The Jews asked for a sign, and Jesus said to them, “Destroy this temple, and in three days, I will raise it up.” Clearly, the people who heard Jesus and even his disciples, at the time, misunderstood what He really meant. It was after the Resurrection when Jesus rose from the dead that they remembered, and they had the understanding that Jesus was speaking of the temple of His Body. He is the first of the end-time sanctuary for God. So on account of the Redemptive work of Jesus, the Third Person of the Trinity, the Third Person of the Godhead, the Holy Spirit can now come and enforce the Redemption through Jesus, making us who will believe in Him the Sanctuary for God.