The Microscopists

Sir Paul Nurse (The Francis Crick Institute)


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#36 – Today's guest on The Microscopists is Nobel Laureate Sir Paul Nurse, Chief Executive and Director of The Francis Crick Institute in London. Paul's early career used microscopic screening to identify temperature-sensitive cell-cycle mutants in fission yeast. This work led to the identification of the cell division cycle 2 gene (cdc2), which encodes a kinase critical for cell cycle progression.
It was for this work that he was awarded the 2001 Nobel Prize in Physiology or Medicine alongside Tim Hunt and Leland Hartwell.
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