

15:49 - Risk factors for dementia

16:07 - Inheritance and dementia

18:29 - High-risk factors for dementia

19:15 - Fetal development and dementia risk

21:47 - Brain reserves and mental health

24:24 - New advances in dementia treatment

30:47 - Medications and life expectancy

33:21 - Diet and dementia prevention

35:58 - The role of physical activity

39:45 - Oral health and dementia

42:10 - Social interaction and brain health

44:02 - Diabetes and dementia

45:36 - Women, HRT, and dementia

49:09 - Recap: Types of dementia

53:39 - Hearing aids and dementia prevention

55:39 - Episode sign-off

Studies related to today’s episode:

Find our top 10 tips for healthier living: Download our FREE guide.

Have feedback or a topic you'd like us to cover? Let us know here.

Episode transcripts are available here.

DISCLAIMER: Please note, this is an independent podcast episode not affiliated with, endorsed by, or produced in conjunction with the host podcast feed or any of its media entities. The views and opinions expressed in this episode are solely those of the creators and guests. For any concerns, please reach out to [email protected].