La malattia di Alzheimer inizia decenni prima dei sintomi, nel Locus Coeruleus. Una nuova frontiera di ricerca esplora come la stimolazione del nervo vago (VNS) possa proteggere questa area critica, offrendo una speranza per rallentare il declino cognitivo.
Argomenti:
NeuroscienzeCliniche, Alzheimer, StimolazioneNervoVago, LocusCoeruleus, DeclinoCognitivo, Psicoterapia, Neuromodulazione
🌐 Fonte principale:
Mather, M. (2024, June 13). "Vagus nerve stimulation shows promise as a way to counter Alzheimer’s disease and age-related memory loss". The Conversation. Retrieved from https://theconversation.com/vagus-nerve-stimulation-shows-promise-as-a-way-to-counter-alzheimers-disease-and-age-related-memory-loss-269465
https://www.psypost.org/how-stimulating-the-vagus-nerve-could-protect-the-brain-from-alzheimers-disease/
📚 Bibliografia:
📖 Braak, H., & Del Tredici, K. (2011). The pathological process underlying Alzheimer’s disease in individuals under thirty. "Acta Neuropathologica", 121(2), 171-181. https://doi.org/10.1097/NEN.0b013e318232a379
📖 Chandler, D. J. (2020). Locus coeruleus: a new look at the blue spot. "Nature Reviews Neuroscience", 21(11), 606–623. https://doi.org/10.1038/s41583-020-0360-9
📖 Hacker, M. D., Simon, M. M., Kinder, C., Tung, I., Pinto, M., Nia, A., ... & Badran, B. W. (2022). Transcutaneous auricular vagus nerve stimulation in mild cognitive impairment and dementia: A pilot study. "Brain Stimulation", 15(6), 1317-1319. http://doi.org/10.1016/j.brs.2022.09.003
📖 Weigand, A. J., & Bondi, M. W. (2012). An update on the hypothetical model of dynamic biomarkers of Alzheimer's disease. "Current Opinion in Neurology", 25(4), 414-420. https://doi.org/10.1097/WCO.0b013e32835a3432
📖 Sclocco, R., Garcia, R. G., Kettner, N. W., Fisher, H. P., Isenburg, K., Makarova, M., ... & Napadow, V. (2019). The influence of respiration on brainstem and cardiovagal response to pain. "Pain", 160(10), 2346-2360. (Riferimento implicito sulla connessione vago-tronco encefalico)
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A cura del dott. Carmine D'Anzica, Psicologo e Psicoterapeuta