The Charlie Shrem Show

Real-World Assets and Institutional Crypto: The Next Evolution of DeFi with Joe Flanagan Maple Finance


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In this episode, I sit down with Joe Flanagan, the Co-Founder and Executive Chairman of Maple Finance, a leading institutional lending platform in DeFi. With nearly $6 billion in loans issued, Maple is one of the few crypto companies bridging the gap between traditional finance (TradFi) and decentralized finance (DeFi).

We cover some of the biggest trends in crypto right now:

  • The real value of tokenized assets and why tokenization alone isn’t enough
  • How Maple built a transparent, institutional-grade lending market on-chain
  • Why crypto’s next big users won’t come from TradFi—but from meme coin traders evolving into DeFi investors
  • How regulations are shifting in 2025 and what it means for institutional adoption
  • Why DeFi UX is still broken—and how cross-chain strategies can fix it

If you're interested in real-world adoption, institutional DeFi, and where crypto finance is actually headed, this is an episode packed with insights from one of the builders making it happen.

Key Takeaways:

Tokenization alone isn’t the game-changer—what matters is the new financial products that emerge from it.
Institutional-grade DeFi lending is here, but it’s still mostly crypto-native capital participating.
The next wave of DeFi adoption might come from meme coin traders learning how to deploy capital more effectively.
With regulatory uncertainty easing, crypto builders finally have the freedom to innovate at full speed.
Cross-chain user experience is still fragmented, but new infrastructure is emerging to unify ecosystems.

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Thank you for listening to The Charlie Shrem Show. For more free content and access to over 400 episodes, visit www.CharlieShrem.com.

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