SciPod

Attached and implanted technologies are now part of everyday life for many millions of people. Yet as the capabilities of these devices have advanced rapidly in recent years, lawmakers have struggled to keep pace. Professor Muireann Quigley at the University of Birmingham believes that it is now more critical than ever that the law catches up with the technological and social change wrought by attached and implanted medical devices, especially ‘smart’ ones. Through the Everyday Cyborgs 2.0 and DIY Diabetes projects, she and her colleagues hope to bring law, regulation, and policy regarding these technologies into the 21st century.

Plants are more tolerant of changes in their chromosome number than animals. Even dramatic changes, such as doubling of the entire genome, sometimes leads to beneficial outcomes. Though a history of genome doubling is common in most plants, the chromosome number in many plants does not reflect this. Complex genome downsizing processes help these plants shed extra genetic information, but are poorly understood. Through comparisons with ferns – a group with high chromosome numbers – Dr Paul Wolf from the University of Alabama in Huntsville aims to shed light on genome downsizing.

Tropical forests are some of the most biodiverse ecosystems on the planet, but extensive deforestation has pushed many species to the brink of extinction. Conservation efforts have been limited by political and socioeconomic backgrounds of each region. By integrating ecological and social research techniques, Dr Peter Beck at St Edward’s University, Dr Michael Wasserman of Indiana University and their colleagues examine the effectiveness of tropical forest conservation strategies and the factors that encourage people to conserve their forests. Their extensive project also provides international research experience to STEM students from underrepresented backgrounds, and helps foster scientific and cultural exchange between countries.

Sound waves are all around us. They govern vibrations from the sweetest of sound to the most destructive earthquakes. Now, a team of researchers across the US has embarked on an ambitious project, named ‘New Frontiers of Sound’, which will pave the way for advanced technologies that operate using sound waves. Combining the expertise of more than 30 leading scientists and engineers from across the field of acoustics, the project promises to discover new properties of sound, while offering exciting opportunities for researchers from a diverse range of backgrounds.

In recent decades, advancements in agricultural practices have made the large-scale production of cheap and nutritious food possible. However, these practices are often damaging to the environment, making them unsustainable in the long term. Technology is now sufficiently developed that many of these environmental impacts can be reduced or mitigated, by using ‘big data’ to inform farming management decisions. Dr Bruno Basso from Michigan State University and his network of researchers have been exploring how digital technologies could usher in a new era of sustainable agriculture that balances competing economic and social interests while minimising trade-offs.

To help feed a global population of the magnitude expected by 2050, fish farming will need to increase dramatically. Two main factors limiting the expansion and future sustainability of the aquaculture industry are finding feed replacements that have equivalent or improved nutritional benefits, and preventing disease. Over the last 20 years, Dr Ken Overturf and his team at the USDA’s Agricultural Research Service in collaboration with the Aquaculture Research Institute at the University of Idaho have been working to establish a genetic enhancement program for rainbow trout, with the aim of helping to boost global fish production in a sustainable manner.

Engineering mechanics can provide medical researchers with invaluable insights into the diverse mechanisms contained within the human body, and the conditions that arise when they go wrong. Over a career spanning four decades, Dr Nigel Shrive at the University of Calgary has offered significant contributions to this field. His research is now helping to improve the lives of many millions of people who are currently suffering from mechanical failure within the body. Elsewhere, his work has also enabled countries to protect their priceless historical heritage.

Humans have a long history of developing crops with improved characteristics, benefitting consumers, and farmers alike. Selective breeding, inducing genetic mutations, and, more recently, gene editing, are all tools that are used to produce plants with beneficial traits. As with any breeding technique, gene editing can lead to unintended genetic changes, but how does the prevalence of these off-target changes compare with those arising from other breeding practices? Plant scientists from the University of Minnesota and collaborating organizations reviewed the rate of unintended changes arising from gene editing with those from other plant development techniques. The researchers conclude that off-target edits in crops present no new safety concerns compared to unintended genetic changes that occur using other breeding techniques.

Individuals with chronic kidney disease commonly also suffer from renal anaemia. Renal anaemia, a condition in which individuals lack enough red blood cells to adequately supply oxygen to the tissue, can have many underlying causes. Treatment is based on hormones that stimulate the production of red blood cells but this has varying outcomes and it is difficult to estimate the effects treatment will have on a specific patient. Dr Doris H. Fuertinger , at Fresenius Medical Care Deutschland is using a mathematical model to predict the causes of renal anaemia and to guide treatment for individual patients.

Big data is now central to the operation of many online companies, but until now, the wealth of information it provides has remained largely untapped by manufacturers. Dr Tim Young at the University of Tennessee believes that through data science, this information could be used to significantly streamline the operations of many manufacturing industries. His work provides the widely varied parties involved in these processes with important new insights into how they should handle their data, ultimately helping them to improve the efficiency of their operations.