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🔍 Two influential viewpoints just dropped in JAMA Cardiology on aortic valve replacement (AVR) in asymptomatic severe aortic stenosis (AS).
đź«€ Lindman, Braunwald & Pellikka argue that the time has come to move from "watchful waiting" to early intervention (SAVR/TAVR), citing RCTs showing reduced stroke, heart failure hospitalization, and unplanned CV events.
⚖️ Hillis, McCann & Newby counter that the evidence is not yet strong enough for a universal shift—pointing to trial limitations, competing risks in older patients, and the danger of unnecessary procedures.
✨ The debate is clear: Act early or wait carefully?
This conversation is shaping the future of valve guidelines and clinical practice.
By Dr RR Baliga, MD, MBA5
66 ratings
🔍 Two influential viewpoints just dropped in JAMA Cardiology on aortic valve replacement (AVR) in asymptomatic severe aortic stenosis (AS).
đź«€ Lindman, Braunwald & Pellikka argue that the time has come to move from "watchful waiting" to early intervention (SAVR/TAVR), citing RCTs showing reduced stroke, heart failure hospitalization, and unplanned CV events.
⚖️ Hillis, McCann & Newby counter that the evidence is not yet strong enough for a universal shift—pointing to trial limitations, competing risks in older patients, and the danger of unnecessary procedures.
✨ The debate is clear: Act early or wait carefully?
This conversation is shaping the future of valve guidelines and clinical practice.

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