In episode 38, I cover the scientific evidence on the vitamin B3, niacin. Niacin's discovery has a rich history as it took scientists decades to prove that the epidemic of Pellagra was caused by niacin deficiency. Today, niacin is being investigated for its effects on longevity and successful aging. Niacin is converted into the essential signaling molecule NAD+. High dose niacin supplementation has been investigated for reducing cholesterol and heart disease risk; however results are controversial. Abnormal responses to niacin are implicated in Schizophrenia. I also discuss the impact of niacin on skin health and the best food sources. Tune in for the details!

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In today's episode we dive into the function of estrogen and progesterone which go far beyond just female reproduction. A great amount of evidence is coming out on the neuroprotective effects of estrogen following an acute brain injury such as concussion or a stroke. Evidence also suggests that estrogen can induce fear memory extinction and reduces fear memory recall which can have important implications for post traumatic stress disorder. We dive into the effects of these hormones on the brain, mood, physiology, how to obtain healthy levels and more.

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This week on The People's Scientist podcast, I share with you an update on the first approved clinical trial using CRISPR gene editing in North America for cancer therapy. This clinical trial aims to recruit 18 patients living with cancer to test the safety and efficacy of CRISPR gene editing the patients' T-cells to seek out and kills their own cancer cells.

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In episode 3 of our Vitamin Miniseries we discuss the scientific evidence on Riboflavin. I share with you signs and symptoms of a riboflavin deficiency, who is at risk for a riboflavin deficiency, the function of riboflavin in our body, and the highest food sources of riboflavin.

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In today's episode of the People's Scientist podcast, we cover some scientific evidence of cold therapies such as whole body cryotherapy and cold adapted showers on measures of oxidative stress, inflammation, and mood. The clinical evidence supports that cold therapy may have benefits for athletes, those living with inflammatory conditions such as rheumatoid arthritis, multiple sclerosis, and depression. Tune in for all the details!

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In today's episode we take a neuroscience perspective on type 2 diabetes. In this episode, I share a study published earlier this week of which I am a co-author, in the journal Nature. We elucidate how even though nicotine may feel pleasurable and rewarding, it can still send a stress signal to the medial habenula and pancreas. This signal causes an increase in blood glucose levels so we have the energy to fight or flight, which is our typical stress response. If this circuit is chronically activated by nicotine, it could increase the risk for type 2 diabetes.

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In this week's episode, we dive into the clinical evidence on how adding garlic to the diet is associated with a lower risk of stomach and colorectal cancer. Garlic supplementation may induces some benefits for heart health, immunity, and inflammation. I also provide some suggestions on how to reduce garlic odor, the main deterrent to garlic intake, based on two scientific investigations.

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In the last two decades bacteria have been detected in the brains of patients who died with Alzheimer's disease and in the atherosclerotic plaques of those with coronary artery disease. In today's episode, we further dive into how bacteria can induce and accelerate two of the most devastating chronic diseases and the latest science on how we can treat heart disease and Alzheimer's in the future.

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In episode 2 of our Vitamin Miniseries, I share some evidence with you on the first vitamin ever discovered, thiamine. Thiamine is a B vitamin that plays an important role in our energy metabolism and nervous system functioning. Deficiencies in thiamine may be more common than we think. Tune in to this episode to hear what diets may increase our odds of deficiency, signs of deficiency, and what foods to eat to make sure we are getting adequate amounts.

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Many news headlines in the last few weeks are stating that people are dying from e-cigarette use and that it is far more dangerous than initially thought. Is any of this true? Well in today's episode we dive into the CDC reports and many studies published within the last year that looked at the lung and cardiovascular effects of e-cigarette use to find out the truth.

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