The Lab Report

Many of us have heard of glutathione and understand that it is a powerful antioxidant – but why? What is it? How does it work? Understanding the mechanisms of this crucial molecule can help you fully grasp its importance. Oxidative stress and the damage of free radicals underlie the aging process and many chronic conditions. There’s no greater tool to combat oxidative stress than glutathione.

In today’s episode, we break down the science of glutathione and redox reactions. You will learn how glutathione works, how to support optimal levels, and how it connects to the methylation cycle!

Today on The Lab Report:

• 3:00 Is there more to Glutathione than you think?
• 4:20 Glutathione as a tripeptide
• 5:40 Redox reactions & the role of glutathione
• 8:30 Rate-limiting steps – cysteine, NAC
• 9:55 Holding!! Maybe it’s glycine
• 12:30 Factors needed for production
• 13:05 Measuring levels – total, reduced, oxidized
• 16:40 Clinical associations
• 18:30 Supplementing to support glutathione
• 22:00 Question of the Day
  • Is glutathione related to methylation?

Additional Resources:

Genova Connect **PROMO CODE** TheLabReport20 for 20% off your purchase

NutrEval

Methylation Panel

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Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Creatine is a powerhouse supplement known for enhancing muscle strength, endurance, and recovery. By boosting ATP production, it fuels muscles during intense workouts, leading to greater gains and faster progress. Beyond its skeletal muscle benefits, creatine supports cognitive function, fertility, sight, hearing, and just about every process in the body.

Today we discuss creatine and its many health benefits. Whether you're an athlete striving for peak performance or someone simply looking to improve overall health and vitality, consider fueling your potential with creatine.

Today on The Lab Report:

• 3:50 Creatine and methylation
• 6:00 How does the body make creatine?
• 7:55 Creatine and skeletal muscle
• 10:40 Brain health, cognition, sight, and hearing
• 13:05 Creatine and Fertility  
• 14:15 How much do we make; how much do we need?
• 17:30 Confusion around kidney function and creatine supplementation
• 19:15 Side effects and hydration

Additional Resources:

Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Dr. Bill Rawls was a practicing OB/GYN physician for decades before his health began to suffer and he was faced with the limitations of modern medicine. Embarking on his own health journey, he dove headfirst into holistic and herbal therapies and found ultimate wellness. Dr. Rawls now teaches and writes extensively about the power of herbal medicine. He’s written several books including Suffered Long Enough, Unlocking Lyme, and his latest book The Cellular Wellness Solution. Dr. Rawls even started his own herbal supplement and wellness company called Vital Plan.

In today’s episode, Dr. Bill Rawls discusses his new book, The Cellular Wellness Solution, a fresh take on the critical role our cells play in unlocking wellness and supporting health. He champions the power of herbal medicine and explains why you should too.

Today on The Lab Report:

• 4:00 Meet Dr. Rawls and hear his journey to herbal medicine
• 8:45 The Cellular Wellness Solution – 5 underlying cellular stressors
• 14:05 Microbial stress, chronic disease, and cancer?
• 21:10 Germ theory vs. Terrain theory
• 25:50 Difference between pharmaceutical drugs and herbs
• 32:15 Isolated constituents vs. whole herbs, adaptogens
• 33:20 Daily-use herbs, adaptogens, antimicrobials, anti-inflammatories
• 40:40 Current-day farming, primitive foraging, and the effects on our plants
• 44:30 Vital Plan and cautionary tales regarding supplement quality
• 50:20 The Fireball  

Additional Resources:

Dr. Bill Rawls' website

The Cellular Wellness Solution

Genova Connect **PROMO CODE TheLabReport20 for 20% off**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

In the world of athletic performance, there are plenty of health experts. But none like Ian Craig. Ian Craig takes a holistic and very personalized approach. With his joint academic backgrounds in exercise physiology and nutritional therapy, and a long successful career as a British middle-distance runner and coach, he’s been developing the concept of integrative sports nutrition for the past 20 years.

Today we speak with Ian Craig who lays out the case for personalized and holistic care when it comes to optimizing athletic performance. Through his Centre for Integrative Sports Nutrition in Scotland, he’s been a leading voice worldwide bridging the gap between conventional sports nutrition and a functional approach to health.

Today on The Lab Report:

• 5:00 Meet the amazing Ian Craig
• 6:55 Balancing life load and athletics
• 11:10 Runners vs. other athletes
• 14:30 Integrative Sports Nutrition Pyramid
• 21:00 Convincing athletes to rest!
• 24:35 Ergogenic aids
• 28:05 The line between ergogenic aids and PEDs
• 30:25 Trade-offs with ergogenic aids
• 32:45 Upcoming textbook and CISN training
• 37:15 The Fireball

Additional Resources:

Centre for Integrative Sports Nutrition (CISN)

Health Feeds Performance Podcast

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Artificial intelligence and machine learning is being leveraged in every facet of society to improve efficiency and drive innovation. Healthcare is no different. Language models, algorithms, machine learning, and more are being developed and used to help with education, behavior change, administrative tasks, predictive risk assessments, and at times, disease diagnosis.

In today’s episode, we discuss areas where the healthcare industry is harnessing artificial intelligence. With such powerful technology at our fingertips, it is always important to take a pause to debate the exciting capabilities but also its limitations and biases.

Today on The Lab Report:

• 5:25 Artificial intelligence is everywhere
• 8:36 Patient education, oversight, and bias
• 9:50 Benefit in preventing human error
• 10:40 Diagnostic models and risk assessments
• 12:20 Bias and mistakes on both sides – where’s the liability?
• 16:10 Patient confidentiality concerns
• 17:30 Wearable devices and behavioral change
• 21:00 Personalization, empathy, and the human element
• 23:00 Generative AI, novel insights, and sound data
• 24:55 Considering all traditions of medicine  

Additional Resources:

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Is it possible to be drunk without drinking alcohol? Actually, yes. There is a condition called auto-brewery syndrome whereby an imbalance in your gut microbiome can ferment carbohydrates to create alcohol. Blood alcohol levels can get surprisingly high. Though this condition is thought to be rare, it might just be underdiagnosed. Patients are dealing with legal ramifications, social stigmas, and disbelief by friends, family, and physicians.

Today we introduce the topic of auto-brewery syndrome to raise awareness that your gut microbiome can produce alcohol. We discuss how it occurs, how to diagnose it, and some strategies to treat it.

Today on The Lab Report:  

• 3:10 What is auto-brewery syndrome?
• 5:30 Causes and clinical associations
• 9:45 SIBO/SIFO – should we be checking alcohol levels?
• 10:50 Chronic tolerance and long-term alcohol effects 
• 12:20 How to diagnose ABS
• 14:30 Treatment strategies
• 17:00 Is it as rare as we think? Is there a spectrum?
• 18:12 Question of the Day
  • What patterns might we see on GI Effects and NutrEval?

Additional Resources:

Genova Connect **PROMO CODE TheLabReport20 for 20% off your purchase**

Auto-Brewery Syndrome Advocacy and Research

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Food labels can be very confusing. In fact, many of us completely ignore them. If you look at the ingredients in many processed foods, you’ve probably tried to pronounce some of the chemical compounds listed in the ingredients. The food industry adds chemicals to food to either enhance flavor and color, or to preserve shelf life. There are thousands of accepted food additives and some may have important health implications.

In today’s episode, we discuss just a few additives you might want to keep an eye out for next time you go to the grocery store.

Today on The Lab Report:

• 3:20 MSG – monosodium glutamate
• 6:40 Nitrites and nitrates
• 9:55 The “Name that Food” game
• 12:45 Sulfites are everywhere
• 13:55 Maraschino cherries are polarizing?
• 15:20 Sulfites as a top food allergen
• 16:55 Food colorings, FD&C, lakes, and blue rats
• 21:25 Artificial vs. natural flavoring

Additional Resources:

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Shakira Niazi is the founder of Basil Seed Works – an organic basil seed product line featuring the superfood ZenBasil. As a refugee from war-torn Afghanistan who was later raised and educated in the US, Shakira’s path to becoming an entrepreneur is remarkable. Although she’s known for her work with Vita Water – helping to solve the world water crisis and providing water points to poor villages around the world, her current focus is to bring basil seeds from the Far East to the Western world. Basil seeds are a natural source of fiber, omega-3 fatty acids, vitamins, minerals, and antioxidants.

In today’s show, Shakira Niazi tells us her inspiring story - from childhood refugee to being featured in Times Square. We also discuss the amazing health benefits of basil seeds and why they are the new superfood!

Today on The Lab Report:

• 5:30 Meet Shakira Niazi and hear her amazing story
• 10:30 Changing courses through the pandemic
• 20:40 Health benefits of basil seeds
• 26:40 Hydrating and using basil seeds
• 28:45 ZenBasil vs. other basil seeds
• 30:45 Where to find ZenBasil
• 32:00 The Fireball

Additional Resources:

ZenBasil

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Dr. Stephanie Venn-Watson dedicated her life to public health and veterinary epidemiology. In studying dolphins, she discovered the first essential fatty acid to be found in over 90 years – C15:0 (pentadecanoic acid). Dr. Stephanie’s discovery and further research on C15:0 has uncovered some amazing cellular health benefits and significant potential for disease prevention. With this knowledge, Dr. Stephanie pivoted and founded fatty15 - a company that produces the world’s first, and only science-backed, patented C15:0 supplement.

In today’s episode, we speak with Dr. Stephanie Venn-Watson about her latest research into the newly discovered essential fatty acid C15:0 and how supplementation with fatty15 could be a game-changer for cellular health.

Today on The Lab Report:

• 4:45 Stephanie Venn-Watson on veterinary epidemiology and dolphins
• 10:15 Pentadecanoic acid (C15:0), dolphins, and disease
• 12:20 Food sources for C15:0
• 15:35 Essential fatty acid criteria
• 18:45 Cellular stability and pentadecanoic acid
• 21:10 Red blood cell membranes and testing
• 24:10 Iron and ferroptosis
• 28:00 Measuring cell fragility
• 31:30 Ferroptosis and inflammatory cascades
• 34:05 Fatty15 supplementation
• 39:10 The Fireball

Additional Resources:

fatty15

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.

Methylation is a very important enzymatic reaction responsible for so many crucial metabolic processes. In a previous episode, we introduced the topic of methylation and the basics of this biochemical reaction.  However, there are many subtle nuances to consider when assessing whether a patient’s methylation cycle is out of balance.

Today, we dive a bit deeper into the biochemistry of methylation and peel back the layers to show how some of the specific biomarkers and backup pathways contribute to imbalance. And, what does that mean clinically? It may help to review our prior episode or use Genova’s Methylation Pathway Handout to follow along.

Today on The Lab Report:

• 2:50 Quick review of the methylation cycle
• 4:45 The important relationship between choline and betaine
• 7:05 Logical Speculation: Why is the betaine: choline ratio associated with disease risk?
• 9:35 Dimethylglycine (DMG)
• 11:15 Sarcosine and the ‘SAM disposal chute’
• 14:20 Glycine: What does it do?
• 16:55 Transsulfuration and glutathione
• 21:00 The multi-omics of the methylation panel
• 22:25 Question of the Day:  What is the stability of measuring SAM and SAH?

Additional Resources:

Genova's Methylation Panel

Dr. Michael Chapman's Methylation Webinar

Genova Connect  **PROMO CODE TheLabReport for 20% off your purchase**

Subscribe, Rate, & Review The Lab Report

Thanks for tuning in to this week’s episode of The Lab Report, presented by Genova Diagnostics, with your hosts Michael Chapman and Patti Devers. If you enjoyed this episode, please hit the subscribe button and give us a rating or leave a review.

Don’t forget to visit our website, like us on Facebook, follow us on Twitter, Instagram, and LinkedIn. Email Patti and Michael with your most interesting and pressing questions on functional medicine: [email protected].

And, be sure to share your favorite Lab Report episodes with your friends and colleagues on social media to help others learn more about Genova and all things related to functional medicine and specialty lab testing.

To find a qualified healthcare provider to connect you with Genova testing, or to access select products directly yourself, visit Genova Connect.

Disclaimer: The content and information shared in The Lab Report is for educational purposes only and should not be taken as medical advice. The views and opinions expressed in The Lab Report represent the opinions and views of Michael Chapman and Patti Devers and their guests.

See omnystudio.com/listener for privacy information.