Un nuovo studio australiano rileva che la mirtazapina, un comune antidepressivo, riduce modestamente il consumo di metanfetamina. Questo apre la strada a un approccio farmacologico integrato che può supportare e potenziare l'efficacia della psicoterapia cognitivo-comportamentale.
Argomenti:
Psicofarmacologia, CBT, Dipendenze, Metanfetamina, HarmReduction, Mirtazapina, RicercaClinica
🌐 Fonte principale:
Lintzeris, N., Monds, L. A., Rivas, C., et al. (2024). Mirtazapine for Methamphetamine Use Disorder: A Double-blind, Placebo-Controlled Randomized Clinical Trial. "JAMA Psychiatry". Published online May 08, 2024. doi:10.1001/jamapsychiatry.2024.0857
https://www.psypost.org/a-common-antidepressant-shows-promise-in-treating-methamphetamine-dependence/
📚 Bibliografia:
📖 Degenhardt, L., Charlson, F., Stanaway, J., Larney, S., Tran, A. D.,... & Vos, T. (2019). The global burden of disease attributable to illicit drug use and mental disorders: findings from the Global Burden of Disease Study 2017. The Lancet Psychiatry, 6(12), 951-970. [Corrisponde al DOI 10.1016/S0140-6736(19)32230-5]
📖 Lintzeris, N., Monds, L. A., Rivas, C., et al. (2024). Mirtazapine for Methamphetamine Use Disorder: A Double-blind, Placebo-Controlled Randomized Clinical Trial. JAMA Psychiatry. Published online May 08, 2024. doi:10.1001/jamapsychiatry.2024.0857
📖 American Society of Addiction Medicine. (n.d.). ASAM Clinical Guideline on the Management of Stimulant Use Disorders. [Riferimento da www.asam.org]
📖 Quinn, B., Stoové, M., Papanastasiou, C., & Dietze, P. (2017). A prospective cohort of people who inject drugs in Melbourne, Australia: The ‘Melbourne Injecting Drug User Cohort Study’(MIX). Drug and alcohol dependence, 171, 143-148. doi:10.1016/j.drugalcdep.2016.10.001
📖 Minozzi, S., Saulle, R., & De Crescenzo, F. (2021). Psychosocial interventions for psychostimulant misuse. Cochrane Database of Systematic Reviews, (5). doi:10.1002/14651858.CD011866.pub3
📖 Brecht, M. L., & Herbeck, D. M. (2013). Methamphetamine use and violent behavior: a systematic review of the literature. Journal of psychoactive drugs, 45(3), 228-238. [Potenziale riferimento associato al tema della ricaduta]
📖 El-Guebaly, N., Carra, G., & Shokraneh, F. (2023). Off-label pharmacotherapies for stimulant use disorder: a systematic review and meta-analysis. New England Journal of Medicine Evidence, 2(10). doi:10.1056/EVIDra2300160
📖 Tapp, A., Zaaijer, S., Oldenhof, J., van den Brink, W., & Schoevers, R. A. (2022). Efficacy and tolerability of pharmacotherapeutic interventions for methamphetamine use disorder: A systematic review and meta-analysis of randomised controlled trials. Drug and Alcohol Dependence, 233, 109295. doi:10.1016/j.drugalcdep.2022.109295
📖 Coffin, P. O., Santos, G. M., Das, M.,... & Vittinghoff, E. (2020). Mirtazapine for methamphetamine use disorder among cisgender men and transgender women who have sex with men: a randomized, double-blind, placebo-controlled phase 2 trial. JAMA psychiatry, 77(3), 246-255. doi:10.1001/jamapsychiatry.2019.3655
📖 Colfax, G. N., Santos, G. M., Das, M.,... & Vittinghoff, E. (2011). Mirtazapine to reduce methamphetamine use: a randomized controlled trial. Archives of general psychiatry, 68(11), 1168-1175. doi:10.1001/archgenpsychiatry.2011.124
📖 Lintzeris, N., Monds, L. A., Rivas, C.,... & Degenhardt, L. (2024). A randomised, double-blind, placebo-controlled trial of mirtazapine for the treatment of methamphetamine (ice) dependence (the TINA trial): study protocol. Trials, 25(1), 238. doi:10.1186/s13063-024-08238-y
----
A cura del dott. Carmine D'Anzica, Psicologo e Psicoterapeuta