Stroke and TBI Recovery with Dr. Robert Teasell MD: Part II

Noggins And Neurons Facebook Group: CLICK HERE or scan below!

1. TEASELL: ...second of all, try and develop ways in which we can move things forward. You know? Not necessarily get to the you know, I say research is always about trying to get to the truth, and we’re far from it and our piece, hopefully, will get us a little closer to it, but it clearly isn’t going to be it. But I do think, you know, I think we all agree that we’re kind of at a point where we’re stuck, you know, and stroke rehab, there doesn’t seem to be a lot of movement forward clinically, you know, we’ve gotten really good at standardized care and even that’s starting to be eroded, you know what I mean, in some jurisdictions? And I think it’s time for us to really think about what do we pivot to next? Right? What do we add onto that to make it better, get people excited about stroke rehab again and sort of end that erosion of funding that is occurring in some centers and encourage more funding in other centers?

EPISODE SUMMARY: This episode of NOGGINS & NEURONS: Stroke and TBI Recovery Simplified is Part II of our conversation with Dr. Robert Teasell and Marcus Saikaley of the Evidence-Based Review of Stroke Rehabilitation (EBRSR). In this episode we learn about:

• Brain primers – what they are and the best ways to use them

1. The vast number of randomized controlled trials on brain priming interventions that work: mirror therapy (75), bilateral arm training (66), virtual reality (99), EMG biofeedback (66)

1. Spinal Cord Injury Evidence (SCIRE) – there are two components:

• The spinal cord professional aspect for rehab professionals (similar to the EBRSR)

1. Evidence-Based Review of Acquired Brain Injury (ERABI) – focus on cognition, mental health and community re-integration challenges following brain injury

• Less evidence available compared to stroke

• Interventions that work for stroke recovery are not always translatable to Traumatic Brain Injury – the injuries are not the same stroke lesions tend to be more focal compared with TBI

1. direct evidence and can

1. Modified Constraint Induced Movement Therapy. Developed by yours truly, Pete Levine, and his colleague Dr. Steven Page

We hope you feel as inspired as we do after listening to this episode on interventions that work and other resources.

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Evidence-Based Review of Stroke Rehabilitation - 

Evidence-Based Review of Moderate-to-Severe Acquired Brain Injury - 

Spinal Cord Injury Research Evidence - 

Collaboration of Rehabilitation Research Evidence

Collaboration of Rehabilitation Research Evidence twitter

Dr. Teasell’s Google Scholar Page 

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app:

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

• Sept. 28, 11:10 AM.Recovery from Brain Injury: The Nexus of Neuroscience and Neurorehab. American College of Rehabilitation Medicine. *Virtual 

• October 28, 8:00 PM (ET) The Neuroplastic Model of Spasticity Reduction *Virtual. 

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

MUSIC:

“Soft Inspiration” by Scott Holmes/Scott Holmes Music/scottholmesmusic.com

Stroke and TBI Recovery with Dr. Robert Teasell MD: Part I

Noggins And Neurons Facebook Group: CLICK HERE or scan below!

PETE:  When I first got involved in clinical research, I remember there was this statistic that the lag time between bench and bedside and rehabilitation was 15-20 years and the idea was you know that in oncology you couldn’t have that much lag time because people die of cancer whereas typically nobody dies of bad therapy. Do you think that the translation is still that long? What would you estimate is the, or is it impossible to estimate, it depends on the therapist kind of deal?

TEASELL: It depends on the treatment and it depends on the kind of support that the treatments got. A lot of it’s cultural as well but I would say that 15-20 years...you know from moving into the research into regular clinical practice would be considered to be a very early adoption. That would be considered to be rapid. It’s more than 15-20 years. In some cases, I think it’s a couple generations. You know, when we sit down with our therapists and ask them, you know, ‘do you use the adjunct therapies?’ the answer is usually not a lot and why? Well there’s a number of reasons-timing, but it’s just like it’s not part of the culture. Like it’s just not part of the culture. You know...And you ask them, ‘would you like to do it?’ ‘Of course, we would, I mean, why wouldn’t we? Right. I wouldn’t mind trying something new or trying this new technology or this new treatment but I don’t know where to start; it’s not what we’ve traditionally done; it’s not what we tend to do; I’m busy enough as it is’ and so these treatments don’t get incorporated or added. So, you know, the reasons are legit, they’re fine, but I mean, if we’re looking at ways that we might be able to further improve recovery and the next big step...cuz you know, one of the things that you get a feeling in stroke rehab is people just not sure where we’re gonna go next. It strikes me that this is a lost opportunity that we could take advantage of.

EPISODE SUMMARY: This episode of NOGGINS & NEURONS: Stroke and TBI Recovery Simplified is Part 1 of a captivating interview with Dr. Robert Teasell and Marcus Saikaley of the Evidence-Based Review of Stroke Rehabilitation (EBRSR). Join us as we learn about:

• The history of EBRSR, including Teasell’s original work:

• To demonstrate that chronic pain can be debilitating, the evidence supporting facts around chronic pain, patient advocacy and policy change.

• The right amount of intensity

We hope you find value in part 1 of our conversation to the extent you feel empowered to look at your current practice and discover possibilities to improve client and clinic outcomes.

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Evidence-Based Review of Stroke Rehabilitation - 

Evidence-Based Review of Moderate-to-Severe Acquired Brain Injury - 

Spinal Cord Injury Research Evidence - 

Collaboration of Rehabilitation Research Evidence

Collaboration of Rehabilitation Research Evidence twitter

Dr. Teasell’s Google Scholar Page 

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

• Sept. 28, 11:10 AM.Recovery from Brain Injury: The Nexus of Neuroscience and Neurorehab. American College of Rehabilitation Medicine. *Virtual 

• October 28, 8:00 PM (ET) The Neuroplastic Model of Spasticity Reduction *Virtual. 

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

More Listener Q's & More StrokEngine

Noggins And Neurons Facebook Group:

PETE: And having other kinds of problems like diabetes flares up or whatever it is...and so they cycle back through to the therapist and what the therapist sees is not the people getting better because they’re gone. They’re Kathy Spencer...they’re people that are living their life and going to work and doing stuff that’s important to them. The therapists keep seeing the sick people, who are often sick because they don’t exercise, and the therapists don’t interface with the successful survivors. And that’s the other thing, like, some of the people that I’ve met through some of the survivor Facebook groups, they’ve come to my talks. And you know, I’ve got to meet them, and they’re still working and they’re pressing and they’re exercising and those people I think it would be good if you knew who those people were. And that you kept in touch with them. We trashed Facebook in the last episode so now let’s say something nice. There’s some groups on Facebook that you can get engaged in that are really good to help you know the full rainbow of the kinds of survivors that exist.

DEB: Yeah...

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb got into more N & N FB group member questions and another Stroke Engine intervention. We discussed:

• Goal setting strategies to instill motivation for recovery:

• Benefits of involving athletic trainers for stroke recovery success

• Understanding the fatigue factor and the just right challenge

• Aerobic exercise following stroke to improve cardiovascular health, quality of life, leg and body function, spasticity, cognition, dexterity and more!

 As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

• The Power of Habit by Charles Duhigg

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app:

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

• Sept. 28, 11:10 AM. Recovery from Brain Injury: The Nexus of Neuroscience and Neurorehab. American College of Rehabilitation Medicine. *Virtual 

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

EPISODE TITLE: Deb's Trip & Listener Questions

Noggins And Neurons Facebook Group:

DEB: I think too, that if we do a case study and we talk about it and we kinda say what our process is and the way that we think about things and link it to the research, maybe it will help clinicians to know that they’re probably thinking about things the right way. I think sometimes there’s just insecurities around trying something new. Or, even doing what you think you should do. Especially if you don’t have a mentor available to you...which I always recommend anybody have a mentor of some type or even work in a clinic where there are seasoned therapists there or at least people who have some more experience than you do because it’s hard. Especially when you’re a new grad. It’s hard to put all those pieces together in a meaningful way. And then...yeah!

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb talked about Florida travels and listener questions. We talked about:

• Deb’s Florida travels-rural towns and ALF visiting leniency, catching up with cousins, dolphins and beauty.

We hope you enjoy this fun conversation as much as we did!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Improvement of functional was greater in hemorrhagic than ischemic stroke

Cognitive Rehabilitation Training Course (ACRM)

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

• Sept. 28, 11:10 AM. Recovery from Brain Injury: The Nexus of Neuroscience and Neurorehab. American College of Rehabilitation Medicine. *Virtual 

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

Brain 'Splain Pete Style

Noggins And Neurons Facebook Group

EPISODE TITLE: Brain ‘Splain Pete Style

DEB: What?

PETE: So, I’ve got a funny story for you...So, my college had a career development day. And they wanted people to do an hour, hour and a half on whatever they wanted to do and people were doing it on how to run a good zoom meeting and how to grab a great power point and a lot of other interesting things and of course I pitched my crazy, ‘how does the brain really learn? and ‘how can we engage students if we look at it from a neuroscience perspective?’ And they said ok, we’ll give you an hour and a half to do that, so I show up at the college today and I go to the room that I’m supposed....it’s in this big convention center....and I go to the room I supposed to be in and, ah, the door’s locked. So I called the lady that runs the whole thing and she says, “well, um” I said ‘when will the door be unlocked?’ And she said, “well, um, at 9:00 they’ll be coming in,” this is by the way at 1:00 in the afternoon or 12:00 in the afternoon. “At 9:00 they’ll be coming in and they’ll set up everything so you have it ready” And I’m getting this weird vibe from her and I realize I’m there a day early.

DEB: Awesome!

PETE: And then I said to her, ‘I got a funny story, I’m out in front of the door waiting for somebody to unlock it like an idiot. So, ah, that was fun. But here’s the favor I have to ask you...So what I would like to do is, I know we had an agenda tonight but I would like to do my entire talk for tomorrow for an audience of one and that way I get to practice it.

DEB: That’s a great idea!

PETE: You like that idea?

DEB: I do...

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete presents valuable information on “The Brain and How it Learns Simplified: Driving Cortical Plasticity.” We talked about:

• Deb’s upcoming road trip and her fast car.

Pete practices his presentation and Deb enjoyed being the audience. We hope you find the information valuable too.

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Spark: The Revolutionary New Science of Exercise and the Brain by John Ratey, MD with Eric Hagerman

'I only have half a brain'

The homunculus in 3D

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

StrokEngine: A-Z Treatment Options 

Noggins And Neurons Facebook Group

DEB: Acupuncture has to do with stimulating certain trigger points along the body’s meridian lines to help regulate the flow of energy or chi. They looked at this in the different phases of stroke and they found that it’s not more helpful in general. So they looked at in terms of balance, cognitive function, depression, dexterity, independence a lot of other things, that it’s not really effective for. But you know what it’s effective for? Swallowing problems. It’s effective for dysphagia.

PETE: What? Get out!

DEB: I’m not kidding you....

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb talk start a conversation on stroke treatments listed on the Stroke Engine website. We started the episode with a listener question about the number of repetitions needed for the brain to change and motor recovery to occur. Pete shared more research and we talked about what it means for real life recovery. We also discussed:

• Growth mindset, learning and recovery

Pete and Deb took a deep dive into these topics, looking at pros and cons of each along with next steps for clients and clinicians, including measuring change.

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

How many repetitions does it take to drive brain changes and movement changes in folks with brain injury/ stroke?

• Carey et al., subjects with impaired grasp-and-release 1,200 total reps of a finger-tracking exercise and demonstrated significant cortical reorganization and functional improvement compared with control subjects.

This study showed that there were similar outcomes under three dosages of repetitive practice...

There were four groups:

• Group A (the control) received 3 hours of traditional therapy consisting of passive movement, therapeutic positioning, and weight bearing on the affected limb. Throughout study the score increased ~3 points for the Fugl-Meyer.

The Brain Boosting Power of the Mighty N -Back

The N-Back Game

How the N-Back Game improves fluid intelligence with training on working memory

Video: Virtual Reality Gait Training | Brooks Rehabilitation

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal App

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

What Makes a Great Therapist?

Noggins And Neurons Facebook Group

“I want to do what I did with the smaller group earlier this week and read you my favorite letter. Because, I think the thing that pushes me and everything...My why...My purpose...are embedded in the idea of service in care to others. Meaning all of those to self, to family, to community, the society. And, if you’re not clearly in touch with just how unbelievable it feels to care for others, my favorite letter of several hundred thousand will hint.”

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb talk about qualities that make someone a good clinician. Here’s what we came up with:

• Understanding qualities of excellence can aid in selecting the right therapist

Pete and Deb talk about these topics and more. We share stories and thoughts from personal experiences and hope this helps you in your clinical practice or recovery.

• Empathic Responses to Affective Film Clips Following Brain Injury and the Association with Emotion Recognition Accuracy

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

Sleep: Vital for Everyone, Essential for Survivors

Noggins And Neurons Facebook Group

DEB: Did you know that rest and sleep are considered occupations? The Occupational Therapy Practice Framework is a document that we use in occupational therapy to guide the process of what we do in OT and it also explains what occupations are and what they mean. And sleep preparation is a thing in the OTPF and it talks about routines. Bedtime routines to prepare yourself, to prepare the body, to prepare the mind that it’s time to wind it down and get ready to fall asleep. They talk about how routines that prepare the self for comfortable rest are important and then they have some examples; grooming, get your clothes out for the next day, reading and listening to music, saying goodnight to others and engaging in meditation or prayers before bed, determining the time of day and length of time that somebody desires to sleep. And then how much time somebody needs to be awake...so being mindful of that and planning for that. And establishing healthy sleep patterns. When you start with these habits you can build them into a routine and then your body just kind of gets used to looking for that.

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb talk about all things sleep. In this conversation we cover:

• Sleep disorder statistics in stroke survivors

Pete and Deb also talk about avoiding caffeine and sugar before bed time to improve sleep quality; the value of routine for sleep preparation and establishing healthy sleep patterns and natural ways to set the internal clock for improved sleep quality.

We hope you enjoy our thoughts and find them mentally stimulating and thought provoking!

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Neurobiology of Sleep and Circadian Rhythms

Sleep and Stroke

Male seahorse "birthing" baby seahorses!

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

Dr. Jones, TexMex, and Synaptic Connections

Noggins And Neurons Facebook Group

PETE: Hey everybody, this is Pete. I just wanted to jump in real quick and tell you about a mistake I made. I forgot to put the bio for our interview with Dr. Theresa Jones ahead of the actual interview. So, I’m gonna put the bio at the beginning of this episode, which kinda works because it is a review of the episode and what we learned, when we did interview Dr. Jones. Thanks!

DEB: New clinicians working in the world of stroke recovery need to understand what is too much too soon. And I think she made some good points about it. That early mobility doesn’t mean early intensity. So, you know, early mobility really is to get the person up so that other systems in the body don’t start to fail them. And...which would impact negatively, negatively impact their recovery. So we keep them healthy while they’re still in that acute stage so that when they enter that more subacute phase they can participate.

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb have a stimulating conversation about our interview with the Great, Dr. Theresa A. Jones, a behavioral neuroscientist from University of Texas at Austin. Some things we reflect on include:

• How repetition rules in learning. In fact, intensity and learned non-use came up again. It’s nice to hear Dr. Jones’ perspective and how to think and talk about these topics in practice and recovery.

We hope you enjoy our thoughts and find them mentally stimulating and thought provoking!

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:1

Repost of articles posted on the Dr. Jones interview:

Theresa A. Jones, PhD Articles:

Jones TA (2017) Motor compensation and its effects on neural reorganization after stroke. Nature Reviews Neuroscience. 18:267-280.

Clark TA, Sullender C, Jacob D, Zuo Y, Dunn AK & Jones TA (2019) Rehabilitative training interacts with ischemia instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex.  Journal of Neuroscience, 39: 8471-848

Dutcher AM, Truong KV, Miller DD, Allred RP, Nudi E & Jones TA (2021) Training in a cooperative bimanual skilled reaching task, the popcorn retrieval task, improves unimanual function after motor cortical infarcts in rats. Behavioural Brain Research, 396:

Dorothy A. Kozlowski, PhD and Theresa A. Jones, PhD Articles:

Use-Dependent Structural Events in Recovery of Function

Use Dependent Exaggeration of Neuronal Injury After Unilateral Sensorimotor Cortex Lesions

Use Dependent Exacerbation of Brain Damage Occurs During an Early Post-Lesion Vulnerable Period

Neural Plasticity and Neural Rehabilitation Following Traumatic Brain Injury

Combinatorial Motor Training Results in Functional Reorganization of Remaining Motor Cortex After Controlled Cortical Impact in Rats

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Learned Non-Use Article:

Barth, J., Geed, S., Mitchell, A., Lum, P. S., Edwards, D. F., & Dromerick, A. W. (2020). Characterizing upper extremity motor behavior in the first week after stroke. PloS one, 15(8), e0221668. 

VECTORS trial

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com

Rodents and Recovery with Behavioral Neuroscientist Dr. Theresa A. Jones

Noggins And Neurons Facebook Group

Rodents and Recovery with Behavioral Neuroscientist Dr. Theresa A. Jones

PETE: So one of the things I find interesting about fMRI’s...it doesn’t directly measure neuroplastic change and I always thought you would have to get really lucky drilling a hole through the skull, through the meninges and somehow get a very big microscope and see actual synaptogenesis and you’d have to get very lucky that those neurons just happen to get connected at that point. But you’re saying in this model they glow green and you can see that process happening in individual neurons?

DR. JONES: I feel so lucky to have lived long enough for these techniques in neuroscience that I had nothing to do with to be dropped into my lap. Yeah these, they’re transgenic mice that seem to be normal except they have been manipulated to have fluorescent proteins expressed in a subset of their cortical neurons, so that you can see the dendritic barbers of the cortical neurons either through thin skull or through implanted windows. And so you can watch the same parts of a neuron over time and see how they change and because you have the windows are big, you look at a whole big dendritic field and at least with cortical changes in response to learning new ways of moving, those changes seem not just to be in one neuron. I mean there’s crazy activity that gets instigated and, after a stroke, there’s crazy activity...by activity I don’t mean activity...I mean structural changes in neurons. A structural neural plasticity um is just explosive in response to strokes because that’s the remodeling process.

EPISODE SUMMARY: In this episode of NOGGINS & NEURONS: Brain Injury Recovery Simplified, Pete and Deb engage in stimulating conversation with Dr. Theresa A. Jones, a behavioral neuroscientist from University of Texas at Austin. We talk about:

• Translating research from bench side to bedside and what that means in terms of informing clinical practice and brain injury recovery

• writing, which is a skill

We hope you enjoy our conversation with Dr. Jones. She is a true delight and makes information about brain research and stroke recovery understandable.

As always, we want to hear your top takeaways!

LINKS TO ARTICLES, BOOKS AND OTHER IMPORTANT INFORMATION:

Theresa A. Jones, PhD Articles:

Jones TA (2017) Motor compensation and its effects on neural reorganization after stroke. Nature Reviews Neuroscience. 18:267-280.

Clark TA, Sullender C, Jacob D, Zuo Y, Dunn AK & Jones TA (2019) Rehabilitative training interacts with ischemia instigated spine dynamics to promote a lasting population of new synapses in peri-infarct motor cortex.  Journal of Neuroscience, 39: 8471-848

Dutcher AM, Truong KV, Miller DD, Allred RP, Nudi E & Jones TA (2021) Training in a cooperative bimanual skilled reaching task, the popcorn retrieval task, improves unimanual function after motor cortical infarcts in rats. Behavioural Brain Research, 396:

Dorothy A. Kozlowski, PhD and Theresa A. Jones, PhD Articles:

Use-Dependent Structural Events in Recovery of Function

Use Dependent Exaggeration of Neuronal Injury After Unilateral Sensorimotor Cortex Lesions

Use Dependent Exacerbation of Brain Damage Occurs During an Early Post-Lesion Vulnerable Period

Neural Plasticity and Neural Rehabilitation Following Traumatic Brain Injury

Combinatorial Motor Training Results in Functional Reorganization of Remaining Motor Cortex After Controlled Cortical Impact in Rats

Combining Multiple Types of Motor Rehabilitation Enhances Skilled Forelimb Use Following Experimental Traumatic Brain Injury in Rats

Learned Non-Use Article

Barth, J., Geed, S., Mitchell, A., Lum, P. S., Edwards, D. F., & Dromerick, A. W. (2020). Characterizing upper extremity motor behavior in the first week after stroke. PloS one, 15(8), e0221668. 

VECTORS trial

• Dr. Jones's talk: Tribulations in Translation from the Preclinical Side of Stroke Neurorehabilitation 

Questions and Comments about the podcast?

• [email protected]

Donate to The Noggins And Neurons Podcast with your PayPal app. 

Pete’s blog, book, Stronger After Stroke, and talks.

• Blog

Deb's OT Resources:

• Deb's OT resources

REQUEST TO BE A GUEST ON NOGGINS & NEURONS. If you’re passionate about stroke recovery and have information or a story you believe will help others, we’d love help you share it on the show. Complete the guest request form below and let’s see if we’re a good fit!   Guest Request Form

Music by scottholmesmusic.com