Proactive - Interviews for investors

Sona Nanotech Inc (CSE:SONA, OTCQB:SNANF) chief medical officer Dr Carman Giacomantonio joined Steve Darling from Proactive to discuss the company's innovative targeted hyperthermia technology for cancer treatment. This cutting-edge approach utilizes gold nanoparticles activated by near-infrared light to heat tumor tissue to a controlled temperature range of 42–48°C, selectively stressing cancer cells while preserving healthy tissue.

Dr. Giacomantonio explained that this method has the potential to trigger immune system activation, effectively converting "cold tumors" (which do not naturally provoke immune responses) into "hot tumors" that do. Sona Nanotech has already demonstrated this effect in colon cancer and is now expanding its research into brain cancer.

The company's findings were recently published in Frontiers in Immunology, a respected peer-reviewed journal, further validating its approach. Dr. Giacomantonio emphasized that this scientific recognition not only strengthens the credibility of Sona’s technology but also opens doors for potential industry collaborations.

Looking ahead, Sona Nanotech is preparing to launch a clinical trial to assess the feasibility and safety of this approach in humans. The ultimate goal is to develop a practical, minimally invasive cancer treatment that eliminates the need for complex surgical procedures.

#proactiveinvestors #sonananotechinc #cse #sona #otcqb #snanf #CancerTreatment #MedicalInnovation #HyperthermiaTherapy #GoldNanoparticles #Immunotherapy #TargetedTherapy #CancerResearch #Biotech #MedicalBreakthrough

C3 Metals CEO Dan Symons joined Steve Darling from Proactive to announce significant gold results from soil and channel sampling at the company’s 50%-owned Super Block project in Jamaica.

C3 Metals operates the project under a 50/50 joint venture with Geophysx Jamaica.

Symons explained that the Super Block project spans 9,870 hectares, located west of C3 Metals’ Arthurs Seat and Bellas Gate projects. The project is strategically positioned near Barrick Gold’s mineral concessions, where Barrick holds the right to earn an 80% joint-venture interest with Geophysx.

Recent closely spaced soil and channel sampling at Super Block has confirmed strong gold geochemistry along a trend comparable in intensity to the former Pennants Gold Mine, which historically produced 16,000 ounces of gold between 2002 and 2004. Geochemical sampling identified highly anomalous gold over a +5km strike northwest and southeast of the Pennants Gold Mine, where historical resources were reported at 20.4 g/t gold.

C3 Metals has designed an initial 2,500-metre diamond drilling program comprising 14 holes to test the gold and coincident radiometric anomalies. The company is in the process of applying for drill permits for the remaining areas of the PEZ prospect and Pennants regions and plans to conduct additional surface exploration through soil and channel sampling to the east and north of the PEZ prospect.

#proactiveinvestors #c3metalsinc #tsxv #cccm #otcqb #cuauf #GoldExploration #MiningStocks #JamaicaMining #GoldInvesting #JuniorMining #DrillProgram #Geophysics #BarrickGold #MiningNews

Bitwise Asset Management European head Bradley Duke takes Proactive's Stephen Gunnion through recent developments in the US crypto landscape under the Trump administration. Duke noted key policy changes, including the appointment of David Sacks as "crypto czar" and an executive order rejecting a US central bank digital currency (CBDC). He also highlighted new regulatory focus on stablecoins and adjustments to US accounting policies that benefit crypto investors.

Duke discussed the creation of a US sovereign wealth fund aimed at investing in Bitcoin and other cryptocurrencies, a move that could drive long-term institutional adoption. He pointed out that 22 US states have already expressed interest in holding Bitcoin in their treasuries.

On market trends, Duke explained that Bitcoin has been trading around the $100,000 mark, with some price fluctuations linked to broader economic concerns, including US-China trade tensions. He noted that a strong US dollar has historically acted as a headwind for Bitcoin, while decreasing exchange balances indicate bullish sentiment.

Looking ahead, Duke mentioned that last year's Bitcoin halving event could significantly impact supply and prices. He also welcomed BlackRock’s entry into the European crypto exchange-traded product market, stating that competition drives innovation and market growth.

Watch the full interview to gain more insights. Don’t forget to like this video, subscribe to our channel, and enable notifications for future updates.

#Bitcoin #CryptoMarkets #Bitwise #BradleyDuke #CryptoRegulation #TrumpCrypto #Stablecoins #BitcoinHalving #CryptoNews #DigitalAssets

Xeros Technology Group PLC (AIM:XSG) CEO Neil Austin takes Proactive's Stephen Gunnion through the company’s latest trading update and key strategic developments. He highlighted that Xeros is currently engaged in a tech verification process with four of the world's top ten washing machine manufacturers, moving closer to potential joint venture agreements (JVAs) and commercialisation in early 2026.

Austin also discussed a letter of intent with a global consumer electronics brand for Xeros’ XF3 external microfiber filter technology. He noted that 35% of microplastic pollution in the ocean originates from the laundry process, and Xeros’ solutions aim to significantly reduce this impact.

Additionally, Xeros is progressing in the garment manufacturing sector, working with Yilmak Makina, a leading denim processing company. The partnership is expected to help commercialise Xeros' Finish technology, further expanding the company’s reach.

Austin emphasised that 2025 is a pivotal year for Xeros, with a strong focus on globalisation and commercial execution. He expressed confidence that the company is on track to fulfill its potential as a leader in sustainable fabric care.

For more exclusive interviews, subscribe to Proactive’s YouTube channel. Don’t forget to like this video and turn on notifications for updates!

#XerosTechnology #SustainableLaundry #MicroplasticPollution #Innovation #TextileCare #XF3Filter #LaundryTech #ClimateAction #CircularEconomy #InvestorUpdates

ANGLE PLC (AIM:AGL, OTCQX:ANPCY) chief executive Andrew Newland talked with Proactive's Stephen Gunnion about groundbreaking new research using its Parsortix system. The study, conducted by the Marchetti lab at the University of New Mexico Comprehensive Cancer Center, uncovered key insights into how cancer spreads.

Newland explained that Parsortix, the only FDA-cleared system for recovering cancer cells for analysis, was used to study circulating tumor cell (CTC) clusters. The research found that B cells influence the movement of cancer clusters, accelerating metastasis. These findings open new avenues for understanding and potentially preventing cancer spread.

The study also suggests that detecting B cell CTC clusters in melanoma patients could help identify those at risk of disease progression. Pharmaceutical companies may explore ways to target these mechanisms to slow or stop metastasis.

Additionally, Newland highlighted a collaboration with Illumina, with ANGLE set to present at an Illumina webinar. This event could drive further adoption of Parsortix for advanced cancer research.

For more interviews and updates, visit Proactive’s YouTube channel. Don’t forget to like, subscribe, and enable notifications for future content.

#ANGLEPLC #CancerResearch #Parsortix #CTCClusters #Metastasis #Biotech #LiquidBiopsy #Illumina #MedicalBreakthrough #FDAApproved

Faron Pharmaceuticals Limited (AIM:FARN) CEO Dr Juho Jalkanen talked with Proactive's Stephen Gunnion about the company's €12 million fundraising through an oversubscribed share placing. Originally set at €10 million, strong investor confidence in Faron’s programs, particularly in bexmarilimab, led to an increase in the raise.

Jalkanen emphasised that this funding comes at a pivotal time for the company. He highlighted the completion of patient enrollment in the Phase II BEXMAB trial for relapsed refractory myelodysplastic syndromes (MDS), a form of leukemia with a poor prognosis. The Phase II readout, expected in April, will be a major milestone, with early data showing an increase in survival from 5-6 months to 13.4 months and an 80% response rate.

Beyond the readout, Jalkanen outlined key 2025 milestones, including presentations at major medical conferences, discussions with the FDA, and further business developments. He stated, “We are well funded beyond this, and we are geared for success.”

For more insights into Faron Pharmaceuticals' progress, watch the full interview. Don't forget to like, subscribe, and turn on notifications for Proactive's latest updates.

#FaronPharmaceuticals #Bexmarilimab #CancerResearch #BiotechInvesting #PharmaNews #ClinicalTrials #BiotechStocks #FDA #Investing #Healthcare

atai Life Sciences (NASDAQ:ATAI, ETR:9VC) CEO and co-founder Dr Srinivas Rao talked with Proactive's Stephen Gunnion about the promising results in strategic investee Beckley Psytech’s Phase 2a study of BPL-003 for alcohol use disorder.

Rao highlighted the significant unmet need in treating alcohol use disorder (AUD), which affects approximately 400 million people globally and contributes to 3 million deaths per year. The Phase 2a trial, though small with 12 participants, yielded promising results. Patients received a single dose of BPL-003 alongside cognitive behavioral therapy, leading to a 50% abstinence rate over three months. Additionally, heavy drinking days were reduced from 56% to 13%, while abstinent days increased from 33% to 81%.

Looking ahead, atai Life Sciences is anticipating data from a larger Phase 2b study. Rao explained that BPL-003, a 5-MeO-DMT benzoate nasal spray, is being evaluated for its potential to provide long-lasting therapeutic effects with a single administration. This approach contrasts with existing treatments like Esketamine, which require frequent dosing.

Rao emphasized that shorter-duration psychedelic treatments could ease the burden on patients and healthcare providers. By reducing the need for frequent visits, these therapies could make mental health treatment more accessible and scalable.

To stay updated on atai Life Sciences' research, subscribe to Proactive’s YouTube channel, like this video, and enable notifications for future updates.

#ataiLifeSciences #PsychedelicTherapy #MentalHealth #AlcoholUseDisorder #BPL003 #DepressionTreatment #PharmaceuticalResearch #MedicalBreakthrough #InvestorNews #Biotech

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Lindian Resources Ltd (ASX:LIN, OTC:LINIF).

Lindian has awarded the site access road contract for its Kangankunde Rare Earths Project in Malawi to Mota-Engil, a multinational construction firm.

The contract, valued at approximately US$1.3 million, spans an 18-week program and includes roadworks intersecting the M1 highway, 5 kilometres of road construction, civil works around the mining lease access area and a security zone.

This infrastructure development will support the transport of construction materials and equipment, ensuring timely progress on the process plant once funding is secured in Q1 2025.

Built to Malawi Highway Design standards for unsealed gravel roads, the project is expected to improve local connectivity, generate employment and support economic growth.

All necessary government approvals have been obtained, allowing road construction to proceed.

Mota-Engil operates in 21 countries with a global turnover exceeding US$5 billion. The company was selected through a competitive tender process.

Lindian Resources considers this contract a key milestone, signalling its commitment to the Kangankunde Project’s advancement.

The company is finalising commercial agreements, including a fixed-price contract for the process plant and a power supply agreement, as it continues to pursue funding solutions.

#LindianResources, #RareEarths, #MiningProjects, #KangankundeProject, #MiningInvestment, #MalawiMining, #MotaEngil, #InfrastructureDevelopment, #ResourceSector, #MineralExploration, #SiteConstruction, #EconomicDevelopment, #MiningIndustry, #ProcessPlant, #JobCreation, #InvestmentNews, #MiningContracts, #FundingSolutions, #EngineeringProjects, #NaturalResources

Proactive’s Tylah Tully breaks down ‘Just the Facts’ of the latest news from Brookside Energy Ltd.

Brookside is progressing with its strategic expansion in the Anadarko Basin, Oklahoma, with drilling preparations for the Bruins Well in the SWISH Play acreage unmderway.

The Bruins Well, which is expected to spud by the end of this month, will be the first of three planned wells in the company’s 2025 drilling program and will feature a 10,000-foot lateral well targeting the Woodford Shale formation.

Pre-spud activities, including site selection, regulatory approvals and surface agreements, have been completed, and an all-weather drilling pad is under construction.

Brookside anticipates increasing its working interest in the Bruins Well to approximately 70%, subject to final regulatory approvals.

As of December 31, 2024, SWISH Play wells had produced a total of 2.5 million barrels of oil equivalent (BOE).

The Bruins Well is projected to produce more than 1 million BOE in its lifetime, with approximately 640,000 BOE (~53% liquids) expected in the first five years. Estimated gross capital expenditure for the well is around US$11 million.

Brookside views the Bruins Well as a key milestone in its drilling program and aims to maximise production outcomes, create value for shareholders and further expand its operations in the Anadarko Basin.

#BrooksideEnergy, #OilAndGas, #EnergyInvestment, #AnadarkoBasin, #SWISHPlay, #BruinsWell, #DrillingOperations, #USOil, #ShaleProduction, #EnergySector, #Hydrocarbons, #OilExploration, #ResourceDevelopment, #EnergyGrowth, #WellSpudding, #WoodfordShale, #BOEProduction, #OperationalMilestone, #OilIndustry, #ShareholderValue

Cyprium Metals Ltd (ASX:CYM, OTC:CYPMF) executive chair Matt Fifield talked with Proactive’s Tylah Tully about a resource update at the Maroochydore Project and its divestment of the Meekatharra Project to Solstice Minerals Ltd (ASX: SLS).

Fifield highlighted that Maroochydore, which is 80 kilometres from the company's Nifty Copper Complex in WA’s Paterson Province, now contains a substantial 371 million tonnes at 0.43% copper, with a cobalt credit.

He explained that Cyprium had reassessed the deposit with a sulphide-focused approach, leading to a clearer picture of its economic potential.

At a higher cut-off grade, the project holds approximately 100 million tonnes at just under 0.7% copper, representing a strong potential mine opportunity.

The company is now considering ways to integrate Maroochydore with Nifty's infrastructure, including ore sorting, leaching and other processing concepts.

While further work is required, Fifield expressed confidence in the project's long-term value.

Additionally, Cyprium Metals announced the divestment of the Meekatharra Project to Solstice Minerals Ltd, a deal involving cash and shares.

The move aligns with its strategy to focus on core assets in the Paterson region, enhancing shareholder value.

Looking ahead, Fifield pointed to ongoing technical work, a strategic alliance with McMahon, and financial updates as key areas to watch in 2025.

#CypriumMetals #CopperMining #Maroochydore #MiningStocks #Cobalt #PatersonRegion #NiftyCopper #Meekatharra #SolsticeMinerals #Investing #MiningNews #ProactiveInvestors