The overall goal of the vRESPOND study is to provide a clinically feasible and cost-effective method to manage negative dysphotopsia (ND). The study aim to use MRI-based patient-specific eye-models to uncover the underlying optical origin of ND through ray-tracing simulations. They subsequently aim to develop a Virtual Refractive Surgery application for the prevention and treatment of ND.

In terms of specific research aims:

•  comprehensive clinical evaluation will be made of 60 ND patients and 60 pseudophakic controls both in terms of objective ophthalmic measurements and standardized questionnaires.
•  Based on these data, ray-tracing analyses will be performed using the patient-specific, MRI-based, eye-models to:
  1. elucidate the mechanism for ND
  2. determine the key aspects of IOL design to prevent ND
  3. develop the Virtual Refractive Surgery model to preoperatively select high-risk patients and guide to the optimal IOL-type to prevent ND for these high-risk patients

 

Further details: https://education.escrs.org/virtual-refractive-surgery-for-the-prevention-of-negative-dysphotopsia-vrespond-study/