Controlling the HIV epidemic depends on shifting from fragmented, donor-led programmes to nationally led, integrated health systems. To accompany a new joint Series of six papers, Peter Hayward, Editor-in-chief of The Lancet HIV, and Gavin Cleaver, Senior Editor at The Lancet Global Health, are joined in conversation by Solange Baptiste, Kenneth Ngure, and Charles Holmes, who worked extensively on the Series.

Together they discuss withstanding external funding shocks, meaningful community involvement, and focusing on health equity, as part of a sustainable approach to HIV prevention in Africa.

Click here to read the full series: https://www.thelancet.com/series-do/sustainable-hiv-prevention-africa

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Why do some people living with HIV struggle with sleep? Luxena Sukuraman and Alan Winston help us understand the challenges of disordered sleep in HIV, what clinicians can do to help, and practical sleep hygiene tips for people living with HIV experiencing sleep disturbances.

Click here to read the full article: https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00221-8/fulltext

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In the ongoing search for an HIV cure, promising evidence suggests that early treatment of infants might help achieve lasting HIV remission: the IMPAACT P1115 study is designed to investigate that potential. We talk to a lead investigator about what we know so far.

Read the full article: www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00189-4/fulltext

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Despite advances in treatment, HIV-associated cryptococcal meningitis continues to carry a high risk of death in Africa. In this episode, Jayne Ellis from the London School of Hygiene and Tropical Medicine discusses new research showing why targeting cytomegalovirus could be key to improving outcomes for people living with advanced HIV.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00163-8/fulltext?dgcid=buzzsprout_icw_podcast_October_25_lanhiv

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Although some countries are making great headway in eliminating vertical transmission of HIV, more than 100 000 infants acquire HIV each year. Maggie Walters and Michelle Bulterys talk us through their research into factors that affect the probability of vertical transmission and what it says about efforts to end new infant acquisitions.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00132-8/fulltext?dgcid=buzzsprout_icw_podcast_August_25_lanhiv

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Uganda is closer than ever to achieving HIV epidemic control, thanks to remarkable progress in its national response. In this episode, experts Mansoor Farahani, Wafaa El-Sadr, and Wilford L. Kirungi discuss the strategies behind Uganda’s success, the challenges that still lie ahead, and how a current global funding crisis could impact the fight against HIV in the country.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00100-6/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanhiv

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In HIV prevention and treatment, broadly neutralising antibodies have so far failed failed to deliver on their potential; could N6LS buck the trend? Richard Wu talks about a phase 1 study with some promising results.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00041-4/fulltext?dgcid=buzzsprout_icw_podcast_July_25_lanhiv

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Metabolic dysfunction-associated steatotic liver disease (MASLD) is a major cause of chronic liver disease and has become the second leading cause of non-AIDS-related mortality in people living HIV. Join Adrian Gonzalez in conversation with Grace Lui and Vincent Wong (The Chinese University of Hong Kong) as they discuss whether a dietary and exercise programme can reduce liver fat and induce resolution of MASLD in people with HIV.

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https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00032-3?dgcid=buzzsprout_icw_podcast_May_25_lanhiv

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Could cuts to international aid by the world's richest nations really undo 30 years of progress in combatting the HIV pandemic? 

Join Peter Hayward in conversation with Debra ten Brink and Rowan Martin-Hughes of the Burnet Institute (Melbourne, Australia) as they discuss their modelling study forecasting the effects of funding cuts on HIV acquisitions and mortality.

Read the full article:

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00074-8/fulltext?dgcid=buzzsprout_icw_podcast_30-04-25_lanhiv

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Sari Reisner (University of Michigan School of Public Health, Boston, USA) on gender-affirming hormone therapy for transgender, non-binary, and gender-diverse people in the US and its effects on HIV acquisition risk and viral suppression.

Read the article:

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(25)00004-9/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhiv

And the personal view:

https://www.thelancet.com/journals/lanhiv/article/PIIS2352-3018(24)00299-6/fulltext?dgcid=buzzsprout_icw_podcast_generic_lanhiv

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