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The Substance Movie Reaction, Recap, Commentary, Analysis, Spoiler Review, & Ending Explained! Greg Alba, Roxy Striar, and I are diving into The Substance (2024) – the latest horror thriller stirring up excitement! Join us as we react, recap, and analyze every twist and turn of this eerie film, directed by Philip W. Johnson, and starring Demi Moore, Margaret Qualley, and Ray Nicholson. Together, we’ll be unpacking the symbolism, breaking down the intense moments, and giving our thoughts on that unforgettable ending. With Demi Moore delivering one of her most haunting performances and Margaret Qualley’s compelling transformation, The Substance blends horror with psychological thrills and deep social commentary.

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