Chemotherapy, one of the mainstays of cancer treatment, can unfortunately act as a double-edged sword. While achieving the intended aim of killing cancerous cells, it also generates an accumulation of cell debris, which in turn, promotes tumour growth by stimulating inflammation in the tumour microenvironment. Dr Dipak Panigrahy and his colleagues from Harvard Medical School, USA, have conducted several studies in mice showing that targeting the tumour cell debris-mediated surge of proinflammatory and protumourigenic factors provides a strategy for enhancing the efficacy of chemotherapy.

Children and youth who experience trauma often develop posttraumatic stress symptoms, and some go on to develop posttraumatic stress disorder or PTSD. Toria Herd from the Pennsylvania State University, US, is exploring the factors that put adolescents at risk of developing PTSD and also those that may protect against this consequence associated with trauma exposure. Her findings have important implications for the trauma-informed care of young people and the reduction of the long-term impact of trauma on individuals and families.

The multi-theory model (MTM) of health behavior change provides a theoretical framework for understanding and promoting health behaviors. Professor Manoj Sharma from the University of Nevada, Las Vegas, the originator of this model, has applied this model to breast cancer and undertaking mammography screening in women from groups underserved in current healthcare. His findings have important theoretical and practical implications.

Sustainable Development Goal 12 refers to responsible production and consumption. Professor Rafael Ravina-Ripoll at the University of Cádiz in Spain and his colleagues (Luis Bayardo Tobar-Pesantez, Estela Núñez-Barriopedro and David Almorza-Gomar) have addressed a lack of research and understanding in the literature about how management models based on happiness management can help promote sustainable and ethical development in the COVID-19 era.

The UK-based Pregnancy Care Integrating Translational Science, Everywhere (PRECISE) Network has set up biorepositories across sub-Saharan Africa to investigate the causes of placental pregnancy complications and enhance research capacity. The project encountered several challenges relating to facilities, staffing, training, cultural barriers, procurement, shipping and sample storage which impacted project timings and budget. However, with appropriate training and infrastructure development, the researchers have shown that is possible to facilitate high-quality sample collection in this region. This important achievement provides vital encouragement in support of establishing further biorepositories in less affluent regions.

Interventions designed to improve health, including targeted drugs and medical devices, typically undergo a complex and lengthy process of development. In a collaboration between the University of Wisconsin-Madison, Cornell University, the National Institutes of Health and Case Western Reserve University in the USA, experts Dr Clara Pelfrey, Dr Linda Scholl and colleagues have designed a case study protocol to improve understanding of this process.

Discovering new phases of matter and classifying such phases are among the most important goals in physics. In a new study, Dr Tie-Cheng Guo and Professor Li You at Tsinghua University in Beijing present a new methodology to discover new quantum phases of matter, using the concept of ‘time order’. Through identifying and defining quantum phases from this perspective, time order could become a new paradigm in physics, helping researchers to gain more insight into quantum many-body systems.

The inability to access land is a major cause of poverty in agricultural societies. Women, who are less likely to own, rent, buy or inherit land, are particularly affected and access to communal land may provide a vital lifeline. Dr Jozelin María Soto-Alarcón and Dr Diana Xóchitl González-Gómez set out to investigate the use of communal land in a rural community in Mexico, investigating the strategies used by a collective of women to achieve access to this critical resource.

While research into the experiences of people with autism and their families is flourishing, there remains relatively little research on the experiences of typically developing siblings, particularly those on the brink of adulthood. Ms Caitlin Calio, Masters of Teaching, and Professor Ann Higgins-D’Alessandro at Fordham University in the USA, are dedicated to overcoming this important knowledge gap to help inform both theory and the development of appropriate practical support.

Professor Zygmunt Pizlo at the University of California-Irvine has advanced degrees in both engineering and psychology. He is drawing on his extensive experience in these often disparate fields to explore how fundamentals in physics can explain how we see the world around us. His novel work extrapolating from the importance of symmetry in physics and the natural world opens up exciting possibilities for psychology and cognitive science.