The Lab Report

When people hear the word ‘cannabinoid’, what usually comes to mind is marijuana (also known as cannabis) or CBD oil (cannabidiol). But did you know, the body creates its own natural cannabinoids using the endocannabinoid system? This endocannabinoid system is a mysterious and complex interplay of chemical messengers throughout the brain and body which in essence contributes to our body’s homeostasis. It regulates a broad array of physiological processes including pain, mood, sleep, inflammation, appetite, and more. Rather than relying on marijuana or CBD products, Dr. Joe Feuerstein teaches that there are ways to boost the endocannabinoid system naturally. As a nationally recognized and award-winning physician and researcher in the field of botanical medicine and nutrition, Dr. Joe has co-written a best-selling book on how to do just that.

Today Dr. Joe Feuerstein tells us what the endocannabinoid system is and why you should care. He also outlines various herbal and natural ways to boost the endocannabinoid system for optimal health.

Today on The Lab Report:

• 4:15 Meet Dr. Joe Feuerstein and hear about his amazing career
• 10:50 What are cannabinoids and why should we care?
• 14:05 Natural drivers to optimize the endocannabinoid system
• 19:30 The interaction between the HPA axis and the endocannabinoid system
• 21:00 Anecdotal improvements using the Cannabinoid Cookbook
• 23:00 Omega-6’s, anandamide and 2-AG, ‘cannabinoid resistance,’ chocolate
• 26:00 Gut-brain axis and the endocannabinoid system
• 27:40 Endocannabinoid deficiency, Cannabinoid Cookbook, Condition Kitchen
• 30:50 Using GI Effects actionable intelligence for microbiome modulation
• 39:20 Joe’s take on trendy diets
• 42:45 Where can we go to follow and work with Dr. Joe
• 44:45 The Fireball

Additional Resources:

Dr. Joe Feuerstein's website

The Cannabinoid Cookbook

Dr. Joe's Man Diet

Dr. Joe's YouTube channel

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Many of us think of adipose tissue as just a place to store excess fat to be used for energy. However, adipose tissue is very biologically active and secretes some important hormones and mediators called adipokines. These messengers help regulate glucose and lipid metabolism, control hunger, and affect insulin levels. That being said, ALL of our hormones work together like a symphony – cortisol, thyroid hormones, sex hormones, and don’t forget the adipokines.

In today’s episode, we discuss important bioactive messengers created by our fat tissue (leptin and adiponectin), how they affect us systemically, and strategies to optimize them.

Today on The Lab Report:

• 3:40 Adipose tissue, adipokines, and types of fat
• 7:40 What are adipokines?
• 10:25 Adiponectin does great things
• 13:00 How to increase adiponectin
• 14:20 Better Know a Biomarker – Leptin!
• 17:40 Obesity and leptin resistance
• 19:25 Treating leptin resistance
• 21:35 Leptin vs. ghrelin
• 23:15 Adiponectin/leptin ratio

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

The commensal bacteria in the gut microbiome are responsible for so many important functions. Their influence is far-reaching as it relates to overall health. Research shows us that the more diverse that community of bacteria is, the more beneficial it is to systemic health. But what does diversity mean and how do we measure it? There are many calculations used when it comes to diversity of the microbiome, and they can sometimes give differing information. It’s important to understand what’s being measured in order to clinically correlate the result.

In today’s episode, we discuss the industry standard Shannon Diversity Index as measured on Genova’s brand new Microbiomix profile.

Today on The Lab Report:

• 3:15 Better Know a Biomarker: Shannon Diversity Index
• 6:00 Evenness and Richness
• 7:30 Alpha vs. beta diversity
• 10:05 Who’s Claude Shannon?
• 13:00 Get Outta Here!
• 15:50 Simpson vs. Shannon Index
• 17:40 The numerical score
• 19:45 Improving the diversity score

Additional Resources:

GI Effects with Microbiomix

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

The NutrEval Profile is Genova’s most comprehensive nutritional assessment providing a framework of core nutrients in the areas of antioxidants, B-vitamins, digestive supports, essential fatty acids, and minerals. This functional evaluation is aimed at assessing nutrient insufficiencies and biochemical individuality. In the Medical Affairs department, we are privileged to speak with clinicians every day to interpret test findings in clinical context, answer general questions about testing, and dive into the latest literature to expand our understanding too.

On today’s episode, we address the top 5 most frequently asked questions about the NutrEval. Although we are focusing on the NutrEval, these questions and answers can also apply to our other nutritional testing as well.

Today on The Lab Report:

• 3:40 Do I need to stop supplements to perform testing? If so, for how long?
• 7:30 How does urinary creatinine affect findings?
• 11:00 What do the neurotransmitter metabolites tell us about the brain?
• 15:00 How do I interpret a NutrEval report that is released in two parts?
• 17:25 If the direct RBC magnesium result is normal, how is there still a magnesium recommendation on the nutrient recommendation page? – Similarly, if my serum B12 level is normal, why are there recommendations for more on the NutrEval?

Additional Resources:

NutrEval

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

There are very few key opinion leaders that hold extensive certifications in functional and integrative medicine who not only lecture, mentor, and teach but also continue to practice full-time and harness decades of clinical expertise like Dr. Filomena Trindade. An internationally sought-after speaker, and mentor to hundreds of clinicians, Dr. Trindade continually scours literature for the latest research on hormonal and metabolic health. Her latest focus has been cardiovascular disease.

On today’s episode, we dive into the latest insights regarding cardiovascular disease in women with Dr. Filomena Trindade. We discuss the interplay between women’s hormones, insulin resistance, and metabolic health.

Today on The Lab Report:

• 4:20 Meet Dr. Filomena Trindade
• 6:40 State of the evidence regarding women’s health and cardiovascular disease
• 11:25 Atypical lipid patterns in hormone dysregulation
• 14:20 Discrepancies in pain patterns – men vs. women
• 16:30 Atherogenesis and inflammation in women
• 19:50 The role of SNPs and hormone regulation
• 22:45 Perimenopause and menopause mechanisms in heart disease
• 25:00 Metabolic health and the hormone symphony
• 30:00 Biomarkers, visceral adiposity, and insulin resistance
• 35:25 Radiologic scanning, body impedance measurement, and physical exam
• 38:00 Increasing muscle mass vs. decreasing carbohydrates
• 41:10 Mentorship for new clinicians
• 46:30 The Fireball  

Additional Resources:

drtrindade.com

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Inflammation is your body’s way of protecting itself from infection, injury, or other insults. Chemical signaling molecules called ‘eicosanoids’ are responsible for creating pain, heat, swelling, and redness. Eicosanoids are made from fatty acids, or dietary fats. We’ve all heard of fish oil and omega-3s being important when it comes to lowering inflammation. But why?

In today’s episode, we break down the inflammatory cascade, explain how fatty acids are involved, and we answer the question ‘What in the world is an eicosanoid!?’

Today on The Lab Report:

• 3:20 What are eicosanoids?
• 6:05 Fatty acids and the inflammatory cascade
• 9:10 Lipoxygenase (LOX) and cyclooxygenase (COX)
• 10:00 The COX eicosanoids – prostanoids and thromboxane 
• 12:10 Leukotrienes, lipoxins, resolvins, and LOX
• 13:15 Aspirin, fish oil, and heart disease
• 16:30 Question of the Day
  • How should we measure fatty acids?

Additional Resources:

NutrEval

Essential & Metabolic Fatty Acids - Bloodspot

The omega-3 index as a risk factor for coronary heart disease

 Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Dr. Dwayne Jackson has spent decades in medicine and physiology. He lectured and taught at some of the finest universities in the world. In addition to academia, Dr. Jackson has been a staple in the fitness industry - both as an athlete and trainer. He is recognized internationally for his award-winning research which has shaped our understanding of chronic stress and its impact on immunity, inflammation, and mental health.

In today’s episode, Dr. Dwayne Jackson combines his vast knowledge of physiology with his long career in the fitness industry to help us cut through some of the noise related to nutrition, supplements, and mental-emotional stressors.

Today on The Lab Report:

• 4:00 Meet Dr. Dwayne Jackson – his career in academia and his reason for leaving
• 8:25 Path from dialysis to kidney transplant
• 14:40 Benefits of creatine supplementation and concern around kidney disease
• 20:40 The most over-hyped supplements
• 22:10 Recovery, sustained efforts, and stress on the body
• 25:40 Beyond protein – micronutrients, antioxidants, and balanced diets for performance
• 31:45 Endurance athletes, cortisol, gut health, and burnout
• 34:45 Body dysmorphia in elite athletes
• 41:00 Beyond athletes - working with patients with chronic illness
• 45:40 Creating consistency and working with Dr. Jackson
• 50:00 The Fireball

Additional Resources:

Dr.DwayneJackson.com

@drdnjackson

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Amber Shaw is a Mind & Body Transformation Expert and the Founder of The Wellness Revolution. She works with women over the age of 40 to empower them to rediscover their confidence and create a sustainable lifestyle. Amber’s approach fosters consistency, accountability, and kindness. Women can be quite hard on themselves rather than show self-love. Shifting hormones, the demands of family and career, and a very confusing diet landscape can all be difficult to navigate. This is where Amber Shaw chose to build her career.

On today’s episode, Amber Shaw talks about helping women heal their relationship with food and themselves while empowering them to transform their lives, love their bodies, and create lasting results.

Today on The Lab Report:

• 3:30 Meet Amber Shaw and hear her inspiring story
• 13:45 Raising children in a body-shame culture
• 17:10 Kindness, self-love, and shifting that mentality
• 21:00 Stop tying weight and metrics to self-esteem
• 23:40 Fostering consistency, not perfection
• 28:40 Avoiding diet camps, calories in – calories out, deprivation
• 33:00 Menopause, peri-menopause – old tricks no longer work
• 37:00 Work with Amber Shaw – sorry guys, women only
• 39:30 The Fireball

Additional Resources:

AmberShaw.com

The Wellness Revolution Podcast

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Inflammatory bowel disease or IBD is an umbrella term to describe chronic inflammatory disorders of the GI tract – most commonly Crohn’s disease and ulcerative colitis. Medications, nutritional therapies, and lifestyle modifications are all used to control symptoms and keep patients in remission. However, sometimes surgical intervention is needed. Dr. Elizabeth Raskin is an award-winning colorectal surgeon and the Surgical Director of one of the leading IBD programs in the country – the Hoag Margolis Family IBD Program. This team-based, multidisciplinary approach to helping patients with IBD addresses the medical, nutritional, and psychosocial components to these diseases.

Today we speak with Dr. Elizabeth Raskin, one of the leading colorectal surgeons in the country. We hear about her unique approach to IBD - combining nutrition, functional medicine, mental, spiritual, and emotional support for better patient outcomes.

Today on The Lab Report:

• 3:30 Meet Dr. Raskin and hear about her dedication to healing the colon
• 9:30 Nutritional challenges with IBD patients
• 14:40 Pre-habilitation before surgery
• 17:05 Post-op advice for primary care clinicians
• 20:55 IBD prevalence
• 22:50 The microbiome and surgery – pre and post op support
• 30:20 Triggers of IBD
• 33:50 Personalized approach to Crohn’s disease
• 38:00 Endurance athletics and the gut
• 46:45 The Fireball

Additional Resources:

Hoag Margolis Family IBD Program

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Dr. Lauryn Lax is a Doctor of Occupational Therapy, Clinical Nutritionist, Functional Medicine Practitioner, Certified Personal Trainer, author, and journalist. With over 20 years of clinical and personal experience, she’s on a mission to help patients feel good - inside and out. But what sets Dr. Lauryn apart is her life-long journey of illness and healing. It’s a story of joy, pain, bravery, and survival. This journey has resulted in an empathic heart, a holistic philosophy, and tools that can transform lives.

In today’s episode, Dr. Lauryn Lax shares her incredible story of personal healing to help heal others. We discuss the gut’s relationship to mental-emotional state, breaking free of strict food rules, and how to use German New Medicine to uncover true root causes.

Today on The Lab Report:

• 4:50 Meet Dr. Lauryn Lax
• 6:00 The Story
• 21:30 Lessons learned – new insights
• 23:30 Food freedom and clean eating
• 28:30 Where to start? Nourish the gut
• 34:00 Mental-emotional work
• 39:00 The real root cause: German New Medicine
• 44:50 The Fireball

Additional Resources:

dr.lauryn.com

Dr. Lauryn's books

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.