In the second episode, hosts Brittany and Laura discuss sexual tension between characters, how one of Brittany's friends tagged along on a first date to sketch her, and an unfortunate incident when Laura drank her brother's urine. Also, a guest segment of "Quinn the Feminist" with Gaby Dunn discussing Quinn's polyamorous ways.

On the first episode of "Sicker Sadder World", hosts Brittany and Laura discuss Helen Morgendorffer's allure, Laura's "Singled Out" style high school assembly and the rollback on protection for transgender students. Also included is a guest segment titled "Quinn the Feminist" with Gaby Dunn, makes us wonder: Is Quinn actually the most feminist of them all?