SciPod

The UNAIDS estimates that 38 million people currently live with human immunodeficiency virus (HIV) infection. Combination antiretroviral treatment has had great success in saving lives but is also associated with numerous medical and public health challenges. Vaccination remains the best and most cost-effective option for controlling HIV infection across the world. Professor Tomáš Hanke jointly from the University of Oxford, UK, and Kumamoto University, Japan, designs vaccines and coordinates clinical programmes testing the most advanced vaccine candidates developed by his team in the UK, Europe, USA and Africa.

Sweet basil is among the most popular and economically important culinary herbs, but by 2010, US production began to feel the impact of a newly emerging destructive disease: basil downy mildew. At that time, no sweet basil varieties were resistant to basil downy mildew and growers began relying heavily on fungicide application to avoid devastating crop losses. Dr James Simon at Rutgers University had been researching basil for 25 years and was eager to tackle this problem. Eight years later, Dr Simon’s team is proud to have successfully developed 12 new downy mildew resistant varieties of sweet basil and two varieties resistant to fusarium wilt disease.

More than 80% of agricultural land in the US is managed by farmers whose operations fall between small-scale farms with direct access to local markets, and larger industrialised farms. These farmers in the ‘middle’ increasingly struggle to find a place within the larger food production system. Through his work as part of the ‘Agriculture of the Middle’ Initiative, Dr Thomas Gray of the Rural Business-Cooperative Service at the US Department of Agriculture has been studying different types of cooperative structures for best adaptability to socio-economic and food consumption patterns for mid-size farm survival.

Young people can often be discouraged from engaging with STEM subjects because they seem to have little obvious connection to their everyday lives. At Winston-Salem State University in North Carolina, an innovative program led by Dr Tennille D. Presley, is seeking to engage students by combining physics and biology with an art that is central to many students’ social lives: music. Early results from the program suggest that it has been successful in making science exciting and showing students that physics is involved in everything.

Machine learning is rapidly advancing the decision-making capabilities of today’s computers, yet without an in-depth knowledge of the programming it involves, many engineers and researchers find current technology inaccessible. Dr Paul Robertson at Dynamic Object Language Labs (DOLL) in Massachusetts believes that a solution to the issue may have been hidden in plain sight: machine learning itself. His ideas have now culminated in ‘Pamela’: a universal, open-source language capable of modelling real-world systems, and building plans to overcome challenges. The language and its related tools could soon open up significant opportunities in the emerging field of artificial intelligence.

Health advocacy is an often-overlooked part of the work of public health specialists, but in many ways, it can be argued to have the greatest long-term impact on the population’s health. Here we look at the impressive work of Professor Janet Gray (Vassar College) and Public Policy Strategist Ms Nancy Buermeyer, working with colleagues at Breast Cancer Prevention Partners, the leading USA science-based policy and advocacy organisation to focus on preventing breast cancer by eliminating exposure to toxic chemicals and radiation linked to the disease.

When the incomes of wealthy individuals and companies grow faster than the economy itself, income inequality rises in society. However, industrialised economies such as the UK and Germany have experienced sustained declines in growth, and policies to promote economic growth often clash with environmental sustainability. Therefore, economists are attempting to find solutions for decreasing income inequality without the need to stimulate economic growth. In a recent paper, Dr Tilman Hartley at the Autonomous University of Barcelona and his collaborators outline policy interventions that can improve income equality during periods of slow or no growth.

Buddhist-derived meditation is becoming increasingly recognised as being able to promote physical, emotional, and mental health in the Western world. Although an extensive literature supports the many benefits of meditation, the adverse effects remain underreported. The Varieties of Contemplative Experience study was initiated by Dr Willoughby B. Britton at Brown University, Rhode Island, to investigate the potentially darker side of meditation.

Climate change is mostly the result of elevated carbon dioxide emissions. Over the past two decades, research groups have been searching for new technologies that capture carbon dioxide from the atmosphere as an effective way of reversing climate change. Dr Radu Custelcean and his colleagues at the Oak Ridge National Laboratory in the US specialise in this endeavour. The team is developing novel materials and methods that filter carbon dioxide out of the air in an energy-efficient manner.

With a sharp increase in the public use of online shopping in recent years, which has spiked further due to the COVID-19 pandemic, the importance of warehouse positioning to provide an optimal delivery service has become a significant area of focus for retailers. Similarly, bike sharing in major cities has also seen an astronomical rise in usage – prompting questions about how bike stations can be best positioned. Stations in optimised locations would require minimal interference to change the stock levels, while also ensuring the greatest accessibility to users. Dr Xiong and his colleagues at Rutgers University have been using the ubiquity of big data to better optimise these systems for both cost efficiency and standard of service to customers, testing their findings in real-world scenarios.