The People's Scientist

In episode 138 I dive into two of my recent publications. In the first clinical trial I discuss how we used the technique of metabolomics to quantify the plasma oxylipidome. Here we link smoking status to peripheral artery disease with the oxylipidome. In the second study, we provide evidence that genetics may play a role in the propensity for nicotine addiction, cigarette smoking, and lung disease. Good science is never accomplished alone but as part of a great collaborative team. I thank my contributors and collaborators for their hard work and input to both of these studies. Tune in for the scientific details!

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In Episode 137 of The People's Scientist podcast, I share some scientific evidence on the Neuroscience and Psychology of Greed. Often thought to be a personality trait with negative connotations, I offer an alternative perspective. I go through a Psychology test with you to determine our level of greed, other personality traits associated with greed, and insightful neuroimaging studies. Tune in for details!

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A recent study by Li and colleague coming from the Charles Zuker lab suggests that the wanting of sugar and fat has to do with a specific population of cells within the vagus nerve that responds to sugar or fat to activate my favorite brain region, the nucleus of the tracts solitarius (nTS). This was independent of taste in the mouth and smell from the olfactory epithelium. These findings can explain why we still enjoyed consuming sweet and fatty foods with the lost of taste from COVID and other viruses. Can we use this information to help regulate sugar and fatty food cravings? Tune in to find out more.

Main Reference: Li et al. Gut Brain Axis For Fat Preference. Nature. 2022; 610:722.

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Happy Halloween my People's Scientist Army! Today in Episode 135 I dive into some scientific evidence on the Neuroscience and Psychology of Nightmares. I discuss many theories on nightmares dating back to the 1800s and earlier. Nightmares used to be called Incubus or Wizard Pressing, thought to be related to supernatural phenomenon. I also go into observational studies that identified different personality traits associated with the prevalence of nightmares and sleep paralysis. Tune in for details!

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In Episode 134 of The People's Scientist podcast, I go into the details on the Neuroscience and Psychology of Embarrassment. We study embarrassment because it may prevent us from pursuing health promoting activities like social interactions, going to the gym, or seeking help. What brain regions are involved, what types of embarrassing scenarios exist, what personality traits are associated with higher embarrassability, and how we can use this information to help us cope with embarrassment. I get into those details and more.

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In Episode 133, I discuss my own theory on the modern motivations of humans today. With the onset of technology, I believe that our motivations have adapted and changed. At the root, we all crave to be seen. That is it. I go on to explain 3 other levels to human motivation. I expound upon how we can use this information to our advantage to benefit our everyday interactions and relationships. Tune in for details!

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In Episode 132 of The People's Scientist podcast, I talk about how Scientists speculate that the prevalence of social anxiety has increased in the last several years. I offer an alternative, that in part, these observations may be explained by us having the opportunity to be more introverted over the pandemic. So is it introversion or social anxiety? I talk about the neuroscience, diagnostic criteria, and treatment strategies for social anxiety disorder.

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In Episode 131 of The People's Scientist podcast, I dive into the Neuroscience and Psychology of Rejection. Social rejection is believed to recruit brain regions involved in feeling social pain. As a result, many of us may have missed opportunities because of the fear of this pain. But guess what? When people were surveyed about their missed opportunities and moments of rejection, missed opportunities ranked 3 times higher for regret. In today's episode I talk about why and how we experience rejection and how we can use this information to our advantage. Tune in for details!

Want to buy me a coffee to say thanks for the episode? You can do so via Venmo or Patreon below.

Venmo ID: Steph-Cal

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Jia Jiang's "What I learned from 100 days of rejection" talk : https://www.ted.com/talks/jia_jiang_what_i_learned_from_100_days_of_rejection?language=en

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In Episode 130 I dive into a recent publication by Li et al. published this year in Nature that identified an exercise metabolite, lac-phe, that reduces food intake and induces fat loss. The scientists conducted a series of experiments to illustrate that certain types of exercise increase circulating lac-phe in the blood which is likely the mechanism behind reduced appetite, food intake, and enhanced fat loss. Tune in for details!

Reference: Li, V.L., He, Y., Contrepois, K. et al. An exercise-inducible metabolite that suppresses feeding and obesity. Nature 606, 785–790 (2022). https://doi.org/10.1038/s41586-022-04828-5

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In Episode 129 of The People's Scientist podcast, I dive into a ton of scientific evidence on this highly requested topic. Attention control is our ability to regulate to what we give our attention. The opposite would be being distracted, ruminating on negative things, and having intrusive thoughts. Attention control is incredibly important for high productivity and mental well-being. In this episode I discuss over 10 evidence based strategies on how we can enhance our attention control. Tune in!

Want to buy me a coffee to say thanks for the episode? You can do so via Venmo or Patreon below.

Venmo ID: Steph-Cal

Patreon: https://www.patreon.com/join/DrSCaligiuri

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Website source for diet nutrient calculations: https://nutritiondata.self.com

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