Short Wave

How did life start on Earth? The answer is a big scientific mystery scientists are actively investigating. After talking with many scientists, host Regina G. Barber found that an abundance of water on Earth is most likely key, in some way, to the origin of life — specifically, in either deep sea hydrothermal vents or in tide pools. It's for this reason some scientists are also exploring the potential for life in so-called "water worlds" elsewhere in the solar system, like some of the moons of Jupiter and Saturn. This episode, Regina digs into two water-related hypotheses for the origin on life on Earth — and what that might mean for possible alien life.

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For years, we've been asking, "Which came first: the chicken or the egg?" Maybe what we should have been asking is, "Which came first: the frog or the tadpole?" A new paper in the journal Nature details the oldest known tadpole fossil. Ringing in 20 million years earlier than scientists previously had evidence of, this fossil might get us closer to an answer.

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NOTE: This episode contains multiple high-pitched noises (human and other animals) that some listeners might find startling or distressing.

In this episode, host Regina G. Barber and NPR correspondent Nate Rott dive into the science behind the sound of fear. Along the way, they find out what marmot shrieks, baby cries and horror movie soundtracks have in common — and what all of this tells us about ourselves.

If you like this episode, check out our episode on fear and horror movies.

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Humans have seen a significant increase in life expectancy over the past 200 years — but not in overall lifespan. Nobody on record has lived past 122 years. So, for this early Halloween episode, host Regina G. Barber asks: Why do we age and why do we die? Microbiologist Venki Ramakrishnan explains some of the mechanisms inside of our bodies that contribute to our decay — and tells us if it's possible to intervene in the process.

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What's your favorite apple? Maybe it's the crowd-pleasing Honeycrisp, the tart Granny Smith or the infamous Red Delicious. Either way, before that apple made it to your local grocery store or orchard it had to be invented — by a scientist. So today, we're going straight to the source: Talking to an apple breeder. Producer Hannah Chinn reports how apples are selected, bred, grown ... and the discoveries that could change that process. Plus, what's a "spitter"?

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More than a million species are at risk of extinction, many within decades, because of human actions. Among them? The kāhuli, Hawaii's native tree snails that are some of the most endangered animals on the planet. At one point, there used to be about 750 species of snails in Hawaii — almost all of them found nowhere else. Now, they are rapidly disappearing. NPR climate reporters Lauren Sommer and Ryan Kellman join host Emily Kwong to tell the story of the small team caring for the last of some of these snail species — and their fight against extinction.

Read more of Lauren and Ryan's reporting.

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For the past 70 years, schizophrenia treatments all targeted the same chemical: dopamine. While that works for some, it causes brutal side effects for others. An antipsychotic drug approved last month by the FDA changes that. It triggers muscarinic receptors instead of dopamine receptors. The drug is the result of a chance scientific finding ... from a study that wasn't even focused on schizophrenia. Host Emily Kwong and NPR pharmaceutical correspondent Sydney Lupkin dive into where the drug originated, how it works and what it might shift for people with schizophrenia.

Read more of Sydney's reporting.

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Every American red wolf alive right now is descended from only 14 canids. In the 1970s, humans drove the red wolf to the brink of extinction. Because of that, red wolves today have low genetic diversity. But what if we could recover that diversity ... using "ghost genes"?

That's right, today's episode is a ghost story. Along the way, we get into gene dictionaries, the possibilities of poo and how a photo of a common Texas coyote started it all.

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Calling all foragers! The new board game Undergrove, co-designed by Elizabeth Hargrave and Mark Wootton, is all about the symbiotic relationships between trees and fungi. Players assume the role of mature Douglas fir trees and partner with mushrooms, which represent the mycorrhizal network.

P.S. If the name "Elizabeth Hargrave" sounds familiar — she also designed the bird-collecting game Wingspan.

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In the humid rainforests of northern and eastern Madagascar reside seven newly described frog species. They often hang out near fast, flowing rivers. These treefrogs' high-pitched, "futuristic" sounds may help male frogs attract females over the sound of nearby rushing water. They also are what inspired their Star Trek-themed names.

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