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Summary
In this episode of Irreverent Health, Matt and Tom sit down with Ryan Root, whose life story runs through biochemistry, underground hormone distribution, federal prison, and ultimately redemption through a legitimate hormone optimization practice.
Ryan shares how undiagnosed low testosterone shaped his early life — fatigue, depression, lack of confidence, and being mislabeled as lazy — and how discovering testosterone therapy radically transformed his physical, mental, and social experience. That discovery led him to help others, which quickly turned into a massive black-market hormone operation that was ultimately dismantled in a nationwide sting known as Operation Cyber Juice.
But this conversation is not about crime — it’s about what the medical system still misunderstands about hormones. Ryan explains why testosterone and HRT became stigmatized through a mix of Olympic scandals, war-on-drugs politics, pharmaceutical economics, and gaps in medical education. He also shares how his 20 years of empirical experience working with over 20,000 people now informs his legal company, Hormones For Me.
The discussion explores hormone deficiency as a root cause of obesity, depression, metabolic disorder, and fatigue, the limitations of GLP-1 weight loss drugs when hormones are ignored, and the future of hormone therapy through genetics, bloodwork, and AI-driven protocols.
Takeaways
Chapters
00:00 Introduction & NYC nostalgia
05:10 Why HRT and testosterone are suddenly everywhere
09:00 Growing up with undiagnosed low testosterone
15:30 Discovering testosterone and radical transformation
22:00 Why testosterone became stigmatized
30:00 Helping others → underground demand
35:30 The business explodes nationwide
38:00 The 5 a.m. DEA raid
45:00 Prison, reflection, and redemption
50:00 Launching HormonesForMe.com
58:00 Genetics, AI, and the future of hormone optimization
1:05:00 Obesity, GLP-1s, and metabolic disorder
1:12:00 Where to find Ryan & closing thoughts
The post Ryan Root & Hormone Replacement Therapy first appeared on Irreverent Health.
By Tom Ingegno and Matt Hampton5
33 ratings
Summary
In this episode of Irreverent Health, Matt and Tom sit down with Ryan Root, whose life story runs through biochemistry, underground hormone distribution, federal prison, and ultimately redemption through a legitimate hormone optimization practice.
Ryan shares how undiagnosed low testosterone shaped his early life — fatigue, depression, lack of confidence, and being mislabeled as lazy — and how discovering testosterone therapy radically transformed his physical, mental, and social experience. That discovery led him to help others, which quickly turned into a massive black-market hormone operation that was ultimately dismantled in a nationwide sting known as Operation Cyber Juice.
But this conversation is not about crime — it’s about what the medical system still misunderstands about hormones. Ryan explains why testosterone and HRT became stigmatized through a mix of Olympic scandals, war-on-drugs politics, pharmaceutical economics, and gaps in medical education. He also shares how his 20 years of empirical experience working with over 20,000 people now informs his legal company, Hormones For Me.
The discussion explores hormone deficiency as a root cause of obesity, depression, metabolic disorder, and fatigue, the limitations of GLP-1 weight loss drugs when hormones are ignored, and the future of hormone therapy through genetics, bloodwork, and AI-driven protocols.
Takeaways
Chapters
00:00 Introduction & NYC nostalgia
05:10 Why HRT and testosterone are suddenly everywhere
09:00 Growing up with undiagnosed low testosterone
15:30 Discovering testosterone and radical transformation
22:00 Why testosterone became stigmatized
30:00 Helping others → underground demand
35:30 The business explodes nationwide
38:00 The 5 a.m. DEA raid
45:00 Prison, reflection, and redemption
50:00 Launching HormonesForMe.com
58:00 Genetics, AI, and the future of hormone optimization
1:05:00 Obesity, GLP-1s, and metabolic disorder
1:12:00 Where to find Ryan & closing thoughts
The post Ryan Root & Hormone Replacement Therapy first appeared on Irreverent Health.

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