Clene Inc CEO Rob Etherington joined Steve Darling from Proactive to share news regarding the latest findings from the long-term open-label extension (LTE) of the VISIONARY-MS trial. This trial focuses on participants with stable relapsing multiple sclerosis (MS) and represents nearly three years of follow-up research.

Following the conclusion of the double-blind period of the trial, participants were given the opportunity to continue with CNM-Au8® treatment at a dose of 30mg for an additional 96 weeks during the LTE phase. The analysis encompassed the modified intent-to-treat population, which included all study participants with valid clinical data.

Etherington highlighted the key finding that long-term CNM-Au8 treatment showcased improvements in vision, as measured by low contrast visual acuity, an essential assessment of visual function in individuals living with multiple sclerosis. Remarkably, these improvements in vision persisted for 35 months from randomization, demonstrating the sustained efficacy of CNM-Au8 over an extended period.

Moreover, the data revealed consistent and robust overall enhancements not only in vision but also in cognition among participants treated with CNM-Au8 for nearly three years from randomization. These results are particularly noteworthy for their potential to positively impact disease progression and potentially reverse established disability, representing a significant therapeutic breakthrough for patients with MS.

Full clinical results from the long-term open-label extension will be officially presented at the ninth annual Americas Committee for Treatment and Research in Multiple Sclerosis Forum, scheduled to take place from February 29 to March 2, 2024, in West Palm Beach, Florida.

Clene's commitment to advancing treatments for multiple sclerosis is evident in these promising results, and their ongoing research holds great promise for enhancing the quality of life for individuals affected by this condition. The potential to offer effective long-term solutions and improve both vision and cognitive function is a significant step forward in the battle against multiple sclerosis.

#proactiveinvestors #cleneinc #nasdaq #clnn # #NeurodegenerativeTreatment #ClinicalTrials #MedicalInnovation #ALSResearch #MSAwareness #HealthTech #Biopharmaceutical #InnovationInMedicine #Neuroscience #MedicalBreakthrough #CMAbTherapy #VisionImprovement #CognitiveEnhancement #FDAApproval #MedicalScience #NeurologicalHealth #FutureOfMedicine #MSCommunity #ALSCommunity #MitochondrialHealth #BiotechNews #HealthcareInnovation #RobEtheringtonInterview #MedicalResearchUpdate

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Jane Edmondson, the Head of Thematic Strategy at VettaFi, recently shared essential details about the NATO Future of Defense ETF in a conversation with Steve Darling from Proactive. This ETF is designed to provide investors with exposure to NATO and its allied defense spending, with a particular focus on defense, defense technology, and cyber defense.

What sets this ETF apart is its strict criteria for inclusion. It targets companies that generate at least 60% of their revenue from defense manufacturing, military equipment, and cybersecurity operations, ensuring a diversified portfolio of companies deeply entrenched in the defense sector. Additionally, the ETF's approach allows for a maximum country weight of 60%, which means that non-US defense companies can also participate, contributing to global diversification.

The current geopolitical landscape, notably the Russia-Ukraine conflict, has led to an increase in defense spending, especially in Europe. The addition of new NATO members, such as Finland, and potential future additions like Sweden, has further boosted defense budgets. This geopolitical context has made defense investments an attractive proposition.

Edmondson also highlighted the importance of the ESG (Environmental, Social, and Governance) component in the ETF's strategy. VettaFi has adopted a balanced approach that aligns with UN Global Compact (UN GC) and OECD guidelines. This means that while the ETF focuses on traditional defense, it also incorporates emerging technologies such as AI and cybersecurity. This forward-thinking approach positions the ETF well in the evolving defense sector, where innovation and technology play an increasingly critical role.

As global tensions continue to rise, the investment outlook for companies in the defense sector appears robust. The NATO Future of Defense ETF offers a nuanced perspective that considers not only the dynamics of defense but also the evolving ESG landscape. This approach reflects the intersection of defense and ESG considerations, making it an intriguing option for investors looking to navigate the complexities of today's world while aligning their investments with responsible and sustainable practices.

#proactiveinvestors #hanetf #DefenseETF #NATO #InvestmentOpportunities #GlobalSecurity #ESGInvesting #MilitaryTechnology #CyberDefense #Geopolitics #FutureOfDefense #JaneEdmondson #VettaFi #Verify #StockMarket #SecurityTrends #EUDefense #AIinDefense #UNGC #OECDGuidelines #FinancialNews #MarketInsights #StrategicInvesting #EuropeanSecurity #TechInnovation #Aerospace #MilitarySpending #WorldAffairs

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Troilus Gold CEO Justin Reid joined Steve Darling from Proactive to shed light on the company's ambitions for 2024, following a highly productive 2023. Troilus Gold has been making significant strides, particularly in the expansion and exploration of the Troilus Project, with a particular focus on Zone X22. These efforts have yielded impressive results, including substantial growth in Mineral Resources.

One of the standout achievements in 2023 was a remarkable 126% increase in ounces and a 127% increase in tonnes in the Troilus Project's Mineral Resource, a testament to the company's dedication to efficient resource management. Notably, a significant portion of the Inferred Resources from the 2020 estimate has transitioned into the Indicated category, underscoring the project's maturation and development.

Troilus Gold also made notable progress on the regulatory front, successfully advancing Federal and Provincial permitting, which is a critical aspect of advancing mining projects.

As 2024 unfolds, Troilus Gold is set to continue its rapid pace of growth and development. The company is poised to complete a Feasibility Study in the first quarter of the year, which will include an inaugural Mineral Reserve estimate. This marks a significant milestone in project development, bringing Troilus Gold one step closer to production.

Furthermore, Troilus Gold plans to conduct 25,000 meters of drilling during the year. This drilling will encompass both expansion and definition drilling at select targets along the main mineral corridor, further enhancing the understanding of the project's potential.

The company's commitment to exploration remains unwavering, with continued targeted drilling activities planned at prospective regional targets. These efforts will contribute to Troilus Gold's ongoing mission to uncover additional mineral resources and unlock the full potential of their mining operations.

In summary, 2024 promises to be another busy and productive year for Troilus Gold. With the completion of the Feasibility Study, continued drilling programs, and ongoing exploration activities, the company is well-positioned to maintain its growth trajectory and solidify its status as a significant player in the mining industry.

#proactiveinvestors #troilusgoldcorp #tsx #tlg #otcqx #chxmf #mining #gold

#MiningNews #GoldInvesting #CEOInterview #FeasibilityStudy #ResourceDiscovery #MiningIndustry #InvestmentOpportunity #2024Plans #ExplorationUpdate #QuebecMining #GoldExploration #OreBodyExpansion #MiningAchievements #InvestorInsights #MineralResources #MiningProjects #HighGradeOre #EconomicImpact #InvestmentOutlook #RegulatoryProgress #MiningInnovation #DrillingProgram #MiningFuture #MineralExploration#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Airship AI President Paul Allen joined Steve Darling from Proactive to share news regarding the company's recent accomplishments. Airship Industries has embarked on the delivery of multiple firm fixed-price contracts valued at over $10 million. These contracts have been secured in collaboration with the Department of Homeland Security, and they aim to provide advanced integrated solutions to support real-time intelligence collection operations along the United States' borders. Central to these contracts is the utilization of Airship Industries' cutting-edge edge IoT appliance, Outpost AI.

Outpost AI is a transformative technology that plays a pivotal role in these contracts. It serves as a highly efficient edge analytic processing and secure data transmission system, encapsulated within a compact edge compute device designed to withstand even the most rugged operational environments. Outpost AI leverages an on-board deep learning accelerator, allowing it to process substantial volumes of data at the edge, in real-time. This enables the extraction of actionable intelligence through a range of hot-swappable, custom-trained inference engines.

The applications of Outpost AI are diverse and comprehensive. In the context of the contracts with the Department of Homeland Security, Outpost AI solutions will be instrumental in facilitating real-time intelligence collection operations along the United States' borders. They offer local high-definition recording capabilities along with customizable low-bit-rate video stream encoding. Furthermore, Outpost AI is equipped with on-board edge analytic capabilities, enabling advanced object detection and recognition.

Airship Industries' successful procurement of these contracts underscores their commitment to innovation in the realm of real-time intelligence gathering and border security. The incorporation of Outpost AI technology positions the company as a pioneer in the field, offering highly effective and efficient solutions that enhance the security and surveillance capabilities along the nation's borders.

In summary, Airship Industries' recent achievements in securing these substantial contracts and the deployment of their cutting-edge technology, Outpost AI, highlight their dedication to providing advanced solutions that contribute significantly to border security and intelligence operations. The combination of innovation, efficiency, and adaptability positions Airship Industries as a key player in the field of real-time data analytics and border protection.

#proactiveinvestors #airshipaiholdings #nasdaq #aisp #ai

#AItechnology #SecurityInnovation #DataManagement #VideoAnalytics #LawEnforcementTech #NationalSecurity #EdgeComputing #5GAdvancements #NvidiaTech #TechInnovation #SurveillanceSolutions #SmartSecurity #BorderProtection #RealTimeMonitoring #IntelligentSensors #PublicSafety #MilitaryTech #GreenBeretLeadership #ContractAnnouncement #2024TechTrends #CEOInterview #Fortune500Clients #GovernmentContracts #InnovativeAI#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Manganese X Energy Corp CEO Martin Kepman joined Steve Darling from Proactive to share news The company has entered into a Memorandum of Understanding (MOU) with C4V, a prominent US battery technology leader, which holds immense promise for a potential offtake agreement from Manganese X Energy Corp's Battery Hill High Purity Manganese project located in Woodstock, New Brunswick, Canada.

C4V, renowned for its leadership in renewable battery technology and its involvement in major Gigafactory developments worldwide, including those in Geelong, Australia, and the United States, has shown keen interest in the collaboration. This non-binding agreement is predicated on the possible supply of Electric Vehicle (EV) compliant High Purity Manganese Sulfate Monohydrate, a sample of which is currently undergoing pre-qualification by C4V for use in their Gigafactory joint ventures.

The sample in question was produced as part of Manganese X Energy Corp's Pilot Plant Project, which employs their patent-pending, groundbreaking manganese purification technology. This technology enables the transformation of Battery Hill manganese carbonate into Electric Vehicle compliant High Purity Manganese Sulfate Monohydrate (HPMSM), serving as a precursor to the cathode in battery manufacturing.

This strategic partnership holds the promise of playing a pivotal role in the supply chain for EV batteries, as high-purity manganese is a crucial component in the production of advanced batteries. The MOU represents a significant step forward in the company's quest to contribute to the growing electric vehicle industry while further solidifying its position as a key player in the renewable energy sector.

The collaboration between Manganese X Energy Corp and C4V exemplifies their shared commitment to sustainable energy solutions and highlights the importance of securing a stable supply of critical materials for the EV revolution. As the pre-qualification process advances and the partnership takes shape, both companies are poised to make a lasting impact on the clean energy landscape by fostering innovation and the development of cutting-edge battery technology.

#proactiveinvestors #manganesexenergycorp #tsxv #mn #otcqb #mnxxf

#EVRevolution #BatteryTechnology #RenewableEnergy #MiningInnovation #CleanTech #SustainableMaterials #NorthAmericanMining #GreenEnergy #ElectricVehicles #ManganeseSulfate #TechnologyBreakthroughs #CB4Partnership #EnergyTransition #EcoInnovation #MiningIndustry #CarbonateDeposits #CathodeMaterials #FutureOfTransportation #ZeroEmissions #TechInnovation #SupplyChainSolutions #EcoFriendlyMining #StrategicPartnerships #SustainableDevelopment#invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

C3 Metals Inc (TSX-V:CCCM, OTC:CARCF) CEO Dan Symons speaks to Thomas Warner from Proactive after the Americas-focused copper-gold explorer provided an update on its 2023 exploration results and the strategy for 2024 at its 100%-owned copper-gold projects in Jamaica.

Last year, C3 Metals raised $5 million to advance its 20,000-hectare project in Jamaica, where they identified significant prospects. The company initiated a drilling program, leading to positive results and a near doubling of its market cap. Following this success, they upsized a fundraising round from $7 million to $8 million, positioning them strongly for the current year.

For 2024, C3 Metals is focusing on its Bellas Gate project in Jamaica, planning an extensive 20,000-meter drilling program. This effort is concentrated on a 4-kilometer area rich in exploration indicators like copper and selenium soil anomalies, magnetic highs, and IP chargeability highs. These criteria have consistently yielded strong drilling results for the company.

Despite these advancements, C3 Metals experienced a temporary decline in share price following a share consolidation and fundraising in December. Symons attributed this to delays in exchange approvals and miscommunication among Canadian brokerage firms. He remains optimistic, viewing the current situation as an opportune moment for investors, with the company well-funded and ready to generate significant news flow through its robust drilling program.

#C3MetalsInc #MiningIndustry #JamaicaMining #DrillingProgram #ResourceExploration #MiningInvestment #CopperMining #Geology #MineralExploration #ResourceSector #CEOInterview #MiningNews #InvestmentOpportunities #MiningTechnology #CommodityMarket #ExplorationStrategy #MiningStocks #MetalsAndMining #ResourceDevelopment #MiningSectorUpdate #ProactiveInvestors #copper #gold #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Rainbow Rare Earths Ltd (LSE:RBW, OTC:RBWRF) CEO George Bennett speaks to Thomas Warner from Proactive after the magnet rare earth metals company published an update on its pilot plant operations in South Africa and Florida.

Bennett highlights key achievements, including the success of pilot plant operations in South Africa, producing a superior carbonate mixture by removing cerium, which enhances the feed for the back-end processing in Florida. This progress has enabled continuous process operations in Florida for final separation.

Bennett says that five batches have already been shipped to Florida, facilitating continuous pilot plant operations. The results so far align with expectations, setting the stage for receiving final separated oxides soon. Despite minor delays due to transitioning from sulphate to carbonate and mechanical issues at K-Tech, Bennett remains positive, with the project back on track for this quarter.

Looking ahead, Bennett anticipates further encouraging news and says that his hopes for 2024 include completing their definitive feasibility study, making significant progress in their Brazil project with Mosaic, and securing financing for their South African operations.

#RainbowRareEarths #GeorgeBennett #MiningIndustry #RareEarthElements #PilotPlantOperations #SouthAfricaMining #USGovernmentFinancing #RareEarthProcessing #FloridaOperations #CarbonateProduction #SeparationTechnology #MiningInnovation #EconomicAssessment #BrazilMiningProjects #MiningFinance #2024MiningTrends #ProactiveInvestors #MiningUpdates #CEOInterview #MiningSectorNews #ProactiveInvestors #rareearths #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Light Science Technologies Holdings PLC (AIM:LST) (LSTH) CEO Simon Deacon speaks to Thomas Warner from Proactive after the technology company released a trading update for the 12 months ended 30 November 2023.

Deacon gives the highlights from the year, noting a 13% increase in revenue and a 27% improvement in margin, rising from 17.7% to over 23%. This financial improvement was further exemplified by a substantial reduction in overheads by over 20%, leading to a 50% decrease in expected losses, down to £1.3 million from £2.7 million.

A key development in the past year was the acquisition into LSTH's Controlled Environment Agriculture division of UK-based Tomtech (UK) Limited for £500,000. Tomtech designs, manufactures and installs monitoring and control systems for commercial greenhouses and polytunnels and has been in operation for over 35 years.

Looking ahead, Deacon anticipates continued growth, especially in the controlled environment agriculture sector, fueled by the acquisition of Tomtech, a company with over 35 years of experience.

This sector is expected to be a major growth driver in response to food security concerns and changing weather patterns. The company is preparing for increased market demand, with a pipeline and a forward order book of over £60 million.

#LightScienceTechnologies #SimonDeacon #BusinessGrowth #RevenueIncrease #CompanyStrategy #PassiveFireProtection #ControlledEnvironmentAgriculture #TechAcquisitions #BusinessOptimism #FinancialImprovement #CleanTech #IndustryInnovation #FoodSecurity #ClimateResilience #BusinessInterview #CorporateInsights #CEOInterview #TechnologyExpansion #MarketGrowth #BusinessOutlook2024 #ProactiveInvestors #LightScience #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews

Seeing Machines Ltd (AIM:SEE, OTC:SEEMF) CEO Paul McGlone speaks to Thomas Warner from Proactive about the advanced computer vision technology company's prospects for 2024.

McGlone talks about Seeing Machines' attendance at CES 2024 currently taking place in Las Vegas, highlighting the relevance of the company's automotive tech and AI solutions, which monitor driver behaviour like fatigue and distraction.

McGlone discusses the launch of their third-generation aftermarket product, Guardian Generation 3, at CES. This product, targeting trucks and commercial vehicles, aligns with the upcoming European General Safety Regulation, mandating such technologies in all vehicles from July 2024. This new product, compact and integrating camera and processing, connects to their 24/7 Guardian Centre and offers a long-term technical roadmap, already attracting early adopters.

He goes on to say that Seeing Machines, which was initially focused on mining and heavy vehicles, has expanded into the automotive and aviation sectors. The new European market, driven by regulations, differs from traditional fleet sales, targeting manufacturers for pre-installation in new vehicles. This approach opens up a potential market of 330,000 new commercial vehicles annually in Europe.

For 2024, Seeing Machines aims for steady, high double-digit growth and margin expansion across its segments, moving towards cash breakeven and profitability in the next financial year. This growth is underpinned by increasing royalty flows, monthly recurring revenue from aftermarket connections, and advancements in the aviation sector.

#SeeingMachines #PaulMcGlone #CES2024 #AutomotiveAI #TechInnovation #DriverMonitoring #AItechnology #VehicleSafety #GuardianGeneration3 #CommercialVehicles #EuropeanRegulations #SafetyTech #AutomotiveIndustry #AIIntegration #FleetManagement #AviationTechnology #SustainableTransport #ProfitableInnovation #TechInterview #ProactivInterview

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Incanthera PLC (AQSE:INC) Chairman Tim McCarthy visits the Proactive London Studio to speak with Thomas Warner after the UK-based, dermatology and oncology therapeutics company announced what he calls a "transformational" deal with Marionnaud, a subsidiary of the world's largest health and beauty retailer A.S. Watson.

McCarthy explains the significance of the deal for Incanthera and its shareholders, after a relatively quiet period for the business. The agreement focuses on the rollout of Incanthera's innovative skincare products, starting in Europe.

The products, developed using Incanthera's proprietary technology, efficiently deliver bioactive vitamin B3 through the skin, a feat previously unachievable. This breakthrough has significant implications for skincare, particularly in protecting and repairing skin from UV damage. The initial launch will occur in Switzerland and Austria, with plans for rapid expansion across Europe and Asia, tapping into Watson's vast network of over 16,000 stores.

McCarthy highlights the strategic partnership with contract manufacturer Richland to handle production, ensuring Incanthera can meet the demand without heavy capital investment. This approach aligns with their low-overhead, high-efficiency business model.

McCarthy expects the deal to transform Incanthera from a non-revenue generating entity into a profitable and cash-generative business in 2024. He adds that Incanthera is also exploring expansion opportunities in North America and Australia.

#IncantheraPLC #TimMcCarthy #HealthcareInnovation #BiotechIndustry #SkincareTechnology #UVProtection #VitaminB3 #SkinCareScience #TransformationalDeal #ASWatson #EuropeanMarket #BeautyRetail #CosmeticsScience #PharmaceuticalBreakthrough #InvestorUpdate #StockMarketNews #BusinessInterview #MarketExpansion #CosmeticAdvancements #HealthAndBeauty #2024BusinessTrends #ProactiveInvestors #invest #investing #investment #investor #stockmarket #stocks #stock #stockmarketnews