The Lucchese crime family is one of the "Five Families" that dominate organized crime activities in New York City, United States, within the nationwide criminal phenomenon known as the American Mafia.

Robert Francis Garrow Jr. was an American serial killer who was active in New York in the early 1970s. Garrow went on an 18-day killing spree and stabbed four people to death before being apprehended. His criminal trial, known as the Buried Bodies Case, became an important case in legal ethics after his attorneys refused to disclose the location of the bodies of two of his victims, citing attorney-client privilege. Garrow was later shot dead while escaping from prison in 1978.

Winnie Ruth Judd, born Winnie Ruth McKinnell, also known as Marian Lane, was a medical secretary in Phoenix, Arizona, who was accused of murdering her friends, Agnes Anne LeRoi and Hedvig Samuelson, in October 1931. The murders were discovered when Judd transported the victims' bodies, one of which had been dismembered, from Phoenix to Los Angeles, California by train in trunks and other luggage, causing the press to name the case the "Trunk Murders". Judd allegedly committed the murders to win over the affections of Jack Halloran, a prominent Phoenix businessman.

Peter Norris Dupas is an Australian convicted serial killer, currently serving three life sentences without parole for murder and primarily for being a serious habitual offender. He has a very significant criminal history involving serious sexual and violent offenses, with his violent criminal history spanning more than three decades, and with every release from prison has been known to commit further crimes against women with increasing levels of violence. His criminal signature is to remove the breasts of his female victims.

Bruce George Peter Lee (born Peter George Dinsdale) is one of Britain's most prolific serial killers. He confessed to a total of 11 acts of arson and was convicted of 26 counts of manslaughter. 11 of these were overturned on appeal. Lee was imprisoned for life in 1981.

Herbert William Mullin is an American serial killer who killed thirteen people in California in the early 1970s. He confessed to the killings, which he claimed prevented earthquakes. In 1973, after a trial to determine whether he was insane or culpable, he was convicted of two murders in the first degree and nine in the second, and sentenced to life imprisonment. As of 2021, he has been denied parole eight times and is unlikely to ever be released.

Robert Charles Browne is an American serial killer convicted of two murders and serving a double-life sentence in the Colorado Territorial Correctional Facility. Browne is also a self-professed serial killer, alleging that he killed 48 people, mostly women, as well as an additional woman in South Korea during his time in the US Military. Though many claims made by Browne remain uncorroborated if accurate his account would make him one of the most prolific serial killers in American history.

Mark Goudeau is an American serial killer, kidnapper, and thief. Goudeau terrorized victims in the Phoenix metro area between August 2005 and June 2006. Coincidentally, Goudeau was active at the same time as two other Phoenix serial killers, jointly known as the "Serial Shooter.”

Rodney James Alcala was an American serial killer and rapist who was sentenced to death in California for five murders committed in that state between 1977 and 1979 and received an additional sentence of 25 years to life after pleading guilty to two homicides committed in New York in 1971 and 1977. Alcala's true number of victims remains unknown and could be much higher.

Elias Abuelazam is an Arab-Israeli convicted murderer and a suspect in racially motivated serial killings and stabbings. He is suspected in a string of eighteen stabbing attacks from May to August 2010 which resulted in five deaths. Most of the alleged attacks occurred in Genesee County, Michigan (particularly in and around Flint). Five stabbings occurred elsewhere: three in Leesburg, Virginia, one in Toledo, Ohio, and one in his native home in Ramla, Israel. All of his alleged victims were described as "small framed" (e.g. short, thin, non-muscular) men, most of them African Americans.