The UK has changed its guidance for the AstraZeneca Covid vaccine following reported rare blood clots. Younger recipients will now be offered an alternative dose but the British medical authorities say the benefits still outweigh any risks. The European Medical Agency has acknowledged a possible link between the vaccine and the side effects but has not age-restricted the jab on the Continent. In the U.S., the S&P 500 hits another record close buoyed by the Federal Reserve’s March minutes optimism about the country’s outlook. President Biden has indicated that he is willing to debate and compromise over his corporate tax plan with some reports suggesting that 25 per cent could be the best middle-ground figure.

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