ResearchPod

Cardiovascular disease is the world’s leading cause of death. Despite significant advances in its diagnosis, robust treatment remains elusive.

US-based cardiovascular specialists Dr Bradley Bale and Dr Amy Doneen have developed a simple, holistic, and effective method to cure cardiovascular disease. The BaleDoneen Method® targets one of its biggest contributing factors: oxidative stress.

Read their Research Features article: doi.org/10.26904/RF-148-4831388762

Find out more on their website: baledoneen.com

Breast cancer is the most commonly diagnosed cancer worldwide, affecting over 2 million women each year. The most important predictor of both recurrence and survival in patients with breast cancer is if cancer has spread to the axillary lymph nodes.

Dr. Alyssa Cubbison at The Ohio State University Wexner Medical Center specialises in breast imaging.  She puts forward an algorithm she helped create that uses preoperative ultrasound imaging of the axilla when facing suspected breast cancer.  

Read the original research: 10.1016/j.clinimag.2022.04.011

Dr. Cubbison can be contacted via Twitter or email

Every year, millions of people require organ biopsies to check whether the cells are cancerous or not. However, problems can arise when unintended bleeding occurs after taking the biopsy sample and removing the guide needlerequire additional procedures, open surgery, blood transfusions, and longer costs and recovery time. In very serious cases, it can lead to death.  

Single Pass Inc. have developed the first and only disposable electrocautery device that could be extremely useful for preventing bleeding biopsies on solid organs, to quickly, easily and safely cauterize deep tissue through a guide needle to prevent bleeding.  

Read more at singlepass.co

LED lighting provides brighter, lower-power, longer lasting illumination than traditional lighting systems, and can be programmed to change color and brightness instantaneously. Despite this, lighting in smart buildings still consumes a significant amount of energy.

Professor Archan Misra and fellow researchers at Singapore Management University look at the development of a smart lighting control system, CS-Light, designed specifically for open-floor indoor layouts, such as offices, collaborative workspaces and campuses.

Read the original article:  https://doi.org/10.1145/3486611.3486657

Rainer Maria Rilke's poems creatively expressed ideas that are hard to put into words, and his writings on the work of sculptor Auguste Rodin glorified their skill at creating tiny surfaces that reflect light to bring sculptures to life. 

The poet’s apparent hero worship of Rodin’s sculpting talents is of great interest to Dr Nicholas Reynolds, a Lecturer in Modern Languages and Literatures at Trinity University, Texas.  But it was a turbulent relationship that led to a final break in 1913, which echoes one of Rilke’s prose stories that suggests that two masters cannot be in the same room. 

Read the original chapter: https://doi.org/10.1007/978-3-030-74470-0_7

Listen to more about Dr Reynolds work in a previous episode here

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease, the precise cause of which is still unclear. 

Professor Shunichi Shiozawa from Kobe University, Japan, uncovers the underlying cellular and molecular mechanisms of systemic autoimmunity and identifies a novel key player. Shiozawa demonstrates that overstimulation of the host’s immune system by an immunogenic pathogen kickstarts the generation of new T lymphocytes, which induce SLE and could be a future target of SLE cell therapies.

Read more in Research Outreach: doi.org/10.32907/RO-136-4710684972

Read the original research: doi.org/10.1016/j.isci.2021.103537

The Austrian poet and writer, Rainer Maria Rilke, explored many powerful and emotive themes, making one consider life, experience, reality and much more. 

In his monograph on the writings of Rilke, Dr Nicholas Reynolds, from Trinity University in San Antonio, explores the themes of sound and memory, and subsequently posits a theory of how artists tap into their subconscious in their creative process.

Read Dr Reynolds' original research: doi.org/10.1007/978-3-030-74470-0_2 

Researchers are passionate about contributing to the ever-expanding network of knowledge. So, how can scholars ensure that their work is available for future generations to access and build on?  

CLOCKSS is a digital archive for publishers and research libraries. Executive Director, Dr Alicia Wise, suggests that the work of the preservation community is in perpetual motion, and that collaboration between authors, libraries, publishers, and archival services is imperative for passing the knowledge baton to future learners.

Visit their website: CLOCKSS

Cyanovirin-N, or CV-N for short, is a broadly binding molecule to glycopeptides and glycan structures on viral envelope spikes, which allows for screening of these structures by protein-interaction based sensor technologies.

Dr. Irene Maier, Lecturer at the Medical University of Vienna, Austria, examines the molecular understanding of immune diseases. Maier has designed new antiviral CV-N variants and measured their binding constants to glycoproteins exposed at the surface of immune-stimulating cells, which has the potential to revolutionize treatments against viral infections.

Find out more about Irene's work on ResearchGate

Read the original research: https://www.jove.com/de/t/63541/engineering-antiviral-agents-via-surface-plasmon-resonance

Strokes are a leading cause of death and disability worldwide, leaving a pressing need for effective neuroprotective drugs. 

A team of researchers from the University of Copenhagen led by Prof Petrine Wellendorph have developed a promising drug candidate that may offer a chance for improving brain function and working memory among stroke patients. 

Their work is funded by the Novo Nordisk foundation, and details can be seen on the Wellendorph Lab webpage here: https://drug.ku.dk/disciplines/molecular-and-cellular-pharmacology/wellendorph-lab/

Read their original article here: https://journals.sagepub.com/doi/10.1177/0271678X231167920