🫁 Pulmonary Embolism in 2026 — A Precision Framework

The new AHA/ACC Acute Pulmonary Embolism Guideline redefines how we classify and treat PE.

Key updates:

• Category A–E clinical classification integrating hemodynamics, biomarkers, and RV imaging

• Age-adjusted D-dimer and YEARS algorithm to reduce unnecessary imaging

• CT pulmonary angiography as preferred diagnostic modality

• RV/LV ratio reporting for objective risk stratification

• LMWH → DOAC preferred for anticoagulation

• Advanced therapies for cardiopulmonary failure

• Mandatory 1-year follow-up to screen for CTEPD

The message is clear: Stratify early. Treat precisely. Monitor longitudinally.