the bioinformatics chat

By Roman Cheplyaka

What's the bioinformatics chat about?

A podcast about computational biology, bioinformatics, and next generation sequencing.

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#43 Generalized PCA for sin...


Will Townes proposes a new, simpler way to analyze scRNA-seq data with unique molecular identifiers (UMIs). Observing that such data is not zero-inflated, Will has designed a PCA-like procedure inspired by generalized linear models (GLMs) that, unlike the standard PCA, ...

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