🍐 In this true-crime–themed episode of PodBites, Abdulrahman Aldahash and Amro Badra transform hemolytic anemias into a detective story — chasing down the culprits behind the premature “murder” of red blood cells.
🎙️ Tune in to learn about:
Intrinsic vs. extrinsic hemolysis — the “inside job” vs. the “outside assault”Classic lab clues: ↑ indirect bilirubin, ↑ LDH, ↓ haptoglobin, ↑ reticulocytesExtravascular vs. intravascular hemolysisHereditary Spherocytosis & Elliptocytosis — membrane defects, spherocytes, MCHC rise, diagnostic testsG6PD Deficiency — oxidative stress, Heinz bodies, bite cells, triggers & timing of testingWarm & Cold Autoimmune Hemolytic Anemia — IgG vs. IgM, DAT interpretation, treatment differencesTTP & HUS — schistocytes, microangiopathic clues, ADAMTS13, Shiga toxin, kidney vs. brain involvementParoxysmal Nocturnal Hemoglobinuria (PNH) — PIGA mutation, complement sensitivity, dark urine at night, eculizumabHigh-yield comparisons, memory tricks, and case-based reasoning throughout🔍 A cinematic, high-yield exploration of every major cause of hemolytic anemia — taught through mystery, humor, and detective-style logic that makes the content unforgettable.