Lipids remain central to cardiovascular prevention.

The 2026 ACC/AHA Dyslipidemia Guideline introduces several important shifts:

• PREVENT equations replace older ASCVD risk calculators

• Lipoprotein(a) measurement recommended at least once in all adults

• ApoB helps identify residual lipoprotein risk

• Coronary artery calcium scoring refines treatment decisions

• LDL-C targets return, with

• South Asian ancestry is treated as a "risk enhancer,"

Earlier identification and aggressive risk reduction remain the cornerstone of preventing atherosclerotic cardiovascular disease.

Reference: Blumenthal RS et al. JACC 2026.