Talk Python To Me

Talk Python To Me

By Michael Kennedy

Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. We dive
deep into the popular packages and software developers, data scientists, and incredible ... more

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Best of Talk Python To Me

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  1. Number 1: #563: Getting Started with Rust as Python Devs

    Lint the entire CPython code base from scratch. It takes 0.3 seconds. Three blinks of an eye. That is ruff, and it is written in Rust. So are Pydantic, Polars, uv, and Granian. Rust shows up in Python three ways: tools that happen to be Rust, libraries Python imports, and servers that run Python inside Rust. This is Rust for Python developers, not Rust experts. Christopher Trudeau is back on Talk Python to discuss Rust and his latest course Up and Running with Rust. The core rule is that only one thing can own a value at a time. Pass it around freely in Python and the garbage collector cleans up. Do that in Rust and it will not compile. Episode sponsors Sentry Error Monitoring, Code talkpython26 Python in Production Talk Python Courses Links from the show Up and Running with Rust course: training.talkpython.fm Rust: rust-lang.org pydantic: pydantic.dev ruff: docs.astral.sh granian: github.com By example: doc.rust-lang.org rust-lang.org: rust-lang.org rustup.rs: rustup.rs crates.io: crates.io main.rs: main.rs PyO3: github.com https://github.com/ritwiktiwari/awesome-python-rs: github.com ty: docs.astral.sh pyrefly: pyrefly.org uv: github.com polars: pola.rs Watch this episode on YouTube: youtube.com Episode #563 deep-dive: talkpython.fm/563 Episode transcripts: talkpython.fm Theme Song: Developer Rap ๐Ÿฅ Served in a Flask ๐ŸŽธ: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @[email protected] X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @[email protected] Michael on X.com: @mkennedy

    1h 11min
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  2. Number 2: #562: DuckLake: The Lakehouse That's Just SQL and Parquet

    How many files does your query read before it reads any data? On some data lakes, you go through JSON and metadata files first, just to learn which Parquet files matter. DuckLake asks one SQL question instead. The metadata lives in a real database. The data stays in plain Parquet. That's the entire format. Pedro Holanda joined DuckDB in 2018, when it was still a research prototype at CWI. He's the lead DuckLake developer. Guillermo Sanchez Dionis works on DuckLake and the new Quack protocol. With Quack as the catalog, DuckLake handles 200 transactions a second under heavy contention. No other open table format comes close. Episode sponsors Six Feet Up Talk Python Courses Links from the show Guests Pedro Holanda: pedroholanda.org Guillermo Sanchez: linkedin.com PhD on progressive indexes: ir.cwi.nl SQLite: www.sqlite.org Litestream: litestream.io boring hardware: talkpython.fm DuckDB: duckdb.org episode 491: talkpython.fm Iceberg: iceberg.apache.org manifesto: ducklake.select DuckLake: ducklake.select spec: ducklake.select this diagram: blobs.talkpython.fm Data inlining: ducklake.select ducklake-dataframe: github.com Polars course: training.talkpython.fm CSV parser: duckdb.org Zero-copy Arrow: duckdb.org ART index: duckdb.org async I/O: duckdb.org v1.0: ducklake.select Git-like branching: ducklake.select Watch this episode on YouTube: youtube.com Episode #562 deep-dive: talkpython.fm/562 Episode transcripts: talkpython.fm Theme Song: Developer Rap ๐Ÿฅ Served in a Flask ๐ŸŽธ: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @[email protected] X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @[email protected] Michael on X.com: @mkennedy

    1h 12min
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  3. Number 3: #561: TonIO, a Multi-threaded Async Runtime for Python

    How many cores does your machine have, 10, 18? Your async Python code uses just one of them. That isn't a bug in asyncio. That's the design, and optimizing event loops to be faster by 20% doesn't change it. So Giovanni Barillari started over. Joe is the creator of Granian, the Rust-based server that powers Talk Python. His new project is TonIO, an async runtime written from scratch for free-threaded Python. Real threads, a handful of primitives instead of asyncio's pile of them, and it flat out refuses to start if the GIL is on. Episode sponsors Sentry Error Monitoring, Code talkpython26 Python in Production Talk Python Courses Links from the show Guest Giovanni Barillari: github.com Granian: github.com Hyper: github.com Free threaded Python: docs.python.org Sort of: labs.quansight.org did a whole course: training.talkpython.fm uvloop: github.com rloop: github.com TonIO: github.com your EuroPython 2026 talk: www.youtube.com Michael's Cutting Python Web App Memory Over 31% Article: mkennedy.codes Watch this episode on YouTube: youtube.com Episode #561 deep-dive: talkpython.fm/561 Episode transcripts: talkpython.fm Theme Song: Developer Rap ๐Ÿฅ Served in a Flask ๐ŸŽธ: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @[email protected] X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @[email protected] Michael on X.com: @mkennedy

    1h 16min
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  4. Number 4: #560: Building a Research OS: From Django to 30,000 Samples

    In 2020, a gastroenterologist in Glasgow did the math on his new research study and came up with 30,000 samples, arriving over two years from three cities and a dozen hospitals. He asked around about how researchers keep track of that. The answer was Microsoft Excel. Shaun Chuah had written some HTML by hand in Notepad back in high school and that was about the whole of his programming experience, so he opened the Django tutorial and started reading. Six years later that app is Foundry120, holding 10 terabytes of clinical and genomics data with an agentic AI running on top of it. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Talk Python Courses Links from the show Guest Shaun Chuah: github.com Up and Running with Rust Course: talkpython.fm Foundry120: www.foundry120.com Designing Data Intensive Applications: www.oreilly.com Microsoft Foundry: ai.azure.com ChatIBD: www.chatibd.com Blog: shaunchuah.github.io @drshaunchuah: x.com github.com/shaunchuah: github.com Watch this episode on YouTube: youtube.com Episode #560 deep-dive: talkpython.fm/560 Episode transcripts: talkpython.fm Theme Song: Developer Rap ๐Ÿฅ Served in a Flask ๐ŸŽธ: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @[email protected] X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @[email protected] Michael on X.com: @mkennedy

    1h 3min
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  5. Number 5: #559: 12 Things You Should (and Shouldn't) Do in AWS

    Your site is down. It's 3am. Is it a bug, a bill, or a breach? You can't tell yet, and everyone is watching you find out. Matt Lea has spent fifteen years being the person companies call when an outage is costing them real money per hour, and his whole argument is that everything you'd want in that moment gets decided months earlier, on ordinary afternoons, when someone chose the convenient thing. We walk his top twelve dos and don'ts in AWS - infrastructure as code, IAM roles instead of access keys, private subnets, no wildcards, no public buckets - and I push on which of them actually matter if you're one person on a small VPS. Then we get to Cloud War Games, where Matt breaks things on purpose so your team's first real incident isn't their first incident. Let's get into it. Episode sponsors Sentry Error Monitoring, Code talkpython26 Talk Python Courses Talk Python Courses Links from the show Guest Matt Lea: linkedin.com Talk Python Certificates: training.talkpython.fm/certificates Schematical: schematical.com CloudWarGames.com: cloudwargames.com Zero to Hero on AWS Security: www.oreilly.com Repo: github.com Custom Wheel Offset: customwheeloffset.com 2012 TechCrunch Disrupt Hackathon: techcrunch.com tech comics: schematical.com shhgit: github.com Zero Trust in 200ms: Implementing Identity-Per-Transaction: us.pycon.org Coolify: coolify.io returned to full GA Nov 2025: aws.amazon.com Signed URLs/cookies: docs.aws.amazon.com Cloudflare: www.cloudflare.com Bunny Shield: bunny.net Cloud War Games One: www.youtube.com Cloud War Games Two: www.youtube.com LinkedIn: linkedin.com YouTube: youtube.com KnocKnoc: knocknoc.io Watch this episode on YouTube: youtube.com Episode #559 deep-dive: talkpython.fm/559 Episode transcripts: talkpython.fm Theme Song: Developer Rap ๐Ÿฅ Served in a Flask ๐ŸŽธ: talkpython.fm/flasksong ---== Don't be a stranger ==--- YouTube: youtube.com/@talkpython Bluesky: @talkpython.fm Mastodon: @[email protected] X.com: @talkpython Michael on Bluesky: @mkennedy.codes Michael on Mastodon: @[email protected] Michael on X.com: @mkennedy

    1h 8min
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