The Lab Report

Zombie cells, scientifically known as senescent cells, are damaged or aged cells that refuse to die when they should. Instead, they linger in the body, releasing harmful chemicals that can trigger inflammation and accelerate aging. These cells have been linked to a range of age-related diseases, including arthritis, Alzheimer’s, and even cancer.

Dive into the eerie world of 'Zombie Cells' on our latest episode! Uncover how these undead cells wreak havoc in our bodies and what cutting-edge research reveals about their role in aging and disease.

Today on The Lab Report:

• 4:15 Cell turnover, apoptosis, and autophagy vs. zombie cells 
• 7:30 What triggers zombie cells to form and what are telomeres?
• 10:15 Age-related diseases and inflammation
• 12:15 Senolytics and strategies to clear zombie cells
• 17:30 Just practice naturopathic medicine
• 18:30 Rules to survive a zombie apocalypse

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Such a random topic – gray hair? The technical term for hair graying is canities – again, what a strange word. Who knew? The basic physiology of hair growth and coloration is not something we really think about, but your hair can be a reflection of underlying health or disease. We often talk about the aging process as a marker of oxidative stress -So too with your hair.

In this episode, we dive into the science of graying hair. From melanin loss to genetics to some surprising lifestyle connections, we separate fact from fiction and uncover the truth about your hair.

Today on The Lab Report:

• 3:40 Canities, melanin and hair color
• 7:25 Melanin in hair vs. skin, hair growth stages  
• 12:15 Aging and premature graying, oxidative stress
• 16:25 Nutrition, hormonal influences, inflammation, stress
• 18:20 Re-pigmentation???  Or at least delay graying
• 23:10 Question of the Day
  • How can Genova’s testing help?

Additional Resources:

Genova Connect

NutrEval

Metabolomix+

Endo+

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Hiccups- that annoying and at times, painful reflex that sneaks up on you when you least expect it, and sometimes refuses to leave. But what are they really? Is there an evolutionary reason we’ve developed this reflex? When should you be concerned? Can we prevent them?

In this episode, we break down the pathophysiology of hiccups (yes, there’s real science behind it) Knowing the science of why they occur, we can separate fact from fiction on how to cure them. From medical insights to strange home remedies, we’re getting to the root of the world’s most inconvenient reflex. 

Today on The Lab Report:

• 3:45 Hiccups – the diaphragm and phrenic nerve
• 6:30 Pathophysiology of the hiccup and evolution of this reflex
• 9:30 Diet and lifestyle hiccup triggers
• 11:00 The rhythmic reflex arc
• 13:40 When should you be concerned?
• 15:50 Common cures – fact vs. fiction
• 21:25 Traditional Chinese Medicine and Charles Osborne
• 23:09 Take-aways for functional medicine practitioners

Additional Resources:

Genova Connect

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Akkermansia muciniphila has been getting tons of great press recently. It’s a bacterium in the gut microbiome that thrives by supporting mucin production. However, its potential to enhance metabolic health and support weight management has paved the way for innovative probiotic solutions – which is exactly what a company called Pendulum has done! Pendulum’s products are backed by cutting-edge research showing clinical efficacy.

Today we speak with Christina O’Connor, registered dietician and Senior Healthcare Account Manager at Pendulum Therapeutics. Christina breaks down all the latest research on Akkermansia muciniphila and how optimizing levels can lead to greater health outcomes.

Today on The Lab Report:

• 5:30 Christina O’Connor on her love of microbiome science  
• 8:40 Main drivers of gut health
• 10:15 Why should we care about Akkermansia?
• 13:05 Can you have too much?
• 15:20 GLP-1 effects of Akkermansia
• 17:25 Stool testing on probiotics and supporting colonization
• 22:40 What’s next for Pendulum?
• 24:15 The Fireball

Additional Resources:

Pendulum Discount Codes:

Healthcare professionals: Create a provider account HERE for wholesale pricing and get $50 off with code WSGENOVA50.

Not a healthcare professional or just want to try it out? Get 20% off your first membership order at pendulumlife.com with code GENOVA at checkout.

Genova Connect Discount Code:

Are you a consumer interested in checking your levels of Akkermansia? Use the promo code PENDULUM20 for 20% off Genova Diagnostics’ Akkermansia Assessment

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Advanced technologies and personalized approaches have been the hallmark of what we do here at Genova Diagnostics. We are frequently asked how this testing can be applied in pediatrics. Our testing is widely used to help empower parents to get to the root cause of some common childhood concerns. But there are some caveats to consider when interpreting results.

Every child is unique – so why shouldn’t their healthcare be? In this episode, we dive into the world of personalized medicine for children and how Genova’s cutting-edge testing can unlock better health outcomes for kids.

Today on The Lab Report:

• 3:25 Approaching common pediatric ailments
• 6:00 Root causes of skin issues, rashes, eczema
• 9:15 Food Sensitivity Testing and caveats
• 11:00 Stool testing in pediatrics – interp is different!
• 15:15 Pediatric nutrition testing – benefits and things to know
• 17:40 Childhood obesity and testing for metabolic syndrome
• 20:00 “What is it?” Game

Additional Resources:

GI Effects

Metabolomix+

Food Sensitivity+

Cardio Check

Genova Connect

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

We all know sugar isn’t great for our health. But is all sugar created equal? In this eye-opening podcast, we speak with the team from RxSugar. Their company creates and promotes a healthy sugar called allulose. Yes, a healthy sugar!

Dr. Rick Johnson is a leading researcher on the hidden dangers of sugar. He discusses the impact of how sugar and fructose can hijack your cravings, fuel inflammation, and contribute to chronic disease. We also meet former Google Exec Neil Gyte. His personal journey toward metabolic health found him crossing paths with the science team at RxSugar. Neil joined their company and now continues his mission to make 1 billion people world-wide metabolically healthy while promoting the benefits of allulose. Listen in and enjoy this fascinating conversation!

Today on The Lab Report:

• 5:10 Meet Dr. Richard Johnson and Neil Gyte
• 7:00 Fructose, appetite, and leptin resistance
• 14:25 Sugar industry and sub-optimal clinical trials
• 22:15 Fructose, carbs and the polyol pathway, uric acid levels
• 29:40 Neil’s a-ha moments toward metabolic health
• 34:00 Joining RxSugar -Allulose as a game-changer
• 41:40 Other artificial sweeteners
• 46:40 Allulose and the ketogenic diet
• 49:30 1BMH and diet/lifestyle factors
• 54:25 1BMH vision and the Loch Lomond swim
• 59:35 Where you can learn more!
• 1:02.10 The Fireball  

Additional Resources:

RxSugar.com  **PROMO CODE 1BMH for 20% Discount!*** (expires in June)

YouTube Videos

• Dr. Nicholas Norwitz: Allulose: Healthiest Sugar in the World & GLP-1 
• Thomas DeLauer: The Only Sweetener that Literally Shrinks Belly Fat

Published Papers:

• Alluose RCT, glucose and insulin - Journal of Functional Foods
• Allulose and Weight Loss - Nutrients
• Allulose and GLP-1 release - Nature
• The Metabolic and Endocrine Effects of a 12-week Allulose-Rich Diet - Nutrients
• Brain activity and sugar - Nutr Neuroscience
• Sweet Taste Receptor Activation  (and related article)
• Allulose & Intestines
• Allulose, Fructose, Glucose and the Small Intestine - Nutrients
• Alluose & Tight Junction Regulation - Journal of Functional Foods
• ​​Microbiome
• Allulose and the gut Microbiota 
• Allulose and High Fat Diets - Microbiome - Nutrients  
• Fructose & Metabolic Syndrome
• Fructose & Metabolic Syndrome - Cell Metabolism
• Fructose, Intracellular Pathway - J Biol

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Garlic isn't just a kitchen staple—it’s a natural powerhouse of health benefits! Packed with antioxidants and sulfur compounds like allicin, garlic supports heart health by lowering blood pressure and cholesterol, strengthens the immune system, fights inflammation, and so much more. With its antibacterial and antiviral properties, garlic has been used for centuries as a natural remedy for colds, infections, and overall wellness.

Whether eaten raw, cooked, or taken as a supplement, garlic is a simple yet powerful way to boost your health naturally. Join us as we discuss this unsung herbal hero.

Today on The Lab Report:

• 3:00 Garlic is a vegetable and a medicine
• 7:30 Herbal constituents vs. whole plants
• 9:00 Allicin
• 11:50 Cardiovascular health and immunity
• 14:20 Antimicrobial and antiviral properties
• 15:20 Garlic is useful in so many clinical conditions
• 17:20 Which form is best?
• 19:25 Get Outta Here!!!!!!!!

Additional Resources:

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Longevity isn’t about adding years to your life- it’s about adding life to your years!  We know there are many variables to health such as diet, movement, sleep, social connection, fresh air and sunlight. Each are important but some aren’t easily measured.

The Roseto Effect reveals the surprising power of tight-knit communities, social bonds, and old-world traditions in shaping our health. Join us as we tell the story of a small town in Pennsylvania called Roseto. Can community be the ultimate medicine? 

Today on The Lab Report:

• 3:20 The story of Roseto
• 10:35 Parallels to the Blue Zones
• 13:20 Can you measure the effects of community?
• 14:40 Longevity – quantity vs. quality
• 16:50 Back to the basics for health
• 19:00 How to develop social connection            

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Ever wonder what happens when your voice suddenly decides to take a vacation? In this episode, we explore the mysterious condition of laryngitis. From causes to symptoms, we can help you discover the best ways to recover and protect your voice.

Whether you're dealing with laryngitis now or just curious about how it works, this episode will give you the answers you need. Tune in for all the insights into a silent struggle!

Today on The Lab Report:

• 2:50 Patti lost her voice so we’re covering laryngitis
• 4:05 The anatomy of the voice box and power of speech
• 6:00 Laryngitis, symptoms and causes
• 8:25 Let’s go Woo – Throat chakra!
• 12:20 Disclaimer on not missing more serious causes
• 13:00 Treatment options
• 15:25 Herbal remedies
• 18:55 Prevention and the importance of self-care

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

When it comes to holiday traditions, we think of decorating Christmas trees, baking cookies, the Elf on the Shelf, or lighting a menorah. But holiday traditions are far more unusual and diverse throughout the world. Some might really surprise you!

On today’s episode, we touch on some unusual international holiday customs you’ve likely never heard while sprinkling in some clinical pearls. We also continue our podcast tradition of reading The Lab Report’s special rendition of ‘Twas the Night Before Christmas.   

Today on The Lab Report:

• 5:00 Kentucky Fried Christmas
• 7:00 The Christmas Pickle
• 8:55 Pooping logs, yule goats, & frankincense
• 14:30 Christmas disease game
• 17:30 Santa Claus towns
• 20:00 ‘Twas the Night Before Christmas

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.