The Metabolomist podcast

By biocrates life sciences

In this interview podcast you can learn how scientists and entrepreneurs create the future of metabolomics. Learn about their struggles, stresses and successes to shape the story of metabolomics as it... more

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FAQs about The Metabolomist podcast:

How many episodes does The Metabolomist podcast have?

The podcast currently has 26 episodes available.

The Metabolomist podcast episodes:

April 09, 2024 Personalized medicine & survival prediction | Robert Nagourney
Robert Nagourney MD, is Medical and Laboratory Director of The Nagourney Cancer Institute in Long Beach, California, Associate Clinical Professor, at University of California Irvine and founder and CEO of Metabolomycs, Inc. He is board certified in internal medicine, medical oncology, and hematology.
Favorite metabolite
Glutamine
Learn more about his work:
Nagourney Cancer Institute
Metabolomycs
TEDx talk
Paper we discussed in this episode
Ovarian cancer | Platinum resistance in gynecologic malignancies: Response, disease free and overall survival are predicted by biochemical signature: A metabolomic analysis
Pancreatic cancer | Diagnostic and Prognostic Performance of Metabolic Signatures in Pancreatic Ductal Adenocarcinoma: The Clinical Application of Quantitative NextGen Mass Spectrometry
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
50min
October 03, 2023 Early career scientist episode : Vitamins & metabolic syndrome | Haley Chatelaine
Haley Chatelaine s a post-doctoral fellow at the NIH’s National Center for Advancing Translational Sciences (NCATS, USA)
Favorite metabolite
Cytosine - but also Vitamin D
Paper we discussed in this episode
Paper on the absorption of fat soluble vitamins in patients with metabolic syndrome | Vitamin A and D Absorption in Adults with Metabolic Syndrome versus Healthy Controls: A Pilot Study Utilizing Targeted and Untargeted LC–MS Lipidomics
Learn more about MANA-ECM
Let Arpana Vaniya and Nicole Prince know you appreciate their effort to promote the (net)work of early career scientists as much as we do!
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
1h 4min
September 05, 2023 Multi-omics & type 2 diabetes | Sapna Sharma
Sapna Sharma is group leader at Technical University Munich (TUM) in Germany
Favorite metabolite
lysophosphatidylcholines (LPCs)
Papers we discussed in this episode
Effect of BMI on type 2 diabetes | Metabolic Signatures Elucidate the Effect of Body Mass Index on Type 2 Diabetes
More on the KORA cohort discussed in this episode and in the first paper.
Paper on medication associations with multiple omics | Discovery of drug–omics associations in type 2 diabetes with generative deep-learning models
More on the IMI-direct project
"There is enough data, but there are not enough bioinformatics tools to make sense out of it."
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
52min
August 01, 2023 Biobanks & neurodegenerative diseases | Karel Kalecký
Karel Kalecký is postdoctoral research associate

at the Institute of Metabolic Disease, Baylor Scott & White Research Institute in Dallas, TX (USA)
Favorite metabolite
Betaine (trimethylglycine)
Papers we discussed in this episode
One-Carbon Metabolism in Alzheimer’s Disease and Parkinson’s Disease Brain Tissue
Targeted Metabolomic Analysis in Alzheimer's Disease Plasma and Brain Tissue in Non-Hispanic Whites
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
55min
July 04, 2023 Flux metabolomics & cancer | Gary Patti
Garry Patti is Professor of Chemistry and of Genetics and Medicine

at Washington University in St.Louis MO (USA)
Favorite metabolite
lactate
Paper we discussed in this episode
Isotope tracing in adult zebrafish reveals alanine cycling between melanoma and liver
"Cancer cells demonstrate a remarkable degree of metabolic plasticity."
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
46min
June 06, 2023 Epidemiology & asthma | Rachel Kelly
Rachel Kelly is associate professor

at the Brigham and Women's Hospital in Boston MA (USA)
Favorite metabolite
sphingosine-1-phosphate
Papers we discussed in this episode
Metabo-Endotypes of Asthma Reveal Differences in Lung Function: Discovery and Validation in Two TOPMed Cohorts
Phenotypically driven subgroups of ASD display distinct metabolomic profiles
Activities in consortia
EnviroGenomarkers

COMETS – The consortium of metabolomics studies
COMETS analytics
On similarity network fusion
"Metabolomics is its own beast. You can’t treat it in the same way that you would genetics"
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
49min
May 02, 2023Translating metabolomics to the clinics & quality control | Jennifer Kirwan
Jennifer Kirwan is Head of the Metabolomics Platform

at the Berlin Institute of Health at Charité (Germany)
Favorite metabolite
Melatonin, a close relative of tryptophan, Jennifer Kirwan’s favorite metabolite at MetSoc last year and the metabolite chosen by our previous guest David Wishart!
Papers we discussed in this episode
Translating metabolomics into clinical practice
Don’t forget to send your constructive criticism on this opinion piece in a comment via LinkedIn
Identification and validation of small molecule analytes in mouse plasma by liquid chromatography-tandem mass spectrometry: A case study of misidentification of a short-chain fatty acid with a ketone body
Her past and present activities in the metabolomics community include
mQACC consortium, promoting best QA/QC practices in untargeted metabolomics. Learn more in the consortium’s recommendations here.
Precision medicine and pharmacometabolomics task group of the Metabolomics Society
German society for metabolome research (DGMet)
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
Finally available - Alices first book
The STORY principle - A guide to the biological interpretation of metabolomics
Also featuring some of the Metabolomists from Season 1
Available on Amazon and the biocrates webshop
...more
53min
April 18, 2023 Databases & the place of metabolomics in the clinics | David Wishart
Dr. David Wishart
Professor, Faculty of Science - Biological Sciences, University of Alberta, Canada
Wishart group @UAlberta
Favorite metabolite
tryptophan
Papers we discussed in this episode
Emerging applications of metabolomics in drug discovery and precision medicine
Towards a Rosetta stone for metabolomics: recommendations to overcome inconsistent metabolite nomenclature
David Wishart’s talk at the event on Pan-cohort studies in October 2022
“Why targeted metabolomics is essential for population health”
Sign up for The Metabolomist mailing list to be the first to hear about the latest episodes and news around metabolomics at https://themetabolomist.com
...more
43min
October 04, 2022 Lipid quantification & data visualization | Robert Ahrends
Dr. Robert Ahrends
PI Lipidomics at the Institut für Analytical Chemistry, University Vienna, Austria
Ahrends group @UniVie
Favorite lipid
lyso-sphingomyelin
Discussed paper by Peng et. al.
Identification of key lipids critical for platelet activation by comprehensive analysis of the platelet lipidome
Lipidomics pioneers mentioned in the interview
Shorthand nomenclature developed by Gerhard Liebisch
With the corresponding text from the interview
There was great work done on lipids in the 1980’s and 1990’s already. People like Britta Brüger, Andrej Shevchenko and Wolf Dieter Lehmann were pioneers of lipidomics and translated nanospray methods for the analysis of lipids. In the early 2000’s, Britta Brüger published an application of nanospray for direct infusion instrument, which made it more interesting for membrane biologists such as Kai Simons or Felix Wieland who also works in Heidelberg. They then adapted this for their own research on lipid transporters. And since then, it became clearer and clearer that mass spectrometry is the tool to go with for lipid analysis: you can analyze a lot of things simultaneously and do it in a quantitative context.
International lipidomics society – ILS
More about The Metabolomist podcast
...more
45min
September 06, 2022 Nutrition & microbiome | Hannelore Daniel
Prof. emer. Hannelore Daniel
Department of Nutrition and Food Sciences
Hannelore Daniel @TUM (German)
Favorite metabolite
lanthionine
Discussed paper by Krug et. al.
The dynamic range of the human metabolome revealed by challenges
Cited paper on sugar metabolomics by Mack et. al.
Exploring the Diversity of Sugar Compounds in Healthy, Prediabetic, and Diabetic Volunteers
Other resources
Talk on Gut Microbiome: Myths and Metabolites by Prof. Hannelore Daniel

(given at the 8th Munich Metabolomics Symposium - November 2021)
More about The Metabolomist podcast
...more
58min

FAQs about The Metabolomist podcast:

How many episodes does The Metabolomist podcast have?

The podcast currently has 26 episodes available.