What does Jesus mean here when he talks about fruit and fruitfulness in life? When the Bible talks about fruit it is talking about deep positive changes in your life. In some places it also suggests the idea of a deep and positive influence on others for Christ. The best way to see this is to look at another passage, Galatians 5:22-23, which says; But the fruit of the Spirit is love, joy, peace, patience, kindness, goodness, faithfulness, 23 gentleness and self-control. Against such things there is no law. In the vine and the branches Jesus gives us an image to tell us how those kinds of changes can come about in our lives.