Dr RR Baliga's "Got Knowledge Doc" Podkast

Sugar Switches: HFpEF's Hidden Code 🧩🫀🧬


Listen Later

🧠💓 Just read a fascinating new study in Cell Metabolism (July 2025): dislocation of hexokinase 1 from mitochondria increases O-GlcNAcylation in endothelial cells — a hidden driver of HFpEF!

Reversing this sugar-tagging with OGA overexpression or OGT inhibition restores heart function in mice. Precision metabolism meets cardiology. 🔬❤️‍🔥

#HFpEF #OGlcNAcylation #EndothelialDysfunction #CardioResearch #MetabolicTherapeutics #CellMetabolism

...more
View all episodesView all episodes
Download on the App Store

Dr RR Baliga's "Got Knowledge Doc" PodkastBy Dr RR Baliga, MD, MBA

  • 5
  • 5
  • 5
  • 5
  • 5

5

6 ratings


More shows like Dr RR Baliga's "Got Knowledge Doc" Podkast

View all
This Week in Cardiology by Medscape

This Week in Cardiology

894 Listeners

The Curbsiders Internal Medicine Podcast by The Curbsiders Internal Medicine Podcast

The Curbsiders Internal Medicine Podcast

3,374 Listeners

The Mel Robbins Podcast by Mel Robbins

The Mel Robbins Podcast

21,499 Listeners