What does famine data teach us about epigenetics? (Note: Anne and Ruby are not "pro-famine" — they just provide some fascinating and useful information!) What about twins? And how did bees get in there? We're on a total science-nerd learning path today, and it's great fun.
Our environment can turn genes off and on, so it's not "nature vs nurture," it's "nature AND nurture." How genes and our environment work together or at odds has real impact not just on our individual health but potentially on our offspring and theirs!
Why are famines, devastating as they are, useful for study? Because while the stress and nutritional deficits profoundly affect those suffering, they can also cause cascading epigenetic effects that continue or appear generations later.
Which brings us to now and what we can learn: One, what you eat now may matter 100 years from now, even if you're no longer around, so maybe sideline the sugar and processed stuff for occasional consumption? And two, issues you're experiencing now may be at least partly caused by what your great-grandmother ate and the environment she lived in.
This is such a fascinating conversation and it sheds light on struggles of mental health, weight, fertility, disease, and more. We hope you'll take a look at the resources included below for more information. And as always, we encourage you to share this episode with anyone you believe could benefit.
Find more about Ruby and Anne and The Whole Pineapple at https://thewholepineapple.com/!
Resources: Anne's References
Dutch Famine info from Nature Epigenetics: Tales of adversity | Nature
NYT article about it, showing differences in methyalation with samples taken 70 years after
The Famine Ended 70 Years Ago, but Dutch Genes Still Bear Scars - The New York Times (nytimes.com)
True scientific article
Prenatal famine exposure and adult health outcomes: an epigenetic link | Environmental Epigenetics | Oxford Academic (oup.com)
And the citation for it: Prenatal famine exposure and adult health outcomes: an epigenetic link - PubMed (nih.gov)
Irish potato famine and growth of the asylum system, was increase in schizophrenia (in the high risk age ranges right timeline post famine) to blame?
Irish Potato Famine: Date, Cause & Great Hunger - HISTORY - HISTORY
The Great Irish Famine (1845-52) and the Irish asylum system: remembering, forgetting, and remembering again - PubMed (nih.gov)
Did the Great Irish Famine increase schizophrenia? - PubMed (nih.gov)
Ruby's references:
What it takes to make a queen bee
New York Times Dutch Famine Article: NYT article
Longevity Article on The Great Hunger https://vocal.media/longevity/the-irish-potato-famine-and-epigenetics
The China Study:
https://nutritionstudies.org/the-china-study/
Goodreads page: https://www.goodreads.com/book/show/178788.The_China_Study
Amazon: https://a.co/d/aV7zA1p
Nurses Health Study
American Journal of Public Health article