Howie and Harlan discuss a breakthrough pain medication, studies on AI-assisted medicine, the explosion of sports gambling, and the health consequences of the shutdown of USAID.

Links:

A First-in-Class Painkiller

"F.D.A. Approves Drug to Treat Pain Without Opioid Effects"

"FDA Approves Novel Non-Opioid Treatment for Moderate to Severe Acute Pain"

"Peripheral Sodium Channel Blocker Could Revolutionize Treatment for Nerve Pain"

"Alabama to Beijing… and Back: The Search for a Pain Gene"

AI Screening

"Screening performance and characteristics of breast cancer detected in the Mammography Screening with Artificial Intelligence trial (MASAI): a randomised, controlled, parallel-group, non-inferiority, single-blinded, screening accuracy study"

"3D mammograms show benefits over 2D imaging, especially for dense breasts".

"The Robot Doctor Will See You Now"

USAID and Foreign Aid

"Trump and Musk move to dismantle USAID, igniting battle with Democratic lawmakers"

"What USAID does, and why Trump and Musk want to get rid of it"

"The Status of President Trump's Pause of Foreign Aid and Implications for PEPFAR and other Global Health Programs"

"The Case For Global Health Diplomacy"

The Super Bowl and Legalized Sports Gambling

"Super Bowl LIX: Betting By The Numbers"

"Americans expected to bet $1.39B legally on Super Bowl 2025"

"Record 68 million people plan on making Super Bowl bets"

"Gambling problems are mushrooming. Panel says we need to act now."

COVID and Flu

"The U.S. Is Having Its Mildest Covid Winter Yet"

"Estimated Vaccine Effectiveness for Pediatric Patients With Severe Influenza, 2015-2020"

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