In this episode, Jonathan Johnson, MD, and guest speakers, Cindy Miller, RN, and Ashley Collinsworth, ScD, MPH, highlight data showing that early initiation of negative pressure wound therapy with instillation and dwell—within the first day of treatment—can improve outcomes and reduce costs. Patients treated early had shorter hospital stays, fewer procedures, and over $10,000 in savings per admission. Tune in as Dr. Jonathan Johnson (Dr. Wounds) and guests discuss how optimizing timing can elevate efficiency and healing in wound care.