Savage discusses the upcoming changes to the US dietary guidelines as proposed by RFK Jr. The new guidelines call for increased consumption of saturated fats, diverging from established recommendations based on scientific studies. The new guidelines are based on research by Dr. Ronald Krauss, who found that saturated fats may be less harmful than previously thought. However, Dr. Krauss himself does not recommend increasing saturated fat intake. The host critiques RFK Jr.'s lack of scientific and medical background and warns against adopting the carnivore diet, which eliminates all plant-based foods. The discussion covers the history of the diet-heart hypothesis, the French paradox, and conflicts of interest in past dietary guidelines.