Precision Medicine Made Simple

Precision Medicine Made Simple

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Precision Medicine Made Simple episodes

  • The Hardest Part of Longevity Medicine According to This Stanford Doctor

    What if your doctor could predict what will kill you—before it ever becomes a problem? In this episode of Precision Medicine Made Simple, we dive into the evolving landscape of longevity medicine and health AI with Dr. Hillary Lin, Stanford-trained internist, former oncologist, and co-founder of CareCore—a platform empowering wellness creators and brands to offer doctor-supervised, data-driven care.

    Dr. Lin shares her personal journey from frustration with traditional medicine to building one of the most forward-thinking longevity platforms today. She discusses how we can sift through misinformation, integrate wearables, genetics, and proteomics, and balance the promise of AI with the human art of medicine.

    If you're interested in the intersection of tech, behavior change, and personalized healthcare—or you're a clinician navigating this fast-changing world—this episode is a must-listen.

    Key Takeaways
    • Why Dr. Lin walked away from oncology—and what that revealed about the limits of traditional medicine
    • How AI is helping doctors make sense of overwhelming health data (without replacing the human touch)
    • Why behavior change—not biomarkers—is still the hardest challenge in longevity care
    • What whole genome sequencing and proteomics are uncovering about health risk (and why family history still matters)
    • How mental health is shaped by biology, not just emotions—and what that means for future treatments
    • Why “more data” isn’t always better—and how the art of medicine guides what we actually do with it
    • How CareCore is bringing doctor-backed longevity tools to wellness creators, gyms, and health brands
    • Why longevity medicine must balance innovation with scientific rigor—and where influencers can help or hurt

    In This Episode
    • [00:00] Dr. Lin’s background and intro to the show
    • [01:02] Leaving traditional medicine: oncology frustrations
    • [07:07] Curiosity, questioning incentives, and systemic change
    • [14:30] Wearables, data overwhelm, and near-future care
    • [19:21] Will AI replace doctors? Not likely—here’s why
    • [25:27] Behavior change, accountability, and lifestyle compliance
    • [28:40] Why common advice still matters—but needs personalization
    • [32:56] Dr. Lin’s take on Brian Johnson’s biohacking movement
    • [36:33] The importance of community and mental health in longevity
    • [43:39] Gut-brain connection and biological drivers of mental health
    • [47:01] How to build a personalized longevity baseline
    • [50:23] Genomics vs. real-world outcomes: a case study in family history
    • [55:44] AI-enabled care and the future of CareCore
    • [59:20] Influencer health, B2B partnerships, and responsible content

    Notable Quotes
    • [01:02] "I realized somewhere along the way that I couldn't be a doctor in today's system and do the things that I hope to do. You have to maintain the mind of a child always in that you're asking why?" — Dr. Hillary Lin
    • [01:38] "Behavior change is the number one, most important and hardest thing to achieve. I think the art part of medicine is really knowing what to do with incomplete knowledge." — Dr. Hillary Lin
    • [08:09] "The curiosity was so important because it makes you push past a lot of deterrence... you have to really dig past that by continuously asking, well, why is it that way?" — Dr. Hillary Lin
    • [21:46] "I think there will always be a place for doctors slash healers. And the reason is humans love other humans." — Dr. Hillary Lin
    • [29:48] "I think the art part of medicine is really knowing what to do with incomplete knowledge.I always say start with figuring out what will kill you first.”— Dr. Hillary Lin
    • [34:55] "I think people should be re-energized about lifestyle changes. It's not new, but if he makes it seem like it's new, then cool, that's fine." — Dr. Hillary Lin
    • [55:59] "We are going to almost fully automate healthcare in the future, starting with the lower risk fields of course." — Dr. Hillary Lin


    Our Guest

    Hillary Lin, MD is the Co‑Founder & CEO of Care Core, a clinical platform that empowers wellness creators and brands to offer doctor‑supervised lab tests, prescriptions, and evidence‑based health products.

    A Stanford‑trained internist with oncology experience at Columbia, she previously co‑founded Curio, a venture‑backed digital‑mental‑health platform.

    Dr. Lin is an Aspen Health Fellow and advisor to innovation hubs at Stanford and Cornell, along with select health and longevity startups.

    Through YouTube, LinkedIn, Instagram, TikTok (@hillarylinmd), her newsletter The Long Game, and the podcast The Longevity Show, she shares practical longevity science to help people extend their healthspan.

    Resources and Links

    Dr. Hillary Lin

    • https://www.linkedin.com/company/carecore
    • https://www.hillarylinmd.com/
    • https://www.linkedin.com/in/hillarylinmd
    • https://podcasts.apple.com/us/podcast/the-longevity-show-with-dr-hillary-lin/id1760084330
    • https://www.hillarylinmd.com/subscribe
    • https://www.youtube.com/@hillarylinmd

    Taylor Cu

    • https://precision-medicine-made.captivate.fm/
    • https://www.linkedin.com/in/taylorcu
    • https://www.instagram.com/taylor_cu
    • LinkedIn
    • Instagram

    Dr. William Stanford

    • https://www.linkedin.com/in/william-stanford-md-phd-facp


    Sponsored by: Biography Health

    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.


    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.


    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    1 hr 4 min
  • The Side of Personalized Healthcare No One Talks About

    In this episode of Precision Medicine Made Simple, hosts Dr. William Stanford and Taylor Cu sit down with Dr. Genise Fraiman, founder of Ascending Medicine and a trailblazer in concierge care. With over two decades of experience—from co-founding one of Cedars-Sinai’s top hospitalist groups to mentoring young physicians—Dr. Fraiman shares her personal and professional evolution toward a more human, proactive approach to medicine.

    Together, they unpack the pressures of traditional practice, the emotional toll of hospital work, and Dr. Fraiman’s  deeply personal experience navigating breast cancer risk without the genomic tools we now have at our fingertips. She also reveals how treating sleep apnea transformed her own health—and why even “healthy” patients shouldn’t ignore it.

    This candid, wide-ranging conversation explores the promise (and pitfalls) of AI in healthcare, the art of vetting medical information, and what it really takes to start a concierge or precision-focused practice today. At its core, this episode is about reimagining the doctor-patient relationship—and reclaiming time, trust, and tailored care.

    Key Takeaways
    • The untold toll of hospital-based medicine—and why Fraiman finally left it behind
    • What concierge care actually looks like in practice (and why it matters)
    • Why time is the most underrated tool in patient care
    • Dr. Fraiman’s decision to undergo a prophylactic mastectomy—and the missing genomic data that could’ve changed it all
    • How sleep apnea affects even lean, fit patients—and how CPAP changed her health
    • What patients should know about supplements, pseudoscience, and AI misinformation
    • How to vet a personalized medicine provider—and why the right “fit” matters more than ever
    • Dr. Stanford’s bold prediction: commercial health insurance will collapse within 10 years


    In This Episode
    • [00:00] Introduction and initial questions
    • [00:59] Welcome to the podcast
    • [01:07] Guest introduction: Dr. Genise Fraiman
    • [01:55] Early career and meeting Dr. Stanford
    • [04:07] Building a hospitalist group
    • [04:34] Transition to concierge medicine
    • [05:52] Challenges and rewards of concierge medicine
    • [07:13] Personalized patient care
    • [13:50] Proactive vs. reactive medicine
    • [19:47] Personal health journey and genetic risks
    • [29:48] Sleep study reflections
    • [30:11] Challenges and adjustments with CPAP
    • [31:21] Exploring alternative treatments
    • [33:00] Navigating medical information and supplements
    • [38:02] The role of AI in healthcare
    • [42:44] Starting a concierge medical practice
    • [46:58] Insurance and healthcare costs
    • [52:32] Privacy concerns with genetic testing
    • [55:28] Finding the right medical provider
    • [57:42] Conclusion and contact information


    Notable Quotes
    • [07:28] "What I found is I've been on all sides. I've been the patient, I've been the physician, I've been the family member. And it's a really horrible feeling to feel helpless in any of those situations."— Dr. Genise Fraiman


    • [14:33] “I think we were taught to be really great at being reactive physicians. But if we can take that same knowledge and be proactive—change the trajectory—that’s the name of the game.” — Dr. Genise Fraiman


    • [24:53] “If I had the genetic information then that I have now, the decision around my mastectomy would’ve been far less agonizing.” — Dr. Genise Fraiman


    • [27:50] “I failed my sleep study miserably… and I’m 5’3”, fit, and healthy. You can’t ignore the data.” — Dr. Genise Fraiman



    Our Guest Dr. Genise Fraiman

    Founder of Ascending Medicine, Dr.Fraiman  brings over two decades of clinical leadership, including founding a leading hospitalist group at Cedars-Sinai and transitioning to concierge and precision medicine. A recognized advocate for truly patient-centered care, she is passionate about longevity, genomics, and building meaningful doctor-patient relationships that last.


    Resources and Links


    Dr. Genise Fraiman

    • https://www.ascendingmedicine.com/
    • https://www.linkedin.com/in/genise-fraiman-41a56288/



    Taylor Cu

    • https://precision-medicine-made.captivate.fm/
    • https://www.linkedin.com/in/taylorcu
    • https://www.instagram.com/taylor_cu


    Dr. William Stanford


    • https://www.linkedin.com/in/william-stanford-md-phd-facp



    Sponsored by: Biography Health


    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.


    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.


    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    54 min
  • This Ex-Surgeon Is Reprogramming Aging with AI and Systems Science

    We’re living in the age of health data overload—but how do you turn all those insights into real-life transformation? This episode of Precision Medicine Made Simple features Dr. Daniel Stickler, former vascular surgeon turned systems medicine pioneer, who’s leading the charge in longevity, AI-powered diagnostics, and cutting-edge clinical tools.

    In this candid conversation with hosts Dr. Stanford and Taylor, Dr. Stickler opens up about the moment he walked away from surgery for good—and how it led to building an entirely new model of medicine. From continuous glucose monitors to full genome sequencing, from peptides to personalized AI agents, Dr. Stickler shares the emerging tools that are empowering both doctors and patients to move from disease management to proactive health optimization.

    Whether you're a healthcare provider, tech innovator, or simply a wellness-curious listener, this episode will challenge your assumptions and give you a vision for the future of truly personalized care.

    Key Takeaways
    • Why most modern medicine is built around postponing death, not optimizing life
    • How wearables like Garmin and UltraHuman reveal individual patterns (and change behavior fast)
    • The overlooked power of epigenetics—and why lifestyle still rules your genes
    • What peptides like BPC-157 and GLP-1 analogs are doing for healing, inflammation, and gut health
    • How Dr. Stickler uses AI to process patient data and create 50-page system-based care plans in minutes
    • Why “root cause” medicine might be an outdated myth—and what’s next


    In This Episode
    • [00:00] Introduction 
    • [00:14] Guest introduction: Dr. Daniel Stickler
    • [01:00] Dr. Stickler's journey into medicine
    • [03:19] Integrating wearable technology in medicine
    • [05:39] The impact of wearables on patient care
    • [12:38] Genetics and epigenetics in medicine
    • [22:21] Systems-based medicine explained
    • [27:08] The role of peptides in modern medicine
    • [30:58] Introduction to GLP-1 peptides
    • [31:30] Benefits and fine-tuning of semaglutide
    • [32:35] Exploring BPC-157 for recovery
    • [33:51] Oral vs. injectable BPC-157
    • [35:05] Potential downsides of BPC-157
    • [36:44] Wearable technology and recovery
    • [38:19] The future of medicine: AI and personalized care
    • [56:17] The role of physicians in the AI era
    • [57:17] Concerns about over-reliance on technology
    • [58:46] Recommended resources for providers and patients
    • [01:01:19] FDA's role in approving medical advancements
    • [01:03:42] Exosomes and young plasma therapy potential


    Our Guest

    Dr. Daniel Stickler is the Co-Founder and Chief Medical Officer of Apeiron Zoh and Mosaic Biodata, where he integrates wearable tech, AI, peptides, genetics, and systems thinking into personalized healthcare. A former high-volume surgeon, he now trains clinicians globally in longevity and performance medicine. He's also an advisor to Google and a recognized thought leader in human enhancement and optimization.


    Resources and LinksDr. Daniel Stickler
    • Apeiron Center
    • LinkedIn
    • Substack


    Taylor Cu
    • Captivate.FM
    • LinkedIn
    • Instagram


    Dr. William Stanford
    • LinkedIn


    Sponsored by: Biography Health


    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.

    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.

    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    54 min
  • The Former ER Doctor Challenging How We Practice Medicine w/Dr. Sukhjit "Sarge" Takhar

    The Former ER Doctor Challenging How We Practice Medicine w/Dr. Sukhjit "Sarge" Takhar

    Primary-MD.com

    Email: [email protected]

    Takeaways

    • Dr. Takhar emphasizes the importance of understanding the patient as a person.
    • Concierge medicine allows for more personalized and attentive care.
    • The healthcare system often limits the time doctors can spend with patients.
    • AI can assist in healthcare but cannot replace the human connection.
    • Precision medicine focuses on individual patient needs rather than population averages.
    • The integration of advanced diagnostics is crucial for effective patient care.
    • Healthcare professionals must navigate the challenges of the current system.
    • There is a growing need for democratization of advanced medical care.
    • Patients should be encouraged to take an active role in their health decisions.
    • The future of medicine will likely involve more personalized and preventive approaches.

    Summary

    In this episode of the Precision Medicine Made Simple podcast, hosts Taylor Cu and Dr. William P. Stanford engage with Dr. Sukjit "Sarge" Takhar, a pioneer in concierge medicine. They discuss the evolution of healthcare, the challenges faced by practitioners, and the importance of personalized patient care. Dr. Takhar shares his journey from traditional medicine to a more individualized approach, emphasizing the role of advanced diagnostics and the integration of AI in healthcare. The conversation highlights the need for a human connection in medicine, the significance of understanding patient backgrounds, and the future of precision medicine as it becomes more accessible and affordable. The episode concludes with advice for aspiring medical entrepreneurs and a discussion on the intersection of science and patient care.

    Chapters

    00:00 The Journey Begins: Personal Stories and Connections

    02:32 From Traditional Medicine to Concierge Care

    06:36 The Shift Towards Precision Medicine

    10:50 Challenges and Opportunities in Healthcare

    14:57 The Future of Health Monitoring and Diagnostics

    25:57 Vitalist Bay: A Progressive Longevity Conference

    26:23 Buyer Beware: Navigating Longevity Medicine Hype

    27:37 Understanding Conflicts of Interest in Longevity Research

    28:30 Metabolic Health: The Crisis and Its Implications

    29:57 The Role of Direct-to-Consumer Tests in Health Decisions

    31:42 Precision Medicine: Personalizing Health Strategies

    33:21 AI in Medicine: The Human Advantage

    35:33 The Evolution of AI in Healthcare

    37:31 AI and Human Connectivity in Medicine

    39:58 The Future of AI in Patient Care

    47:53 Navigating AI Regulations in Healthcare

    50:33 Advice for Aspiring Medical Entrepreneurs

    51:19 The Challenges of Building a Practice

    53:00 Staying Current in Medicine

    56:20 The Importance of Precision Medicine

    01:01:25 Personalized Health Recommendations

    01:07:55 Building Trust with Patients

    01:13:43 Navigating the Landscape of Health Claims

    01:16:14 PMMS - New Outro - No Music.mp4

    Dr. William Stanford MD PHD FACP

    [email protected]

    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Institute for Precision Medicine, enhancing his role as a leading expert in the field.

    Sponsored by: Biography Health

    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.

    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.

    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    Keywords

    Precision Medicine, Concierge Medicine, Healthcare Innovation, Patient Care, AI in Medicine, Health Coaching, Genetic Testing, Personalized Medicine, Medical Entrepreneurship, Longevity

    1 hr 17 min
  • The Doctor Who Says Dialysis Is Preventable w/ Dr. David Moskowitz

    In this episode, Dr. David Moskowitz shares how thousands of patients have avoided dialysis through genomic medicine — and why most kidney failure is preventable.

    We dive deep into ACE genes, repurposed drugs like quinapril and ProGraph, and explore what genomic insights could mean for diseases like Alzheimer's and cancer.

    Heads up: this one gets detailed with a lot of medical terminology. If you're curious but lost, drop the transcript into ChatGPT — it'll help translate the science.

    Dr. David Moskowitz - genomed.com

    Takeaways

    Dialysis is preventable, and awareness is crucial.

    Innovative approaches can challenge traditional medical practices.

    ACE inhibitors should be the first line of defense in kidney health.

    Genetic factors play a significant role in Alzheimer's disease.

    Whole genome sequencing can provide insights into various diseases.

    Repurposing existing drugs may offer new treatment avenues.

    The healthcare system often resists change due to financial incentives.

    Public health initiatives need to focus on improving outcomes.

    Understanding the molecular basis of diseases can lead to better treatments.

    Collaboration and communication in medicine are essential for progress.

    Chapters

    00:00 Introduction to Preventive Medicine and Genomics

    04:53 The Journey to Preventing Kidney Disease

    07:35 Innovations in Kidney Health: The Role of ACE Inhibitors

    10:14 Challenges in the Healthcare System

    12:45 The Impact of Lifestyle on Kidney Health

    15:38 Exploring the Connection Between COVID-19 and Kidney Disease

    17:50 The Future of Genomics in Preventive Medicine

    20:10 Patient Empowerment and Navigating Healthcare

    22:57 Key Takeaways

    39:31 Exploring Whole Genome Sequencing in Alzheimer's

    42:16 Iron Overload and Neurodegeneration

    46:36 mTOR Pathway and Alzheimer's Treatment

    48:29 Repurposing Drugs for Alzheimer's and Other Neurodegenerative Diseases

    55:09 Genetic Risk Factors for Alzheimer's

    57:00 Innovations in Cancer Detection

    01:02:47 Differentiation Therapy in Cancer Treatment

    01:08:38 The Importance of Personalized Health

    Dr. William Stanford MD PHD FACP

    [email protected]

    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Institute for Precision Medicine, enhancing his role as a leading expert in the field.

    Sponsored by: Biography Health

    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.

    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.

    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    1 hr 9 min
  • What Jensen Huang Got Right About the Future of Healthcare w/Lucy Janoyan

    In this episode, Dr. Stanford, Lucy Janoyan, and Taylor Cu reflect on key takeaways from the Precision Medicine World Conference — from AI’s role in understanding disease to the future of polygenic risk scores. They discuss the challenges of data validity, patient privacy, and the evolving role of patients and providers in a tech-driven healthcare landscape, including a highlight from NVIDIA CEO Jensen Huang on how AI is set to reshape the future of medicine.

    Takeaways

    The conversation around precision medicine has evolved significantly since 2019.

    AI is transforming patient care and the practice of medicine.

    The PMWC provided a more intimate setting for meaningful discussions.

    There is a growing concern about the ethical implications of AI in healthcare.

    The transition from research to clinical practice is crucial for precision medicine.

    Economic factors play a significant role in the adoption of precision medicine.

    Digital twins could revolutionize personalized healthcare.

    Data privacy and patient ownership are critical issues in genomic sequencing.

    The insurance industry faces challenges in adapting to precision medicine.

    The future of healthcare will be dramatically different in the next decade.


    Chapters


    00:00 Introduction to Precision Medicine and Conference Insights

    05:22 Evolution of Precision Medicine Discussions

    08:30 AI's Role in Healthcare Transformation

    11:35 Challenges in Data Validity and Clinical Adoption

    14:17 The Future of Polygenic Risk Scores

    17:27 Optimism vs. Pessimism in Precision Medicine

    20:26 Insurance and Healthcare Delivery Paradigms

    23:31 Digital Twins and Their Impact on Precision Medicine

    41:44 The Future of AI in Medicine

    44:56 Understanding Aging and Disease Pathways

    46:54 The Role of AI in Autonomous Science

    48:40 Holistic and Precision Medicine

    52:49 Data Privacy and Patient Governance

    56:55 Concerns Over Genome Sequencing

    01:02:13 The Global Landscape of Genomic Data

    01:05:42 The Democratization of Precision Medicine

    01:43:32 Introduction to Precision Medicine

    01:43:32 The Importance of Personalized Health


    Dr. William Stanford MD PHD FACP

    [email protected]

    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Institute for Precision Medicine, enhancing his role as a leading expert in the field.


    Sponsored by: Biography Health


    This episode is sponsored by Biography Health — where DNA-powered healthcare is designed just for you. Biography Health is a HIPAA-compliant precision medicine platform that equips providers with AI-driven recommendations powered by your genetics, health history, and clinical insights — all while keeping data private, secure, and independent from large EHR systems.


    If you're a provider ready to bring precision medicine into your practice, visit BiographyHealth.com to learn more.


    Or, if you're a patient who wants your doctor to explore this, point them our way — we’ll help them bring personalized healthcare to life.

    58 min
  • When Genes Collide: A Rare Diagnosis Reveals Complex Health Interactions with Dr. Philip Bretsky

    When Genes Collide: A Rare Diagnosis Reveals Complex Health Interactions with Dr. Philip Bretsky

    For this episode, Dr. Bretsky shares a remarkable case study that unravels the complex relationship between genes and inflammation. When a patient's mysterious symptoms led to the rare diagnosis of VEXAS syndrome, it revealed an unexpected connection with cardiovascular health, demonstrating how different genetic factors can interact to amplify health risks.


    Timestamps:


    • 3:50 - Introduction to Lp(a) and its role in cardiovascular health
    • 10:09 - Patient's initial presentation with testicular swelling
    • 17:55 - Discussion of environmental factors and genetic mutations
    • 23:28 - Understanding inflammation's role in cardiovascular risk
    • 35:32 - Treatment decisions and stent placement
    • 41:51 - Prevention strategies for inflammatory conditions
    • 1:24:19 - Episode wrap-up and closing


    Dr. Philip Bretsky's Contact Information:

    Philip M. Bretsky MD PhD MPH FACP

    1301 20th Street, Suite 230

    Santa Monica, CA 90404

    TEL: 310.828.4411

    FAX: 310.828.2411

    Facebook:@santamonicaprimarycare

    Twitter / X: @santa_care

    Instagram: @santa_monica_primary_care

    Web:  www.drbretsky.com & www.santamonicaprimarycare.com

    My monthly newsletter: https://lp.constantcontactpages.com/su/JtF9zzR


    Dr. William Stanford MD PHD FACP

    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills Institute for Precision Medicine, enhancing his role as a leading expert in the field.

    Sponsored by: Biography Health

    Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.


    Other Resources Mentioned:

    https://www.cnn.com/2023/01/24/health/vexas-syndrome-prevalence-study-wellness/index.html


    https://www.amazon.com/Implementation-Personalized-Precision-Medicine-Prevention/dp/0323988083

    1 hr 25 min
  • Beauty Span and Health Span: Where Aesthetics Meets Longevity with Dr. Cory Goldberg

    Beauty Span and Health Span: Where Aesthetics Meets Longevity with Dr. Cory Goldberg

    For this episode, we dive deep into the intersection of aesthetics and longevity with Dr. Cory Goldberg, a renowned plastic and craniofacial surgeon. Dr. Goldberg bridges the art of aesthetic medicine with the science of precision medicine, sharing groundbreaking insights on how oxidative stress affects both beauty and overall health, and discussing innovative approaches to extending both beauty span and health span.


    Timestamps:

    03:27:24 - Dr. Goldberg shares his background and journey from physiology to plastic surgery to precision medicine

    23:31:24 - Deep discussion on senescent cells (zombie cells) and their impact on aging and health

    35:13:13 - Exploration of the gut-skin-brain axis and microbiome connections

    43:51:24 - Detailed explanation of reactive oxygen species (ROS) and their role in aging

    57:46:07 - Discussion of GliSODin supplement and superoxide dismutase

    1:18:52:13 - Dr. Goldberg's insights on diet, plant-based eating, and oxidative stress

    1:27:27:15 - Overview of Dr. Goldberg's practice evolution and his vision for integrating longevity medicine with aesthetic medicine




    Dr. Cory Goldberg

    https://www.linkedin.com/in/corygoldbergmd/

    https://www.corygoldbergmd.com/

    https://www.instagram.com/drcorygoldbergmd/


    Dr. Cory S. Goldberg BSc, MD, MASc, FRCS(C), FACS, MBA is a Plastic Surgeon with a fellowship in the Royal College of Physicians and Surgeons of Canada. 

    He is a diplomat of the American Board of Plastic Surgeons and is also a Fellow of the American College of Surgeons. He earned his MD degree from Queen’s University, Canada and completed his Plastic Surgery residency training at the University of Toronto, including a Master’s of Applied Science in Biomedical Engineering. He subsequently did sub-specialty fellowship training in Craniofacial Plastic Surgery at University of Southern California in Los Angeles, California.




    Dr. William Stanford MD PHD FACP

    [email protected]


    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills


    Sponsored by: Biography Health

    Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.

    1 hr 33 min
  • From Flight Medic to Precision Medicine with Dr. Kat Schmolly

    From Flight Medic to Precision Medicine with Dr. Kat Schmolly

    In this episode, we're joined by Dr. Kat Schmolly. From her adventurous past as an Air Force Flight Medic to her current mission revolutionizing rare disease diagnosis, Dr. Schmolly shares her unique journey into precision medicine. We discuss why bringing personalized care to the frontlines of medicine is crucial, and explore how innovative technologies can transform the future of healthcare.


    Timestamps:


    2:58 - How Dr. Schmolly and Dr. Stanford connected over precision medicine

    7:35 - Early observations of environmental impacts on military health

    13:22 - The near-disaster flight mission that changed her path

    26:43 - Why precision medicine stays in research vs clinical practice

    43:58 - Starting ZebraMD to transform rare disease diagnosis

    47:19 - Vision for bringing precision medicine to primary care


    Dr. Kat Schmolly

    linkedin.com/in/kat-schmolly

    [email protected]


    Dr. Kat Schmolly is a physician at Dartmouth Health, combining her clinical expertise with a passion for advancing personalized medicine. As the founder of ZebraMD, she focuses on innovative solutions for rare disease diagnostics through algorithm development and AI-powered clinical tools. A graduate of the David Geffen School of Medicine at UCLA, her work has included groundbreaking research in genetic and rare diseases.

    Before pursuing medicine, Dr. Schmolly served as a flight medic in the United States Air Force, where she honed her skills in aerospace and critical care medicine. With experience ranging from cardiac R&D at Medtronic to porphyria research and precision medicine development, Dr. Schmolly continues to lead efforts that bridge cutting-edge technology with patient-centered care.



    Dr. William Stanford MD PHD FACP

    [email protected]


    Dr. William Stanford is co-founder of Biography Health. He began his career as a mechanical and aerospace engineer at Texas Instruments in 1982 while also pursuing his interest in aviation as a flight instructor and commercial pilot. In 1991, he pivoted into biomedical science and subsequently completed the combined M.D./Ph.D. physician-scientist training program at the University of California, Los Angeles, in 1998 and an internal medicine residency at UCLA in 2001. He is board-certified in internal medicine and is a Fellow of the American College of Physicians.

    A pioneer in the field of hospital medicine, Dr. Stanford founded and led a 25-physician group of private practice hospitalists at Cedars-Sinai Medical Center in Los Angeles in 2002. After an extensive clinical career as the attending physician for over 100,000 patients, he was elected by his peers at Cedars-Sinai to be clinical chief of general internal medicine, serving in this capacity from 2017 to 2018. Inspired by recent advancements in biomedical science and medicine, Dr. Stanford completed professional certification through Stanford University’s Department of Genetics in 2018, further advancing his role as a true physician-scientist. Since 2018, he has provided genomic and precision medicine consultations through the Beverly Hills


    Sponsored by: Biography Health

    Biography Health, where healthcare meets personalization. With their DNAbled™ Blueprint, Biography Health empowers you with a health plan based on your unique DNA, aiming to prevent disease and extend your life. Take control of your health journey with a plan as unique as you. Visit BiographyHealth.com and start your personalized healthcare journey today.

    1 hr 3 min

About Precision Medicine Made Simple

From the publisher's feed

Welcome to the “Precision Medicine Made Simple Podcast,” where we simplify the complex world of precision medicine. We're here to explore how personalized healthcare can empower you to understand and improve your health to live a longer and healthier life. Join us as we break down the latest in medical science into actionable insights. Let's make precision medicine accessible and actionable for everyone.