The Flu Pandemic of 1918 Before COVID-19, the most severe pandemic in recent history was the 1918 influenza virus, often called “the Spanish Flu.” The virus infected roughly 500 million people—one-third of the world’s population—and caused 50 million deaths worldwide (double the number of deaths in World War I). In the United States, a quarter of the population caught the virus, 675,000 died, and life expectancy dropped by 12 years. With no vaccine to protect against the virus, people were urged to isolate, quarantine, practice good personal hygiene, and limit social interaction. https://www.archives.gov/news/topics/flu-pandemic-1918 The Spanish Flu Epidemic – The Worst... View Article