By Yale School of Management
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The podcast currently has 153 episodes available.
Howie and Harlan are joined by Vin Gupta, a physician, a medical analyst for NBC News, and the chief medical officer of Amazon Pharmacy. Harlan reports on the Biden administration’s proposal to cover obesity drugs with Medicare and Medicaid; Howie offers some reasons to be thankful.
Links:
Coverage of Obesity Medication
“White House Fact Sheet: Biden-Harris Administration Takes Latest Step to Lower Prescription Drug Costs by Proposing Expanded Coverage of Anti-Obesity Medications for Americans with Medicare and Medicaid”
“The (Minimum) Emergency Savings Needed in America’s 50 Largest Cities”
“The implications of defining obesity as a disease: a report from the Association for the Study of Obesity 2021 annual conference”
“Expanded Medicare Coverage of Antiobesity Drugs May Cost Billions Each Year”
Harlan Krumholz: “Eligibility for Cardiovascular Risk Reduction Therapy in the United States Based on SELECT Trial Criteria: Insights From the National Health and Nutrition Examination Survey”
Vin Gupta
“Ozempic and Wegovy may help curb alcohol addiction, study suggests”
“Amazon Launches $5-a-Month Prescription Drug Plan in Further Healthcare Push”
“As Mail Order Pharmacies Continue to Climb in Customer Satisfaction, Chain Drug Stores Fall Behind, J.D. Power Finds”
“The Powerful Companies Driving Local Drugstores Out of Business”
“Amazon Purchase of One Medical Health Clinics Won’t Be Blocked by FTC”
Anthropic: Meet Claude
“A.I. Chatbots Defeated Doctors at Diagnosing Illness”
Reasons to be Thankful
“As Medicaid Unwinding Concludes in Most States, KFF Finds 25 Million Lost Medicaid Coverage but Enrollment is 10 Million Higher Than Pre-Pandemic Levels”
“Egypt has been declared malaria-free by the World Health Organization”
“FDA Approves First Gene Therapies to Treat Patients with Sickle Cell Disease”
“Novel pulsed field ablation offers patients safer and faster atrial fibrillation ablation”
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Howie and Harlan are joined by investor and entrepreneur Halle Tecco to discuss her work connecting the worlds of technology and healthcare, and her latest venture, which allows women to freeze their eggs for future use for free if they donate half of them to a couple in need. Harlan checks in from the annual meeting of the American Heart Association; Howie discusses his concerns about Robert F. Kennedy Jr.’s appointment as secretary of health and human services.
Links:
American Heart Association Meeting
“Tirzepatide Reduces LV Mass and Paracardiac Adipose Tissue in Obesity-Related Heart Failure”
“Intensive Lifestyle Intervention, Cardiac Biomarkers, and Cardiovascular Outcomes in Diabetes: LookAHEAD Cardiac Biomarker Ancillary Study”
“Accelerometer-Measured Sedentary Behavior and Risk of Future Cardiovascular Disease”
Halle Tecco
Halle Tecco: Blog
Halle Tecco: Investing in Digital Health Startups Course
“This power couple bought bitcoin in 2013, and just donated all their gains to a cancer hospital”
Rock Health
Natalist
Cofertility
RFK Jr.
“What to know about RFK Jr.’s views on food, vaccines, abortion, and the FDA”
“How a Kennedy built an anti-vaccine juggernaut amid COVID-19”
“With Trump coming into power, the NIH is in the crosshairs”
“RFK Jr.’s Inside Job”
“How RFK Jr.’s MAHA movement could shake up public health”
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Howie and Harlan are joined by Rahul Rajkumar, founder and CEO of Accompany Health, which provides a team of providers for patients who are on both Medicare and Medicaid. Harlan reflects on a visit to China and the healthcare ramifications of proposed legislation that would force U.S. biotech companies to cut ties with some Chinese partners. Howie provides an update on healthcare-related measures on state ballots in last week’s election.
Links:
China and the Biosecure Act
“Congress takes up a series of bills targeting China, from drones to drugs”
“U.S. Drugmakers Are Breaking Up With Their Chinese Supply-Chain Partners”
Accompany Health
Accompany Health
Medicare: Dual-Eligibles
Centers for Medicare & Medicaid Services: Dual Eligible Special Needs Plans
“Medicaid Enrollees by Enrollment Group”
“Justice Department sues to block UnitedHealth Group’s $3.3 billion purchase of Amedisys”
“10 Reasons Why Medicare Advantage Enrollment is Growing and Why It Matters”
Healthcare on the Ballot
“7 states vote to protect abortion rights, while efforts to expand access in Florida, Nebraska and South Dakota fail”
“Marijuana and Drug Policy on the Ballot”
“Massachusetts voters reject proposal to legalize certain psychedelic drugs”
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Howie and Harlan discuss health and healthcare headlines, including generational shifts in doctors’ approach to work, a promising vaccine for norovirus, the latest on the bird flu outbreak, and the struggles of corporate-backed primary care companies.
Links:
Norovirus
CDC: Norovirus
“Bivalent norovirus mRNA vaccine elicits cellular and humoral responses protecting human enteroids from GII.4 infection”
“Doctors trial world’s first mRNA vaccine against vomiting bug norovirus”
“Who Didn’t Get a Second Shingrix Shot? Implications for Multidose COVID-19 Vaccines”
Work-Life Balance
“Young Doctors Want Work-Life Balance. Older Doctors Say That’s Not the Job.”
“State of Women in Medicine: History, Challenges, and the Benefits of a Diverse Workforce”
Bird Flu
“CDC Confirms Human H5 Bird Flu Case in Missouri”
STAT: H5N1 Bird Flu
Primary Care Goes Corporate
“Why Large Corporations Are Entering Primary Care”
“Cigna Turns $739 Million Profit Despite $1 Billion Loss On VillageMD”
Prescription for the Future: The Twelve Transformational Practices of Highly Effective Medical Organizations
E. coli
“E. coli Outbreak Linked to Onions Served at McDonald’s”
“How disease detectives’ quick work traced deadly E. coli outbreak to McDonald’s Quarter Pounders”
CDC: Outbreaks of E. coli infections
Elon Musk’s Grok AI Platform
“Elon Musk wants you to submit medical data to his AI chatbot”
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Howie and Harlan are joined by Stephen Knight, president and managing partner of the healthcare and technology venture capital firm F-Prime Capital, to discuss his varied career and the breakthroughs he has helped enable. Howie and Harlan discuss AI in medicine and what a second Trump administration could mean for healthcare.
Links:
Respiratory Illnesses, AI, and the Physician Shortage
CDC: Respiratory Illnesses Data Channel
“Capabilities of Gemini Models in Medicine”
“Yale New Haven Health partners with AI company on ambient listening tech”
Stephen Knight
F-Prime Capital
Genentech
F-Prime Capital: Stories and Ideas
“How AIDS Activists Fought for Patients’ Rights”
VC: An American History
Bluebird Bio
F-Prime Capital: Orchard Therapeutics
Severe Combined Immunodeficiency
“Pfizer to Acquire FoldRx Pharmaceuticals”
Beam Therapeutics
Trump and Healthcare
Project 2025: Policy Agenda
“Robert F. Kennedy Jr.’s ‘Make America Healthy Again’ Draws Wellness Influencers to MAGA”
Video: Trump on Robert F. Kennedy Jr.
Robert F. Kennedy Jr. on X
Video: the Trump rally at Madison Square Garden
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Howie and Harlan are joined by Michael Sherling, a dermatologist and a founder of Modernizing Medicine, which aims to save doctors time with an intelligent, specialty-specific electronic health record. Harlan provides updates on COVID-19 variants and vaccines, and on the acquisition of CareBridge, which provides value-based home care for Medicaid patients. Howie explains why cases of pertussis—whooping cough—are increasing.
Links:
COVID-19 and CareBridge
Akiko Iwasaki, PhD
CareBridge Health
“The Accidental Entrepreneur: Brad Smith’s Journey From Politics to Business”
“America's Fastest-Growing Company Is Tackling the Greatest Challenge in Health Care | Inc.com”
“Elevance unit plans to buy CareBridge”
Michael Sherling and Modernizing Medicine
Modernizing Medicine
Dan Cane, CEO of Modernizing Medicine: “I sold my start-up for $1.6 billion. Here’s what I did next”
“Alumni team crafts electronic medical record that cuts down paperwork and saves time”
“Ambient AI Is Having Its ‘Moment’ In Healthcare”
Dawn Harris Sherling: Eat Everything
Pertussis
CDC: Whooping Cough
“Whooping Cough Is on the Rise, Returning to Pre-Pandemic Trends”
“Whooping cough spikes, especially among unvaccinated teens”
“Falling Vaccinations Contribute to Rising Pertussis Numbers”
Learn more about the MBA for Executives program at Yale SOM.
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Howie and Harlan discuss health and healthcare issues in the headlines, including a powerful—but dangerous—new gene therapy, racial disparities in excess deaths during the COVID pandemic, and the limited insurance coverage for highly effective new obesity drugs.
Links:
The Physician Shortage
“Opening the Door Wider to International Medical Graduates—The Significance of a New Tennessee Law”
“New Licensure Pathway for Some Internationally Trained Physicians”
“Brain-drain and health care delivery in developing countries”
“Talk of an Immigrant ‘Invasion’ Grows in Republican Ads and Speech”
Subspecialty Expertise from AI
“Towards Democratization of Subspeciality Medical Expertise”
Gene Therapy
“7 children developed blood cancer after Bluebird Bio gene therapy for rare neurological disease”
National Institute of Neurological Disorders and Stroke: Adrenoleukodystrophy
An AI Warning from a Nobel Laureate
Nobel Prize: Nobel Prize in Physics
“Why the Godfather of A.I. Fears What He’s Built”
“Unions Give Workers a Voice Over How AI Affects Their Jobs”
Conflicts of Interest and the Role of Peer Reviewers
“Medical journal peer reviewers are paid millions by industry, study finds”
“Does industry funding equal conflict of interest? Often it does, Yale authors claim”
COVID, Race, and Excess Deaths
“Racial and Ethnic Disparities in Age-Specific All-Cause Mortality During the COVID-19 Pandemic”
Insurance Coverage for GLP-1 Drugs
KFF: 2024 Employer Health Benefits Survey
“The Miracle Weight-Loss Drug Is Also a Major Budgetary Threat”
CDC: Adult Obesity Facts
Mothers in Medicine
“So Visibly a Mother”
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Howie and Harlan are joined by Max Laurans, a Yale neurosurgeon and hospital administrator, and a founder of the healthcare staffing company Nomad Health. Harlan discusses the problem of doctors giving too much weight to suggestions from AI; Howie celebrates a milestone in the campaign to eliminate trachoma, a common cause of preventable blindness in the developing world.
Links:
Automation Bias
“Some doctors are using public AI chatbots like ChatGPT in clinical decisions. Is it safe?”
“Measuring the Impact of AI in the Diagnosis of Hospitalized Patients: A Randomized Clinical Vignette Survey Study”
“Automation Bias and Assistive AI: Risk of Harm From AI-Driven Clinical Decision Support”
“Combining Human Expertise with Artificial Intelligence: Experimental Evidence from Radiology”
Max Laurans
Maxwell Laurans, MD, MBA, FAANS
Nomad Health: Travel Nurse and Travel Allied Health Jobs
2003 residency placements for Yale medical students
“Yale New Haven Hospital breaks ground on $838 million, 505,000 square foot Neurosciences Center”
“Hospitals across the U.S. face IV fluid shortage after Hurricane Helene”
Trachoma
Mayo Clinic: Trachoma
“Elimination of trachoma as a public health problem in India”
The Carter Center: Waging Peace. Fighting Disease. Building Hope
Learn more about the MBA for Executives program at Yale SOM.
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Howie and Harlan welcome Vivek Murthy, the 19th and 21st Surgeon General of the United States and a graduate of the Yale School of Medicine and the Yale School of Management. They talk about his campaigns to tackle parental stress, gun violence, and the dangers of social media, and the importance of communicating across political divides.
Links:
Parents Under Pressure: The U.S. Surgeon General's Advisory on the Mental Health & Well-Being of Parents
Youth Mental Health: The Surgeon General’s Advisory
Yale School of Medicine | Auguste Fortin VI, MD, MPH, MACP
Vivek Murthy: “Surgeon General: Why I’m Calling for a Warning Label on Social Media Platforms”
Firearm Violence: A Public Health Crisis in America: The Surgeon General’s Advisory
The Surgeon General’s 1964 report on smoking and health
Vivek Murthy at Yale College Class Day Exercises
Health Misinformation: The U.S. Surgeon General’s Advisory on Building a Healthy Information Environment
Social Media and Youth Mental Health: The Surgeon General’s Advisory
Log Off Movement
“Fetterman, Britt Introduce Bill to Require Mental Health Warning Labels on Social Media Platforms”
“The Outrage Industrial Complex”
Instagram: Vivek Murthy and his family at his swearing-in
Learn more about the MBA for Executives program at Yale SOM.
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Howie and Harlan discuss recent headlines, including the latest round of COVID and flu vaccines, a lousy report card for the U.S. healthcare system, and a rare case of swine flu. Plus: Howie investigates a mysteriously escalating pharmacy bill.
Links:
COVID and Flu Vaccines
CDC FluView: Weekly US Influenza Surveillance Report: Key Updates for Week 36, ending September 7, 2024
CDC: Staying Up to Date with COVID-19 Vaccines
“Florida discourages use of mRNA Covid vaccines in older adults”
“Florida’s New Covid Booster Guidance Is Straight-Up Misinformation”
CDC: COVID Data Tracker
A Failing Grade
“Mirror, Mirror 2024: A Portrait of the Failing U.S. Health System”
CMS Health Equity Conference
“What is Driving Widening Racial Disparities in Life Expectancy?”
Swine Flu
“Minnesota reports 2 H3N2v flu infections in fairgoers”
Shohei Ohtani
“Shohei Ohtani reaches 50-50 in spectacular style as Dodgers clinch postseason berth”
“The Shohei Ohtani Goal Matrix”
Baseball Almanac: A Definition of 50-50 Club
Drug Prices
Mayo Clinic: Flecainide
“Column: Less choice, higher prices feared in CVS’ takeover of health insurer Aetna”
“How to Save Money on Your Prescription Drugs”
Brain Age
“Brain clocks capture diversity and disparities in aging and dementia across geographically diverse populations”
“Brain aging patterns in a large and diverse cohort of 49,482 individuals”
“Associations between alcohol consumption and gray and white matter volumes in the UK Biobank”
“Environmental Cardiology: Studying Mechanistic Links Between Pollution and Heart Disease”
AirPods as Hearing Aids
“FDA Authorizes First Over-the-Counter Hearing Aid Software”
Oak Street Health
Department of Justice: Oak Street Health Agrees to Pay $60M to Resolve Alleged False Claims Act Liability for Paying Kickbacks to Insurance Agents in Medicare Advantage Patient Recruitment Scheme
“CVS Reaches $10.6 Billion Deal to Buy Clinic Owner Oak Street Health”
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