The current standard of care is to provide a bolus of 30 mL per kg of isotonic fluid for patients with septic shock. Recent retrospective studies question this practice. Join host, Geoff Wall, as he reviewed a NEJM article on the role of fluids in septic shock.

The GameChanger
Large boluses of fluid during septic shock may have unintended adverse events. Some data show that an approach with restrictive fluids may have no difference in death or adverse outcomes.

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Show Segments
00:00 - Introductions
01:38 - Background on Septic Shock and Current Treatment
04:47 - Meyhoff et al Study
15:17 - Gamechanger: Study Findings
22:51 - Connecting to Practice
23:57 - Closing Remarks 

Host
Geoff Wall, PharmD, BCPS, FCCP, CGP
Professor of Pharmacy Practice, Drake University
Internal Medicine/Critical Care, UnityPoint Health

References and Resources

• Restriction of Intravenous Fluid in ICU Patients with Septic Shock

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CE Information

Learning Objectives
Upon successful completion of this knowledge-based activity, participants should be able to:
1. Critique the Meyhoff et al study evaluating restrictive fluids in septic shock
2. Discuss current approaches to fluid resuscitation in patients with septic shock

0.05 CEU/0.5 Hr
UAN: 0107-0000-22-371-H01-P
Initial release date: 10/10/2022
Expiration date: 10/10/2023
Additional CPE and CME details can be found here.

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