Drs Harrington, Rodriguez, and Ridker discuss the changing field of cardiac prevention, where imaging fits in, and the new concept of standard modifiable risk factor-less patients.

This podcast is intended for healthcare professionals only.

To read a transcript or to comment, visit

https://www.medscape.com/author/bob-harrington

Life's Essential 8: Updating and Enhancing the American Heart Association's Construct of Cardiovascular Health: A Presidential Advisory From the American Heart Association

https://doi.org/10.1161/CIR.0000000000001078

Development and Validation of the American Heart Association's PREVENT Equations

https://doi.org/10.1161/CIRCULATIONAHA.123.067626

C-Reactive Protein and Cardiovascular Risk Among Women With No Standard Modifiable Risk Factors: Evaluating the 'Smurf-Less but Inflamed'

https://doi.org/10.1093/eurheartj/ehaf658

Mortality in STEMI Patients Without Standard Modifiable Risk Factors: A Sex-Disaggregated Analysis of SWEDEHEART Registry Data

https://doi.org/10.1016/S0140-6736(21)00272-5

Inflammation, Cholesterol, Lipoprotein(a), and 30-Year Cardiovascular Outcomes in Women

https://www.nejm.org/doi/10.1056/NEJMoa2405182

Statins for the 'SMuRFLess But Inflamed': Silent Vascular Inflammation and the Challenge of Translational Science

https://doi.org/10.1016/j.jacbts.2025.101318

VERVE-101: A Promising CRISPR-Based Gene Editing Therapy That Reduces LDL-C and PCSK9 Levels in HeFH Patients

https://academic.oup.com/ehjcvp/article/10/2/89/7492807

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