Chelsea Cirruzzo, Washington correspondent for STAT News, talks about the White House press conference on autism, acetaminophen, and immunizations, plus the results of last week's meeting of the federal advisory committee on vaccines, and the confusion over federal, state and local public health rules.

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Richard Gowan, International Crisis Group's director of UN and Multilateral Diplomacy, shares what to expect at the UN General Assembly, including what President Trump may say in his Tuesday address, the war in Gaza and other crises and the role of the United Nations globally.

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In a new memoir, Yusuf Islam, also known as the singer-songwriter Cat Stevens, writes about how converted his faith after a near-death experience. Listeners call in to share what has prompted them to change their faith.

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Daniel Di Martino, fellow at the Manhattan Institute whose research focuses on immigration, and Amy Torres, executive director of the New Jersey Alliance for Immigrant Justice, debate the issues around sanctuary laws in the New York City mayor's race and the New Jersey governor's election.

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Three of our favorite segments from the week, in case you missed them.

How Trump May Be Changing the Elections Process (First) | AI in the Job Market (Starts at 51:0 0) | Your Family's 'Secret Language' (Starts at 1:18:00)

If you don't subscribe to the Brian Lehrer Show on iTunes, you can do that here.

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Nate Soares, president of the Machine Intelligence Research Institute and the co-author (with Eliezer Yudkowsky) of If Anyone Builds It, Everyone Dies: Why Superhuman AI Would Kill Us All (Little, Brown and Company, 2025), talks about why he worries that AI "superintelligence" will lead to catastrophic outcomes, and what safeguards he recommends to prevent this.

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A new Siena poll shows a (slight) majority of New Yorkers said the state is on the right track, while 59% of respondents thought the U.S. is heading in the wrong direction. New Yorkers call in to share what they think is going well in the state compared to the rest of the country.

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Brooklyn Borough president Antonio Reynoso talks about why he's now supporting the plan to redevelop Brooklyn's Marine Terminal ahead of a pivotal vote on the project.

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Elie Honig, senior legal analyst at CNN, New York Magazine columnist, former state and federal prosecutor and author of several books, including When You Come at the King: Inside DOJ’s Pursuit of the President, From Nixon to Trump (Harper, 2025), explores investigations by the Department of Justice of presidents and other high-ranking officials throughout the years, and how the system may be tested during Trump's second presidency.

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As the Atlantic Festival takes place in NYC, staff writers and panelists Ashley Parker, staff writer at The Atlantic, former Washington Post White House bureau chief, and Adam Serwer, staff writer at The Atlantic, preview their panels and discuss the latest from the White House particularly the events after the the assassination of Charlie Kirk.

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