The Tampa Bay Buccaneers head into Week 11 coming off a frustrating loss to the New England Patriots, a game defined by explosive plays that flipped the momentum and exposed major issues on defense. Despite Baker Mayfield throwing for 273 yards and three touchdowns with no turnovers, Tampa Bay surrendered four massive scoring plays — runs and passes of 55 yards or more — that ultimately cost them the game. Young weapons like Emeka Egbuka and Tez Johnson stepped up, the run game looked alive, and the offense played well enough to win, but defensive breakdowns, communication lapses, missed tackles, and injuries on all three levels of the defense left the Bucs scrambling. With key contributors banged up and depth being tested, the Buccaneers suddenly find themselves trying to regroup while still holding onto first place in the NFC South. Now the focus shifts to a tough matchup against the Buffalo Bills, a team known for speed, physicality, and a hostile home environment that punishes mistakes. Tampa Bay enters this week needing a defensive reset, cleaner coaching execution, and clarity on injured starters before facing an AFC contender that can stretch the field just like New England did. The Bucs showed offensive growth, resilience, and flashes of potential, but the Bills matchup represents a critical moment — a gut-check opportunity to prove they can rebound, tighten the defense, and keep control of the division race. The next game could define the direction of Tampa Bay’s 2025 season and determine whether this loss becomes a turning point or the beginning of a slide.