Dr. Drew opens the show today by telling Adam that he will be going to The White House to speak with a group of people that the administration is gathering to have a discussion about the opioid epidemic in the country today. The conversation then turns to Adam's practice of jumping in his cold pool as well as the somewhat famous video of Adam's son Sonny attempting a cold plunge of his own, much to Lynette's dismay. They also turn to the phones and speak with a caller who draws correlations between behaviors exhibited in orphaned elephants and orphaned humans.

Adam opens the show asking Drew about the health of his eyes and the abundance of eye drops that he is now using as he recovers from his recent eye procedure. The conversation then turns to the recent tragedy in Parkland, Florida and the actions of armed deputy Scot Peterson who arrived outside the school but never entered to confront the gunman. After discussing Peterson's version of events as provided by his attorney, the guys examine what they would have liked to have happened as the tragedy unfolded. They also speak to a caller whose daughter recently learned that the father she knows is not her biological father and is looking for advice on how to handle it.

Adam and Dr. Drew open up the show discussing an Amazon documentary series that Drew has been watching on the live of Hugh Hefner and the guys explore his actions over the years with the benefit of hindsight. They then turn to the phones and speak to a caller whose father was recently diagnosed with cancer and underwent treatment but is unwilling to go back for further treatment. They Also speak with a caller who wants to give Adam a new title.

Adam and Drew open the show discussing Adam's philosophy around people screwing things up that he could easily screw up himself. The conversation then turns to experiences Adam has had in the past with letting those around him set their own deadline to accomplish a task only to watch the deadline go by with the task remaining unaccomplished. They then turn to the phones and speak to a variety of callers including one who is going through a divorce and considering changing careers, and another who wants to defend Kanye West to Adam.

Adam and Dr. Drew open the show discussing the current phenomena of having an overload of really great content and finding it hard to keep up, which leads Adam into a conversation that ultimately ends with his recalling and showing Drew a set of TV commercials from the late 1970s. The guys then turn to the phones and speak to a caller who is worried that his erectile disfunction issues may be a result of his consumption of porn, and another who is wondering about the interactions between SSRIs and MDMA.

Adam and Drew go straight to the phones today and speak to a few callers starting with one who is a recovering addict who is worried about relapsing, and another who wants to talk about the recent tragedy in Parkland, Florida. They also have an in-depth conversation about a wide range of topics relating to drugs with a police officer who called in to ask if Drew things that the proliferation of Adderall has led to an uptick in meth use.

Adam opens the show telling Dr. Drew about some issues he's been having with family despite all of his efforts to the contrary. Adam also has Drew help him explore the psychology behind some of the responses he gets when he asks questions about situations and in answer only gets the situation repeated back at him. The guys then turn to the phones and speak to a few callers including one wanting to defend golfing, another wondering about how the questions on this show differ from the Loveline days, and more.

Adam and Dr. Drew open the show discussing the things that people, including his mother, spend time being obsessed with and how they shift over the years from non-topics like salt back in the day and vaping today. They also turn to the phones and speak to a caller who is wondering at what point one should start to worry about the way he feels and how to differentiate feeling miserable from true depression. As the how wraps up Drew brings up the idea that our country has gotten to a point where much of our society is spiritually bankrupt and people aren't focusing enough on nourishing themselves in a spiritual manner.

Adam and Dr. Drew open the show discussing Drew's renewed interest in lifting heavy weights and Adam's recent apathy towards the practice. Drew also tells Adam about a recent test he did with Fitness Genes wherein he learned a lot about what kind of exercise he should be doing for his body. They then turn to the phones and speak to a caller who is wondering if he should break up with his girlfriend who is also the mother of his daughter. They also speak to a caller whose mother was almost murdered by her step-father, another who fears his father is depressed and more.

Adam and Dr. Drew open the show discussing the LA Times attack piece on Dr. Drew that they teased on yesterday's show before turning to the phones and speaking to a caller who is recovering from alcohol and has been noticing some strange behavior from those around him. They also speak to a caller whose recovering child has specific vivid memories of things that in fact never actually happened or didn't happen to way he remembers. Adam and Drew then discuss a problem that Adam's been having around the house with his kids and his dog Phil.